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Autor:
Chang Yub Kim, Beom Seop Rho, Carolina Vasquez, Brent W. Segelke, Katherine A. Kantardjieff, Bernhard Rupp, Nancy M Warfel, Thomas C. Terwilliger, Peter Castro, Timothy Lekin
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 61(Pt 4)
The Mycobacterium tuberculosis pyrR gene (Rv1379) encodes a protein that regulates the expression of pyrimidine-nucleotide biosynthesis (pyr) genes in a UMP-dependent manner. Because pyrimidine biosynthesis is an essential step in the progression of