Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Nancy L. Cardwell"'
Autor:
Rei Ukita, Wei Kelly Wu, Jiancong Liang, Jennifer R. Talackine, Yatrik J. Patel, Sean A. Francois, Nancy L. Cardwell, Charles R. Flynn, Alexandra Shingina, Mary Kay Washington, Vincent Quoc-Huy Trinh, Matthew Bacchetta, Sophoclis P. Alexopoulos
Publikováno v:
Journal of Applied Physiology. 134:840-845
We present here a large animal platform for congestive hepatopathy, a disease growing in clinical prevalence due to the increasing number of Fontan-palliated patients. Further data are needed to develop a better clinical management strategy for this
Autor:
Wei K. Wu, Matthew T. Stier, John W. Stokes, Rei Ukita, Yatrik J. Patel, Michael Cortelli, Stuart R. Landstreet, Jennifer R. Talackine, Nancy L. Cardwell, Elizabeth M. Simonds, Meredith Mentz, Cindy Lowe, Clayne Benson, Caitlin T. Demarest, Sophoclis P. Alexopoulos, Ciara M. Shaver, Matthew Bacchetta
Publikováno v:
Science Advances. 9
Improved approaches to expanding the pool of donor lungs suitable for transplantation are critically needed for the growing population with end-stage lung disease. Cross-circulation (XC) of whole blood between swine and explanted human lungs has prev
Autor:
Wei Kelly Wu, Rei Ukita, Yatrik J. Patel, Michael Cortelli, Vincent Q. Trinh, Ioannis A. Ziogas, Sean A. Francois, Meredith Mentz, Nancy L. Cardwell, Jennifer R. Talackine, William M. Grogan, John W. Stokes, Youngmin A. Lee, Jinho Kim, Sophoclis P. Alexopoulos, Matthew Bacchetta
Publikováno v:
Hepatology.
Autor:
John W. Stokes, Matthew Bacchetta, Gordana Vunjak-Novakovic, Clayne Benson, Jennifer Talackine, Jonathan A. Reimer, Sophoclis P. Alexopoulos, John D. O’Neill, Michael J. Lee, Charles R. Flynn, Rei Ukita, Ahmed E. Hozain, Andrew Tumen, Nancy L. Cardwell, Meghan R. Pinezich, Wei Kelly Wu
Publikováno v:
ASAIO J
Although machine perfusion has gained momentum as an organ preservation technique in liver transplantation, persistent organ shortages and high waitlist mortality highlight unmet needs for improved organ salvage strategies. Beyond preservation, extra
Autor:
W. Kelly Wu, Brandon A. Guenthart, John D. O'Neill, Ahmed E. Hozain, Yuliya Tipograf, Rei Ukita, John W. Stokes, Yatrik J. Patel, Meghan Pinezich, Jennifer R. Talackine, Nancy L. Cardwell, Kenmond Fung, Gordana Vunjak-Novakovic, Matthew Bacchetta
Publikováno v:
J Heart Lung Transplant
BACKGROUND: Xenogeneic cross-circulation (XC) is an experimental method for ex vivo organ support and recovery that could expand the pool of donor lungs suitable for transplantation. The objective of this study was to establish and validate a standar
Autor:
Keith E. Cook, Nancy L. Cardwell, Erika B. Rosenzweig, Rachel Donocoff, Jennifer Talackine, Rei Ukita, Andrew Tumen, Neal M. Foley, John W. Stokes, Yuliya Tipograf, Matthew Bacchetta
Publikováno v:
ASAIO J
Pulmonary hypertension (PH) is a progressive disease that leads to cardiopulmonary dysfunction and right heart failure from pressure and volume overloading of the right ventricle (RV). Mechanical cardiopulmonary support has theoretical promise as a b
Autor:
Prarthana Patil, Katherine A. Russo, Joshua T. McCune, Alonda C. Pollins, Matthew A. Cottam, Bryan R. Dollinger, Carlisle R. DeJulius, Mukesh K. Gupta, Richard D’Arcy, Juan M. Colazo, Fang Yu, Mariah G. Bezold, John R. Martin, Nancy L. Cardwell, Jeffrey M. Davidson, Callie M. Thompson, Adrian Barbul, Alyssa H. Hasty, Scott A. Guelcher, Craig L. Duvall
Publikováno v:
Sci Transl Med
Porous, resorbable biomaterials can serve as temporary scaffolds that support cell infiltration, tissue formation, and remodeling of nonhealing skin wounds. Synthetic biomaterials are less expensive to manufacture than biologic dressings and can achi
Autor:
Nancy L. Cardwell, Salam K. Kassis, Kianna R. Jackson, Patrick E. Assi, Alonda C. Pollins, Wesley P. Thayer
Publikováno v:
Burns. 46:1114-1119
Partial burn injury in older patients is associated with higher rates of morbidity, mortality, and conversion to full thickness burn (Finnerty et al., 2009; Pham et al., 2009). Both human and mouse models demonstrate an altered systemic immune respon
Autor:
Andrew Tumen, Rei Ukita, Kenmond Fung, Jinho Kim, Ya-Wen Chen, Jonathan A. Reimer, Brandon A. Guenthart, Ahmed E. Hozain, Rachel Donocoff, Edward C. Ruiz, Katherine M. Cunningham, Hans-Willem Snoeck, Nancy L. Cardwell, Michael T. Simpson, Dawn Queen, Alexander Romanov, Meghan R. Pinezich, Yuliya Tipograf, Charles C. Marboe, John W. Stokes, Jennifer Talackine, John D. O’Neill, Matthew Bacchetta, Adam Griesemer, Gordana Vunjak-Novakovic
Publikováno v:
Nature Medicine. 26:1102-1113
Patients awaiting lung transplantation face high wait-list mortality, as injury precludes the use of most donor lungs. Although ex vivo lung perfusion (EVLP) is able to recover marginal quality donor lungs, extension of normothermic support beyond 6
Autor:
Erika B. Rosenzweig, Caitlin T. Demarest, Yatrik Patel, Emily J Tsai, Rei Ukita, Jennifer Talackine, John W. Stokes, Matthew Bacchetta, Nancy L. Cardwell, Clayne Benson, Keith E. Cook, W Kelly Wu
Publikováno v:
J Vis Exp
Decompensated right ventricular failure (RVF) in pulmonary hypertension (PH) is fatal, with limited medical treatment options. Developing and testing novel therapeutics for PH requires a clinically relevant large animal model of increased pulmonary v