Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Nancy L. Buechler"'
Autor:
Nadeem Wajih, Swati Basu, Anuj Jailwala, Hee Won Kim, David Ostrowski, Andreas Perlegas, Crystal A. Bolden, Nancy L. Buechler, Mark T. Gladwin, David L. Caudell, Elaheh Rahbar, Martha A. Alexander-Miller, Vidula Vachharajani, Daniel B. Kim-Shapiro
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 1026-1039 (2017)
Sickle cell disease is caused by a mutant form of hemoglobin that polymerizes under hypoxic conditions, increasing rigidity, fragility, calcium influx-mediated dehydration, and adhesivity of red blood cells. Increased red cell fragility results in he
Externí odkaz:
https://doaj.org/article/6cbd35867bd04e4cafdee1f7691998b9
Autor:
Xianfeng Wang, Nancy L Buechler, Ayana Martin, Jonathan Wells, Barbara Yoza, Charles E McCall, Vidula Vachharajani
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160431 (2016)
OBJECTIVE:Obesity increases morbidity and resource utilization in sepsis patients. Sepsis transitions from early/hyper-inflammatory to late/hypo-inflammatory phase. Majority of sepsis-mortality occurs during the late sepsis; no therapies exist to tre
Externí odkaz:
https://doaj.org/article/8e294c943f174df684a956a65e2c53c4
Autor:
Xianfeng Wang, Nancy L Buechler, Ayana Martin, Jonathan Wells, Barbara Yoza, Charles E McCall, Vidula Vachharajani
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162560 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0160431.].
Externí odkaz:
https://doaj.org/article/f4019b525ba245af8a556f778d97ca40
Autor:
Xianfeng Wang, Nancy L. Buechler, Alan G. Woodruff, David L. Long, Manal Zabalawi, Barbara K. Yoza, Charles E. McCall, Vidula Vachharajani
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2738 (2018)
Sepsis and septic shock are the leading causes of death in non-coronary intensive care units worldwide. During sepsis-associated immune dysfunction, the early/hyper-inflammatory phase transitions to a late/hypo-inflammatory phase as sepsis progresses
Externí odkaz:
https://doaj.org/article/b96f38a9386c43b0b5f9eab1754900fc
Autor:
Xuewei Zhu, Cristina M. Furdui, Matthew A. Quinn, Peter W. Stacpoole, Ellen E. Quillen, Nancy L. Buechler, John S. Parks, Charles E. McCall, Jennifer Martinez, Manal Zabalawi, David L. Long, Rabina Mainali, Chia-Chi C. Key
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Dramatic metabolic reprogramming between an anabolic resistance and catabolic tol-erance state occurs within the immune system in response to systemic infection with the sepsis syndrome. While metabolic tissues such as the liver are subject to end-or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076a20fa5335306b23886b95e0365e8b
https://elifesciences.org/articles/64611
https://elifesciences.org/articles/64611
Autor:
Rabina Mainali, John S. Parks, Jennifer Martinez, Manal Zabalawi, Peter W. Stacpoole, Cristina M. Furdui, Chia-Chi C. Key, Ellen E. Quillen, Charles E. McCall, Nancy L. Buechler, Xuewei Zhu, David L. Long, Matthew A. Quinn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e2ef38b4119bdb506d453ffaf23b883
https://doi.org/10.7554/elife.64611.sa2
https://doi.org/10.7554/elife.64611.sa2
Publikováno v:
Journal of Inflammation Research
XianFeng Wang,Nancy L Buechler,Barbara K Yoza, Charles E McCall,Vidula Vachharajani Department of Anesthesiology, Medicine and Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA Background: Morbid obesity increases the cost of care in cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f43eff82a8a65dfa63491a2025529b
http://europepmc.org/articles/PMC5063563
http://europepmc.org/articles/PMC5063563
Autor:
David L. Caudell, Nancy L. Buechler, Anuj Jailwala, Mark T. Gladwin, Vidula Vachharajani, Hee Won Kim, Daniel B. Kim-Shapiro, Andreas Perlegas, Martha A. Alexander-Miller, Elaheh Rahbar, Nadeem Wajih, Swati Basu, Crystal Bolden, David Ostrowski
Publikováno v:
Redox Biology, Vol 12, Iss, Pp 1026-1039 (2017)
Redox Biology
Redox Biology
Sickle cell disease is caused by a mutant form of hemoglobin that polymerizes under hypoxic conditions, increasing rigidity, fragility, calcium influx-mediated dehydration, and adhesivity of red blood cells. Increased red cell fragility results in he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e23db9f12510f732520f69af10d6e1
http://www.sciencedirect.com/science/article/pii/S2213231717302525
http://www.sciencedirect.com/science/article/pii/S2213231717302525
Autor:
Barbara K. Yoza, Cristina M. Furdui, Vidula Vachharajani, David L. Long, Nancy L. Buechler, Charles E. McCall, Xianfeng Wang
RATIONALE: Obesity increases morbidity and mortality in acute illnesses such as sepsis and septic shock. We showed previously that the early/hyper-inflammatory phase of sepsis is exaggerated in obese mice with sepsis; sirtuin 2 (SIRT2) modulates seps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340d333d9f3ebf0ab1d5c6051d83a1a1
https://europepmc.org/articles/PMC6380915/
https://europepmc.org/articles/PMC6380915/
Autor:
Charles E. McCall, Vidula Vachharajani, Manal Zabalawi, Mihai G. Netea, Nancy L. Buechler, Tie Fu Liu, Barbara K. Yoza, Peter W. Stacpoole, Rob J.W. Arts, David L. Long, Ayana Martin
Publikováno v:
Jci Insight, 3,
Jci Insight, 3, 15, pp.
Jci Insight, 3, 15, pp.
Limited understanding of the mechanisms responsible for life-threatening organ and immune failure hampers scientists' ability to design sepsis treatments. Pyruvate dehydrogenase kinase 1 (PDK1) is persistently expressed in immune-tolerant monocytes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11e20eff174b8a19c4280c8eda21df8
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/194752
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/194752