Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nancy Luckashenak"'
Autor:
Susanne Stutte, Axel Imhof, Diana Dudziak, Sebastian Hogl, Thomas Brocker, Cord Brakebusch, Nancy Luckashenak, Céline Leroy, Ignasi Forné, Anna M. Schulz, Stefan F. Lichtenthaler, Stephan A. Müller
Publikováno v:
The Journal of Cell Biology
The journal of cell biology 211(3), 553-567 (2015). doi:10.1083/jcb.201503128
The journal of cell biology 211(3), 553-567 (2015). doi:10.1083/jcb.201503128
Cdc42 control of actin dynamics keeps DCs in an immature state, and loss of Cdc42 activity facilitates secretion and rapid up-regulation of intracellular molecules to the cell surface, which shows that Cdc42 contributes to DC immunogenicity by regula
Autor:
Jeroen J.M. Hoozemans, Jaap Goudsmit, Hanna Inganäs, Başak Kükrer, Kiana West, Imke Sprengers, Xinyi Li, Michelle Wagner, Heng Zhang, Carrie Arnold, Lucy Chammas, Elissa Keogh, Frederique Bard, Wouter Koudstaal, Veronica Moreno, Julie Kim, Tariq Nahar, Gabriel Pascual, Gerrard Perdok, Laura A. N. Peferoen, Jeroen van Ameijde, Xueyong Zhu, Els C Brinkman van der Linden, Trevin Holland, Jehangir Wadia, Nancy Luckashenak, Zara Fulton, Martha Costa, Martin Koldijk, Berdien Siregar, Lauren Fletcher, R. Anthony Williamson, Adrian Apetri, Wenli Yu, Ian A. Wilson, Otto Diefenbach
Publikováno v:
Pascual, G, Wadia, J S, Zhu, X, Keogh, E, Kükrer, B, van Ameijde, J, Inganäs, H, Siregar, B, Perdok, G, Diefenbach, O, Nahar, T, Sprengers, I, Koldijk, M H, der Linden, E C B V, Peferoen, L A, Zhang, H, Yu, W, Li, X, Wagner, M, Moreno, V, Kim, J, Costa, M, West, K, Fulton, Z, Chammas, L, Luckashenak, N, Fletcher, L, Holland, T, Arnold, C, Anthony Williamson, R, Hoozemans, J J, Apetri, A, Bard, F, Wilson, I A, Koudstaal, W & Goudsmit, J 2017, ' Immunological memory to hyperphosphorylated tau in asymptomatic individuals ', Acta Neuropathologica, vol. 133, no. 5, pp. 767-783 . https://doi.org/10.1007/s00401-017-1705-y
Acta Neuropathologica
Acta neuropathologica, 133(5), 767-783. Springer Verlag
Acta Neuropathologica, 133(5), 767-783. Springer Verlag
Acta Neuropathologica
Acta neuropathologica, 133(5), 767-783. Springer Verlag
Acta Neuropathologica, 133(5), 767-783. Springer Verlag
Several reports have described the presence of antibodies against Alzheimer’s disease-associated hyperphosphorylated forms of tau in serum of healthy individuals. To characterize the specificities that can be found, we interrogated peripheral IgG+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0dd5aca2d919eb046a2d3d9e6c9b9b
https://research.vumc.nl/en/publications/c1c61a6a-74cf-4ea9-b3c5-e6a59cbe6284
https://research.vumc.nl/en/publications/c1c61a6a-74cf-4ea9-b3c5-e6a59cbe6284
Autor:
Laurence C. Eisenlohr, Michael A. Miller, Gomathinayagam Sinnathamby, Sébastien Apcher, Nancy Luckashenak
Publikováno v:
Immunologic Research. 51:237-248
CD4+ T cells (T(CD4+)) are activated by peptides, generally 13-17 amino acids in length, presented at the cell surface in combination with highly polymorphic MHC class II molecules. According to the classical model, these peptides are generated by en
Publikováno v:
Journal of Leukocyte Biology. 83:419-429
Intracellular signaling initiated by ligation of the TCR influences cell fate at multiple points during the lifespan of a T cell. This is especially evident during thymic selection, where the nature of TCR-dependent signaling helps to establish a MHC
Autor:
Nancy Luckashenak, Asha Purnima Veerappan Ganesan, Laurence C. Eisenlohr, Michael A. Miller, Mark Mendonca
Publikováno v:
Nature medicine. 21(10)
