Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Nancy M. Joseph"'
Autor:
Nancy M. Joseph, Kwun Wah Wen
Publikováno v:
Clinical Case Reports, Vol 11, Iss 2, Pp n/a-n/a (2023)
Abstract This is an unusual adult case of a metastatic well‐differentiated neuroendocrine tumor with incidentally discovered subtle involvement of Langerhans cell histiocytosis (LCH), a clonal proliferation of Langerhans cells. It is important to r
Externí odkaz:
https://doaj.org/article/a927b1f5032448e99130223a88977a5d
Autor:
Robin K. Kelley, Nancy M. Joseph, Halla S. Nimeiri, Jimmy Hwang, Laura M. Kulik, Zoe Ngo, Spencer C. Behr, Courtney Onodera, Karen Zhang, Andrea G. Bocobo, Al B. Benson, Alan P. Venook, John D. Gordan
Publikováno v:
Liver Cancer, Pp 1-11 (2021)
Background: The mammalian target of rapamycin (mTOR) pathway is upregulated in nearly half of hepatocellular carcinoma (HCC) tumors and is associated with poor prognosis. In preclinical models of HCC, the combination of mTOR pathway inhibition with t
Externí odkaz:
https://doaj.org/article/cbb627c3bf394483ab5c3ac74db1bf71
Autor:
Naoki Akanuma, Nancy M. Joseph, Matthew Stachler, Spencer Behr, Toshiyuki Takahashi, Ryan M. Gill
Publikováno v:
Human Pathology Reports, Vol 29, Iss , Pp 300671- (2022)
GNAQ, GNA11, and GNA14 are paralogues in the GNAQ family that are mutually exclusively mutated in a group of vascular neoplasms with thin-walled capillary-like vasoformative growth, which occur at multiple sites. The primary liver tumor in this categ
Externí odkaz:
https://doaj.org/article/e8c5a8c157014e2580217a4392916e10
Autor:
Benjamin Goode, Gourish Mondal, Michael Hyun, Diego Garrido Ruiz, Yu-Hsiu Lin, Jessica Van Ziffle, Nancy M. Joseph, Courtney Onodera, Eric Talevich, James P. Grenert, Iman H. Hewedi, Matija Snuderl, Daniel J. Brat, Bette K. Kleinschmidt-DeMasters, Fausto J. Rodriguez, David N. Louis, William H. Yong, M. Beatriz Lopes, Marc K. Rosenblum, Nicholas Butowski, Tarik Tihan, Andrew W. Bollen, Joanna J. Phillips, Arun P. Wiita, Iwei Yeh, Matthew P. Jacobson, Boris C. Bastian, Arie Perry, David A. Solomon
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Chordoid glioma is a rare low-grade brain tumor that originates from the anterior wall of the third ventricle where surgical resection is challenging; the clinical outcome of patients after subtotal resection or disease recurrence is poor. Here the a
Externí odkaz:
https://doaj.org/article/8ff58d0463294f3b9772e2541cb2ebc5
Autor:
W. Michael Korn, Sanaa Tahiri, Regina Linetskaya, Ryan Courtin, Sharvina Ziyeh, Anna Ong, Elizabeth Dito, Alan P. Venook, R. Kate Kelley, Eric A. Collisson, Margaret A. Tempero, Peter Kuhn, AmirAli Talasaz, Nancy M. Joseph, Olga M. Mirzoeva, Jessica Van Ziffle, Tanios Bekaii-Saab, Andrew H. Ko
Supplemental figure 3. Mutation frequencies in pre-and on-treatment plasma samples as determined by next-generation sequencing of cfDNA using the Guardant360 assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d178c527541c3780f64e59a214d8d0
https://doi.org/10.1158/1078-0432.22459914.v1
https://doi.org/10.1158/1078-0432.22459914.v1
Autor:
W. Michael Korn, Sanaa Tahiri, Regina Linetskaya, Ryan Courtin, Sharvina Ziyeh, Anna Ong, Elizabeth Dito, Alan P. Venook, R. Kate Kelley, Eric A. Collisson, Margaret A. Tempero, Peter Kuhn, AmirAli Talasaz, Nancy M. Joseph, Olga M. Mirzoeva, Jessica Van Ziffle, Tanios Bekaii-Saab, Andrew H. Ko
Supplemental figure 1. Abdominal CT scans from a patient who achieved minor response following 2 cycles of treatment. Representative sections from baseline (left) and on-treatment (right) scans are shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f36492a194cf605b505dc14b2c73725
https://doi.org/10.1158/1078-0432.22459920.v1
https://doi.org/10.1158/1078-0432.22459920.v1
Autor:
W. Michael Korn, Sanaa Tahiri, Regina Linetskaya, Ryan Courtin, Sharvina Ziyeh, Anna Ong, Elizabeth Dito, Alan P. Venook, R. Kate Kelley, Eric A. Collisson, Margaret A. Tempero, Peter Kuhn, AmirAli Talasaz, Nancy M. Joseph, Olga M. Mirzoeva, Jessica Van Ziffle, Tanios Bekaii-Saab, Andrew H. Ko
Purpose: On the basis of preclinical evidence of synergistic activity between MEK and EGFR inhibitors in pancreatic ductal adenocarcinoma (PDAC), we evaluated the safety and efficacy of selumetinib, a MEK1/2 inhibitor, plus erlotinib in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c150d61e444e1d4c5806c0617b36149
https://doi.org/10.1158/1078-0432.c.6524340.v1
https://doi.org/10.1158/1078-0432.c.6524340.v1
Autor:
W. Michael Korn, Sanaa Tahiri, Regina Linetskaya, Ryan Courtin, Sharvina Ziyeh, Anna Ong, Elizabeth Dito, Alan P. Venook, R. Kate Kelley, Eric A. Collisson, Margaret A. Tempero, Peter Kuhn, AmirAli Talasaz, Nancy M. Joseph, Olga M. Mirzoeva, Jessica Van Ziffle, Tanios Bekaii-Saab, Andrew H. Ko
Supplemental figure 2. Distribution of proportion of E-cadherin expressing tumor cells across all cases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f941dd6998462a78f3a157d69c60ce1
https://doi.org/10.1158/1078-0432.22459917
https://doi.org/10.1158/1078-0432.22459917
Autor:
Nancy M. Joseph, Annika Blank, Alan H. Shain, Ryan M. Gill, Sarah E. Umetsu, Nafis Shafizadeh, Michael S. Torbenson, Sanjay Kakar
Publikováno v:
Human Pathology. 122:60-71
HNF1A-inactivated hepatocellular adenomas (H-HCA) show steatosis, no atypia and loss of liver fatty acid binding protein (LFABP). LFABP loss also occurs in hepatocellular carcinoma (HCC). This study examines 68 LFABP-negative tumors: 33 typical H-HCA
Autor:
Nicholas R. Ladwig, Gregory R. Bean, Melike Pekmezci, John Boscardin, Nancy M. Joseph, Nicole Therrien, Ankur R. Sangoi, Brian Piening, Venkatesh Rajamanickam, Matthew Galvin, Brady Bernard, Charles Zaloudek, Joseph T. Rabban, Karuna Garg, Sarah E. Umetsu
Publikováno v:
The American journal of surgical pathology.
Inflammatory myofibroblastic tumor (IMT) of the uterus is a rare mesenchymal tumor with largely benign behavior; however, a small subset demonstrate aggressive behavior. While clinicopathologic features have been previously associated with aggressive