Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nancy L. Wu"'
Publikováno v:
Biochemical and biophysical research communications. 571
Rats have long been an ideal model for disease research in the field of biomedicine, but the bottleneck of in vitro culture of rat embryonic stem (ES) cells hindered the wide application as genetic disease models. Here, we optimized a special medium
Autor:
Ying Liu, Baruch Frenkel, Malcolm C. Pike, Robert E. Maxson, Hai-Yun Yen, Nancy L. Wu, Yankel Gabet, Anthony Martin, Louis Dubeau
Publikováno v:
Laboratory Investigation. 92:802-811
Incessant menstrual cycle activity, uninterrupted by either pregnancy or oral contraceptive use, is the most important risk factor for sporadic ovarian cancer. Menstrual cycle progression is partly controlled by steroid hormones such as estrogens and
Autor:
Jingjing Sun, Robert E. Maxson, Youzhen Yen, Nancy L. Wu, Man-Chun Ting, Paul G. Roybal, Liqiong Liu
Publikováno v:
Development. 136:855-864
Heterozygous loss of Twist1 function causes coronal synostosis in both mice and humans. We showed previously that in mice this phenotype is associated with a defect in the neural crest-mesoderm boundary within the coronal suture, as well as with a re
Publikováno v:
Nature
The use of homologous recombination to modify genes in embryonic stem (ES) cells provides a powerful means to elucidate gene function and create disease models1. Application of this technology to engineer genes in rats has previously been impossible
Autor:
Christopher A. Schafer, Jingjing Sun, Robert E. Maxson, Nancy L. Wu, Paul G. Roybal, Man-Chun Ting
Publikováno v:
Developmental Biology. (1-2):28-39
In an effort to understand the morphogenetic forces that shape the bones of the skull, we inactivated Msx1 and Msx2 conditionally in neural crest. We show that Wnt1-Cre inactivation of up to three Msx1/2 alleles results in a progressively larger defe