Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nancy M. Hanley"'
Autor:
Jennifer L. Griggs, Liang Chi, Nancy M. Hanley, Michael Kohan, Karen Herbin-Davis, David J. Thomas, Kun Lu, Rebecca C. Fry, Karen D. Bradham
Publikováno v:
Environmental Pollution. 309:119753
Arsenic exposure has been reported to alter the gut microbiome in mice. Activity of the gut microbiome derived from fecal microbiota has been found to affect arsenic bioaccessibility in an in vitro gastrointestinal (GI) model. Only a few studies have
Autor:
Luke P. Naeher, Olorunfemi Adetona, William Kyle Martin, Stephen L. Rathbun, Jia-Sheng Wang, Sarah H. Warren, Nancy M. Hanley, Christopher D. Simpson, David M. DeMarini, Junfeng Zhang, Anna M. Adetona, Mike Paulsen
Publikováno v:
Inhalation toxicology. 31(2)
BACKGROUND: Wildland firefighters conducting prescribed burns are exposed to a complex mixture of pollutants, requiring an integrated measure of exposure. OBJECTIVE: We used urinary mutagenicity to assess if systemic exposure to mutagens are higher i
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 714:17-25
Benzo[a]pyrene (BP) and dibenzo[a,l]pyrene (DBP) are two polycyclic aromatic hydrocarbons (PAHs) that exhibit distinctly different mutagenicity and carcinogenicity profiles. Although some studies show that these PAHs produce unstable DNA adducts, con
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 692:19-25
The Salmonella mutagenicity assay can be performed using cells that are in different growth phases. Thus, the plate-incorporation assay involves plating stationary-phase cells with the mutagen, after which the cells undergo a brief lag phase and, con
Autor:
Nancy M. Hanley, Amy H. Herring, Ronna L. Chan, David M. DeMarini, Sally D. Perreault, Andrew F. Olshan, Patricia V. Basta, Thomas J. Luben
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 688:41-46
Background Environmental, lifestyle, and occupational exposures on semen quality have been investigated in epidemiological studies with inconsistent results. Genetic factors involved in toxicant activation and detoxification have been examined in rel
Autor:
Martin Case, Benjamin C. Blount, John L. Valentine, Teresa L. Leavens, Rex A. Pegram, Michael C. Madden, Sarah H. Warren, Nancy M. Hanley, David M. DeMarini, Lalith K. Silva
Publikováno v:
Toxicological Sciences. 99:432-445
Exposure to bromodichloromethane (BDCM), one of the most prevalent disinfection byproducts in drinking water, can occur via ingestion of water and by dermal absorption and inhalation during activities such as bathing and showering. The objectives of
Autor:
Alan H. Tennant, Ann M. Richard, David M. DeMarini, Rogelio Tornero-Velez, Andrew D. Kligerman, Kunihiro Funasaka, Avram Gold, Courtney A. Granville, Marina V. Evans, Matthew K. Ross, Nancy M. Hanley, Rachel D. Grindstaff
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 572:98-112
1,1-Dichloropropene (1,1-DCPe) is a contaminant of some source waters used to make drinking water. Because of this and the fact that no toxicological data were available for this compound, which is structurally similar to the rodent carcinogen 1,3-di
Autor:
Courtney A. Granville, Ann M. Richard, Paul Swartz, Nancy M. Hanley, David M. DeMarini, Bijit Kundu, Susan D. Richardson, Daniel T. Shaughnessy
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 554:335-350
Halonitromethanes (HNMs) are a recently identified class of disinfection by-products (DPBs) in drinking water that are mutagenic in Salmonella and potent inducers of DNA strand breaks in mammalian cells. Here we compared the mutagenic potencies of th
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 525:77-83
Nonsmoking women in Xuan Wei County, Yunnan Province, China who use smoky coal for cooking and heating in poorly ventilated homes have the highest lung cancer mortality rate in China, and their lung cancer is linked epidemiologically to their use of
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 429:261-267
Brominated trihalomethanes (THMs) are disinfection by-products present frequently in chlorinated drinking water. Brominated THMs are mutagenic in a variety of systems and are carcinogenic in rodents. The metabolism of brominated THMs is thought to in