Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Nancy Lan"'
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract Emerging studies underscore the promising capabilities of large language model-based chatbots in conducting basic bioinformatics data analyses. The recent feature of accepting image inputs by ChatGPT, also known as GPT-4V(ision), motivated u
Externí odkaz:
https://doaj.org/article/cc7780b7c6b740e9aa6aa39d2bcfe68b
Autor:
Nairrita Majumder, Vishal Deepak, Sarah Hadique, Drake Aesoph, Murugesan Velayutham, Qing Ye, Md Habibul Hasan Mazumder, Sara E. Lewis, Vamsi Kodali, Anthony Roohollahi, Nancy Lan Guo, Gangqing Hu, Valery V. Khramtsov, Richard J. Johnson, Sijin Wen, Eric E. Kelley, Salik Hussain
Publikováno v:
Redox Biology, Vol 56, Iss , Pp 102465- (2022)
Background: The pathophysiologic significance of redox imbalance is unquestionable as numerous reports and topic reviews indicate alterations in redox parameters during corona virus disease 2019 (COVID-19). However, a more comprehensive understanding
Externí odkaz:
https://doaj.org/article/01e25e2738ba45f8b17b9d63b67feab4
Autor:
Qing Ye, Rebecca A. Raese, Dajie Luo, Juan Feng, Wenjun Xin, Chunlin Dong, Yong Qian, Nancy Lan Guo
Publikováno v:
Cells, Vol 12, Iss 14, p 1917 (2023)
Breast cancer treatment can be improved with biomarkers for early detection and individualized therapy. A set of 86 microRNAs (miRNAs) were identified to separate breast cancer tumors from normal breast tissues (n = 52) with an overall accuracy of 90
Externí odkaz:
https://doaj.org/article/fc72628e8e484ff1b901f90b1c8bc293
Autor:
Qing Ye, Nancy Lan Guo
Publikováno v:
Cells, Vol 12, Iss 1, p 101 (2022)
There are insufficient accurate biomarkers and effective therapeutic targets in current cancer treatment. Multi-omics regulatory networks in patient bulk tumors and single cells can shed light on molecular disease mechanisms. Integration of multi-omi
Externí odkaz:
https://doaj.org/article/3cea653ba86e4715b009e7d28927bfd8
Autor:
Qing Ye, Nancy Lan Guo
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1782 (2022)
There are currently no accurate biomarkers for optimal treatment selection in early-stage non-small cell lung cancer (NSCLC). Novel therapeutic targets are needed to improve NSCLC survival outcomes. This study systematically evaluated the association
Externí odkaz:
https://doaj.org/article/1d783a73f6c94235b1e73827d5e9cfad
Autor:
Nancy Lan Guo, Afshin Dowlati, Rebecca A. Raese, Chunlin Dong, Guoan Chen, David G. Beer, Justine Shaffer, Salvi Singh, Ujala Bokhary, Lin Liu, John Howington, Thomas Hensing, Yong Qian
Publikováno v:
EBioMedicine, Vol 32, Iss , Pp 102-110 (2018)
Purpose: This study aims to develop a multi-gene assay predictive of the clinical benefits of chemotherapy in non-small cell lung cancer (NSCLC) patients, and substantiate their protein expression as potential therapeutic targets. Patients and method
Externí odkaz:
https://doaj.org/article/92c05a4368574b7ca60a3108e3bbfb84
Autor:
Joseph Putila, Nancy Lan Guo
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100994 (2014)
Accurate assessment of a patient's risk of recurrence and treatment response is an important prerequisite of personalized therapy in lung cancer. This study extends a previously described non-small cell lung cancer prognostic model by the addition of
Externí odkaz:
https://doaj.org/article/81c2b6bc1e4440018b4de26f69aed807
Autor:
Nancy Lan Guo, Ying-Wooi Wan
Publikováno v:
Cancer Informatics, Vol 13s5 (2014)
Unraveling complex molecular interactions and networks and incorporating clinical information in modeling will present a paradigm shift in molecular medicine. Embedding biological relevance via modeling molecular networks and pathways has become incr
Externí odkaz:
https://doaj.org/article/0e0cef11550548cba978a5133a7fc0ee
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17493 (2011)
In the treatment of lung cancer, an accurate estimation of patient clinical outcome is essential for choosing an appropriate course of therapy. It is important to develop a prognostic stratification model which combines clinical, pathological and dem
Externí odkaz:
https://doaj.org/article/d9d46e680fda48098d5f396a8ee70bbb
Publikováno v:
PLoS ONE, Vol 6, Iss 3 (2011)
Externí odkaz:
https://doaj.org/article/a3d188eba8c1491b92aebee59418e1af