Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nancy M. Gonzalez"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T cell stemness and exhaustion coexist as two key contrasting phenomena during chronic antigen stimulation, such as infection, transplant, cancer, and autoimmunity. T cell exhaustion refers to the progressive loss of effector function caused by chron
Externí odkaz:
https://doaj.org/article/4b738df90b3e4bb3b05d77928270a7c1
Autor:
Cheng J. Song, Zhang Li, Ummey Khalecha Bintha Ahmed, Sarah J. Bland, Alex Yashchenko, Shanrun Liu, Ernald J. Aloria, Jeremie M. Lever, Nancy M. Gonzalez, Marisa A. Bickel, Cory B. Giles, Constantin Georgescu, Jonathan D. Wren, Mark L. Lang, Etty N. Benveniste, Laurie E. Harrington, Leo Tsiokas, James F. George, Kenneth L. Jones, David K. Crossman, Anupam Agarwal, Michal Mrug, Bradley K. Yoder, Katharina Hopp, Kurt A. Zimmerman
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Inducible disruption of cilia-related genes in adult mice results in slowly progressive cystic disease, which can be greatly accelerated by renal injury. METHODS: To identify in an unbiased manner modifier cells that may be influencing th
Autor:
Stephanie G. Yi, Dawei Zou, Yixuan Wang, Wenhao Chen, Xian Chang Li, A. Osama Gaber, Guohua Wang, Nancy M. Gonzalez
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:1122-1132
BACKGOUND B cells contribute to chronic transplant rejection by producing donor-specific antibodies and promoting T cell response , but how these processes are regulated at the transcriptional level remains unclear. Herein, we investigate the role of
Autor:
Dustin Z. Revell, John Bassler, Juling Zhou, Jeremie M. Lever, Zhang Li, James F. George, Nancy M. Gonzalez, Ernald Jules G. Aloria, Bradley K. Yoder, Kurt A. Zimmerman, Michael R. Crowley, Addison Rains, Dan Shan, Michal Mrug, Cheng Jack Song, Etty N. Benveniste, David K. Crossman, Zhaoqi Yan
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Mutations affecting cilia proteins have an established role in renal cyst formation. In mice, the rate of cystogenesis is influenced by the age at which cilia dysfunction occurs and whether the kidney has been injured. Disruption of cilia
Autor:
Teresa Chacana, Phillip Chumley, Laurie E. Harrington, Kurt A. Zimmerman, Michal Mrug, Nancy M. Gonzalez, Bradley K. Yoder
Publikováno v:
Physiological Reports
Several innate immune response components were recognized as outcome predictors in autosomal dominant polycystic kidney disease (ADPKD) and their causative role in disease pathogenesis was confirmed in animal models. In contrast, the role of adaptive