By convention, CD4+ T lymphocytes recognize foreign and self peptides derived from internalized antigens in combination with major histocompatibility complex class II molecules. Alternative pathways of epitope production have been identified, but the
Publikováno v:
The Journal of Immunology. 177:5177-5185
The Src homology 2 domain-containing leukocyte protein of 76 kDa (SLP-76) is an important molecular intermediate in multiple signaling pathways governing immune cell function. In this study, we report that SLP-76 is expressed in CD11c+B220− dendrit
Autor:
Paola Allavena, Maria Libera Ascierto, Davide Bedognetti, Daniel W. Beury, Vincenzo Bronte, Sjoerd H. van der Burg, Zheng Cai, Margaret K. Callahan, Bruce D. Car, Gang Chen, Mariacristina Chioda, Olesya Chornoguz, Sandra Demaria, Jiehui Deng, Julie Y. Djeu, Sarah S. Donatelli, Charles G. Drake, Glenn Dranoff, Nicholas M. Durham, Laurence C. Eisenlohr, Leisha A. Emens, Benedetto Farsaci, Taylor Feehley, Paola Filipazzi, Maria Rosaria Galdiero, Gianfranco di Genova, Paul B. Gilman, Mark I. Greene, John W. Greiner, James L. Gulley, Claire Hearnden, James W. Hodge, Veronica Huber, Elizabeth M. Jaffee, Masahisa Jinushi, Richard Jove, Michael H. Kershaw, Robert Kiss, Ilona Kryczek, Richard A. Lake, Bradley W. Lash, Ed C. Lavelle, W. Joost Lesterhuis, Charles J. Link, Jing Liu, Nancy Luckashenak, Ravi A. Madan, Laura Mandik-Nayak, Susanna Mandruzzato, Alberto Mantovani, Ilaria Marigo, Francesco M. Marincola, Veronique Mathieu, Kenneth F. May, Andrew L. Mellor, Lauren M.F. Merlo, Richard Metz, Simone Mocellin, Richard A. Morgan, Alexander J. Muller, David H. Munn, Yasuhiro Nagai, Cathryn Nagler, Amanda Norvell, Anna K. Nowak, Takuya Ohtani, Suzanne Ostrand-Rosenberg, Christian H. Ottensmeier, Claudia Palena, Katherine H. Parker, Michael A. Postow, George C. Prendergast, Saul J. Priceman, Jenni Punt, Gabriel A. Rabinovich, W. Jay Ramsey, Licia Rivoltini, Gabriela R. Rossi, Eva Sahakian, Arabinda Samanta, Marimo Sato-Matsushita, Natalia Savelyeva, Jeffrey Schlom, Antonio Sica, Pratima Sinha, Courtney Smith, Mark J. Smyth, Eduardo M. Sotomayor, Freda K. Stevenson, Victoria Sundblad, Michele W.L. Teng, Kwong-Yok Tsang, Hiromichi Tsuchiya, Nicholas N. Vahanian, Alejandro Villagra, Ena Wang, Lin Wang, Shuang Wei, Marij J.P. Welters, Richard A. Westhouse, Karrune Woan, Jedd D. Wolchok, Hua Yu, Hongtao Zhang, Ende Zhao, Zhiqiang Zhu, Weiping Zou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b807bf84db819ee5e167d60e787f2608
https://doi.org/10.1016/b978-0-12-394296-8.01002-2
https://doi.org/10.1016/b978-0-12-394296-8.01002-2
Dendritic cells are the most potent antigen-presenting cells in vivo, capable of both the initiation of a primary immune response and the induction of tolerance. Dendritic cells display considerable heterogeneity, both with respect to the subsets tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b395d64058e5e54cc0ccd1b7b49ad0d6
https://doi.org/10.1016/b978-0-12-394296-8.00005-1
https://doi.org/10.1016/b978-0-12-394296-8.00005-1
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 190(1)
Epidermal Langerhans cells (LCs) of the skin represent the prototype migratory dendritic cell (DC) subtype. In the skin, they take up Ag, migrate to the draining lymph nodes, and contribute to Ag transport and immunity. Different depletion models for
Autor:
James L. Clements, Nancy Luckashenak
Publikováno v:
Frontiers in bioscience : a journal and virtual library. 12
Antigen receptors and integrins are structurally and functionally distinct, but both play key roles in regulating immune cell activation and function. Understanding the molecular basis of the signaling pathways utilized by antigen receptors and integ