Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nancy L Carson"'
Autor:
Ricardo A Garcia, Mujing Yan, Debra Search, Rongan Zhang, Nancy L Carson, Carol S Ryan, Constance Smith-Monroy, Joanna Zheng, Jian Chen, Yan Kong, Huaping Tang, Samuel E Hellings, Judith Wardwell-Swanson, Joseph E Dinchuk, George C Psaltis, David A Gordon, Peter W Glunz, Peter S Gargalovic
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111385 (2014)
BACKGROUND: P2Y(6), a purinergic receptor for UDP, is enriched in atherosclerotic lesions and is implicated in pro-inflammatory responses of key vascular cell types and macrophages. Evidence for its involvement in atherogenesis, however, has been lac
Externí odkaz:
https://doaj.org/article/226e843b35fe4bc7b87247e99442f01e
Autor:
Ricardo A García, Debra J Search, John A Lupisella, Jacek Ostrowski, Bo Guan, Jian Chen, Wen-Pin Yang, Amy Truong, Aiqing He, Rongan Zhang, Mujing Yan, Samuel E Hellings, Peter S Gargalovic, Carol S Ryan, Linda M Watson, Robert A Langish, Petia A Shipkova, Nancy L Carson, Joseph R Taylor, Richard Yang, George C Psaltis, Thomas W Harrity, Jeffrey A Robl, David A Gordon
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e53192 (2013)
BACKGROUND: Chronic glucocorticoid excess has been linked to increased atherosclerosis and general cardiovascular risk in humans. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) increases active glucocorticoid levels within tissues by
Externí odkaz:
https://doaj.org/article/6bd68584051f4497b56fefb3bbb8522c
Autor:
Bruce R. Ito, Jeffrey H. Omens, Israel Ramirez-Sanchez, Moises Bustamante, Nancy L. Carson, Ricardo Garcia, Guillermo Ceballos, Francisco Villarreal, Alejandra Garate-Carrillo
Publikováno v:
The Journal of Physiology. 597:1805-1817
KEY POINTS Heart failure with preserved ejection fraction (HFpEF) is seen more frequently in older women; risk factors include age, hypertension and excess weight. No female animal models of early stage remodelling (pre-HFpEF) have examined the effec
Autor:
Moises Muratt Bustamante-Pozo, Rongan Zhang, Nancy L. Carson, Madeleine Héroux, Michel Bouvier, Jian Chen, David A. Gordon, Bruce R. Ito, Stéphane St.-Onge, Gayani Fernando, Marilyn Carrier, Francisco Villarreal, Zhaoqing Wang, Alejandra Garate-Carrillo, Carol S. Ryan, Jignesh Nagar, Jacek Ostrowski, John A. Lupisella, Ricardo Garcia, Shailesh Dudhgaonkar, Debra Search, Ellen K. Kick, Xiuying Ma, Ruth R. Wexler, Mei-Yin Hsu, Elizabeth A. Dierks, Nicholas R. Wurtz, John Allocco
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • MI leads to ischemic damage of myocardium and activation of inflammatory programs as part of the wound healing response. • Selective activation of FPR2 on macrophages potentiates key cellular activities that enab
Highlights • MI leads to ischemic damage of myocardium and activation of inflammatory programs as part of the wound healing response. • Selective activation of FPR2 on macrophages potentiates key cellular activities that enab
Autor:
John A. Lupisella, Kiyoshi Fujii, David A. Gordon, Mei-Yin Hsu, Toshikazu Yamaoka, Yasuchi Kohno, Kohei Ohata, Kosuke Tsuda, Kazuto Arakawa, Nancy L. Carson, Kazunori Fukuchi, Ruth R. Wexler, Francisco Villarreal, Ellen K. Kick, Junichi Ishiyama, Jacek Ostrowski, Shingo Matsushima, Hitomi Yamada, Yoshifumi Saito, Bruce R. Ito, Yoshikazu Asahina, Ricardo Garcia, Nicholas R. Wurtz
Publikováno v:
Journal of medicinal chemistry. 63(17)
Formyl peptide receptor 2 (FPR2) agonists can stimulate resolution of inflammation and may have utility for treatment of diseases caused by chronic inflammation, including heart failure. We report the discovery of a potent and selective FPR2 agonist
Autor:
Rongan Zhang, Gayani Fernando, Francisco Villarreal, Bruce R. Ito, Elizabeth A. Dierks, Nicholas R. Wurtz, Mei-Yin Hsu, Ricardo Garcia, John A. Lupisella, Y Kohno, Jacek Ostrowski, Carol S. Ryan, Nancy L. Carson, Zhaoqing Wang, Y Asahina
Publikováno v:
European Heart Journal. 40
Background/Introduction Dysregulated inflammation following myocardial infarction (MI) can lead to maladaptive infarct healing, myocardial damage and heart failure. Formyl peptide receptor 2 (FPR2) plays an important role in the ligand-dependent regu
Autor:
Jeffrey H. Omens, Ricardo Garcia, Guillermo Ceballos, Francisco Villarreal, Israel Ramirez-Sanchez, Moises Muratt Bustamante Pozo, Nancy L. Carson, Bruce R. Ito, Alejandra Garate Carrillo
Publikováno v:
The FASEB Journal. 33
Autor:
Ricardo Garcia, Guillermo Ceballos, Israel Ramirez-Sanchez, Moises Bustamante, Bruce R. Ito, Jeffrey H. Omens, Francisco Villarreal, Maria Loredo, Nancy L. Carson, Alejandra Garate-Carrillo
Publikováno v:
The FASEB Journal. 32
Autor:
Debra Search, Huaping Tang, Mujing Yan, Ricardo Garcia, Nancy L. Carson, Joseph E. Dinchuk, Constance Smith-Monroy, Yan Kong, Rongan Zhang, David A. Gordon, Jian Chen, Carol S. Ryan, Peter S. Gargalovic, George C. Psaltis, Judith Wardwell-Swanson, Joanna Zheng, Samuel Hellings, Peter W. Glunz
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111385 (2014)
PLoS ONE
PLoS ONE
BACKGROUND: P2Y(6), a purinergic receptor for UDP, is enriched in atherosclerotic lesions and is implicated in pro-inflammatory responses of key vascular cell types and macrophages. Evidence for its involvement in atherogenesis, however, has been lac
Autor:
Michael N. Oda, Nancy L. Carson, Gregory C. Shearer, Mark S. Borja, Xiaoqin Liu, Chongren Tang, Gayani Fernando, Franck Duclos, Lei Zhao, Bradley Hammerson, Madhu S. Budamagunta, Jacques Genest, Richard Yang
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71541 (2013)
PLoS ONE
PLoS ONE
High density lipoprotein (HDL) cholesterol levels are associated with decreased risk of cardiovascular disease, but not all HDL are functionally equivalent. A primary determinant of HDL functional status is the conformational adaptability of its main