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pro vyhledávání: '"Nancy M. Archin"'
Autor:
David M. Margolis, Nancy M. Archin
Publikováno v:
Infectious Disorders - Drug Targets. 6:369-376
The therapeutic armamentarium for human immunodeficiency virus type 1 (HIV-1) infection continues to expand. New targets such as entry and integration have recently been successfully exploited. However, HIV-infected patients in need of treatment are
Autor:
Sally S. Atherton, Nancy M Archin
Publikováno v:
Journal of Neurovirology. 8:122-135
Following uniocular anterior chamber (AC) inoculation of BALB/c mice with the KOS strain of herpes simplex virus type 1 (HSV-1), virus spreads from the injected eye to the ipsilateral suprachiasmatic nucleus (SCN) in the central nervous system (CNS)
Autor:
Rosalie Bateson, John M. Coffin, Manoj K. Tripathy, Amanda M. Crooks, Joseph J. Eron, Angela D. M. Kashuba, Joann D. Kuruc, Douglas D. Richman, Elizabeth M. Anderson, Noelle P. Dahl, Kuo Hsiung Yang, Ronald J. Bosch, Matthew C. Strain, Mary F. Kearney, Kevin Robertson, Daria J. Hazuda, Nancy M. Archin, David M. Margolis
Publikováno v:
Archin, Nancy M; Bateson, Rosalie; Tripathy, Manoj K; Crooks, Amanda M; Yang, Kuo-Hsiung; Dahl, Noelle P; et al.(2014). HIV-1 expression within resting CD4+ T cells after multiple doses of vorinostat.. The Journal of infectious diseases, 210(5), 728-735. doi: 10.1093/infdis/jiu155. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/0rd3381n
The Journal of infectious diseases, vol 210, iss 5
The Journal of infectious diseases, vol 210, iss 5
Effective antiretroviral therapy allows human immunodeficiency virus (HIV)–infected individuals to live long and productive lives [1]. However, HIV infection remains incurable in part owing to the presence of quiescent, replication-competent provir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f635b38eb9547e9df8d39e8322a0ef8e
http://www.escholarship.org/uc/item/0rd3381n
http://www.escholarship.org/uc/item/0rd3381n
Autor:
Paul W. Denton, Rikke Olesen, J. Victor Garcia, Morgan Chateau, Tomonori Nochi, Shailesh K. Choudhary, David M. Margolis, Angela Wahl, Michael D. Swanson, John F. Krisko, Rae Ann Spagnuolo, Nancy M. Archin
Publikováno v:
Denton, P W, Olesen, R, Choudhary, S K, Archin, N M, Wahl, A, Swanson, M D, Chateau, M, Nochi, T, Krisko, J F, Spagnuolo, R A, Margolis, D M & Garcia, J V 2012, ' Generation of HIV latency in humanized BLT mice ', Journal of Virology, vol. 86, no. 1, pp. 630-4 . https://doi.org/10.1128/JVI.06120-11
Here we demonstrate that a combination of tenofovir, emtricitabine, and raltegravir effectively suppresses peripheral and systemic HIV replication in humanized BLT mice. We also demonstrate that antiretroviral therapy (ART)-treated humanized BLT mice
Autor:
Nancy M, Archin, David M, Margolis
Publikováno v:
Current opinion in HIV and AIDS. 1(2)
The persistence of small population integrated proviral HIV genomes capable of expressing HIV within long-lived CD4 T cells is a fundamental obstacle to the eradication or cure of HIV infection. As potent antiretroviral therapy by itself appears to b
Autor:
John L. Schmitz, Ann Wiegand, Anne Hartmann-Duff, Alan L. Landay, Nicholas Bandarenko, David M. Margolis, Sarah Palmer, Ronald J. Bosch, John M. Coffin, Joseph J. Eron, Nancy M. Archin, Jeffery A Martinson
Valproic acid and intensified antiretroviral therapy may deplete resting CD4+ T-cell HIV infection. We tested the ability of valproic acid to deplete resting CD4+ T-cell infection in patients receiving standard antiretroviral therapy.Resting CD4+ T-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2868a9c5086a607cefc302f4c25ddc50
https://europepmc.org/articles/PMC3863687/
https://europepmc.org/articles/PMC3863687/
Publikováno v:
The Journal of infectious diseases. 197(8)
Novel therapeutic approaches are needed to attack persistent proviral human immunodeficiency type 1 (HIV-1) infection. Hexamethylbisacetamide (HMBA) a hybrid bipolar compound induces expression of the HIV-1 promoter in the long terminal repeat (LTR)
Hexamethylbisacetamide (HMBA) induces human immunodeficiency virus type 1 (HIV-1) gene expression in latently infected T-cell and monocytoid cell lines. We find that HMBA activation of viral expression is Tat independent but, like Tat, increases the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5bee8a6c156eead81479aa08aa10ef5
Autor:
Julia M Hilliard, Lennard van den Boom, Sally S. Atherton, Nancy M Archin, Ludmila Perelygina
Publikováno v:
Investigative ophthalmologyvisual science. 44(7)
Purpose The timing of T-cell infiltration of the hypothalamus is crucial in the prevention of bilateral retinitis in mice inoculated with HSV-1 through the anterior chamber (AC). In H129-infected mice, T-cells are recruited to the suprachiasmatic nuc
Autor:
Nancy M Archin, Sally S. Atherton
Publikováno v:
Journal of neuroimmunology. 130(1-2)
Following anterior chamber (AC) inoculation of BALB/c mice with the KOS strain of herpes simplex virus type 1 (HSV-1), or with H129, a neuroinvasive and neurovirulent strain of HSV-1, both strains of virus spread from the injected eye through the bra