Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Nancy Kleckner"'
Autor:
Emeline Dubois, Stéphanie Boisnard, Henri-Marc Bourbon, Kenza Yefsah, Karine Budin, Robert Debuchy, Liangran Zhang, Nancy Kleckner, Denise Zickler, Eric Espagne
Publikováno v:
PLoS Biology, Vol 22, Iss 7, p e3002705 (2024)
We show here that in the fungus Sordaria macrospora, the meiosis-specific HORMA-domain protein Hop1 is not essential for the basic early events of chromosome axis development, recombination initiation, or recombination-mediated homolog coalignment/pa
Externí odkaz:
https://doaj.org/article/c0151538ffce48b6aae48f506b11fcd1
Autor:
Mara Prentiss, Dianzhuo Wang, Jonathan Fu, Chantal Prévost, Veronica Godoy-Carter, Nancy Kleckner, Claudia Danilowicz
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0288611 (2023)
In E. coli, double strand breaks (DSBs) are resected and loaded with RecA protein. The genome is then rapidly searched for a sequence that is homologous to the DNA flanking the DSB. Mismatches in homologous partners are rare, suggesting that RecA sho
Externí odkaz:
https://doaj.org/article/1bcd6cbdcd8f43f0a1c3f713f1e07764
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Chromosome movement is prominent at mid-meiotic prophase and is proposed to enhance the efficiency and/or stringency of homolog pairing and/or to help prevent or resolve topological entanglements. Here, we combine fluorescent repressor operator syste
Externí odkaz:
https://doaj.org/article/d32a1535efb34e5f8ba30c547e1e90d8
Autor:
Eugene Gladyshev, Nancy Kleckner
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1006015 (2016)
Haploid germline nuclei of many filamentous fungi have the capacity to detect homologous nucleotide sequences present on the same or different chromosomes. Once recognized, such sequences can undergo cytosine methylation or cytosine-to-thymine mutati
Externí odkaz:
https://doaj.org/article/0bde23be5596434cbc2291c0d419df9e
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004042 (2014)
Crossing-over is a central feature of meiosis. Meiotic crossover (CO) sites are spatially patterned along chromosomes. CO-designation at one position disfavors subsequent CO-designation(s) nearby, as described by the classical phenomenon of CO interf
Externí odkaz:
https://doaj.org/article/0e1ba47b67014841b915fc9c40dd01bd
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75895 (2013)
Three-dimensional organization of the genome is important for regulation of gene expression and maintenance of genomic stability. It also defines, and is defined by, contacts between different chromosomal loci. Interactions between loci positioned on
Externí odkaz:
https://doaj.org/article/8d50d2fefa9f4764ab52ee1a1d9c0e31
Autor:
Jennifer J Wanat, Keun P Kim, Romain Koszul, Sarah Zanders, Beth Weiner, Nancy Kleckner, Eric Alani
Publikováno v:
PLoS Genetics, Vol 4, Iss 9, p e1000188 (2008)
Chromosome movements are a general feature of mid-prophase of meiosis. In budding yeast, meiotic chromosomes exhibit dynamic movements, led by nuclear envelope (NE)-associated telomeres, throughout the zygotene and pachytene stages. Zygotene motion u
Externí odkaz:
https://doaj.org/article/19dc025bf2984d4880d255c2a94f524c
RecA balances genomic stability and evolution using many successive mismatch tolerant homology tests
Autor:
Mara Prentiss, John Wang, Jonathan Fu, Chantal Prévost, Veronica Godoy-Carter, Nancy Kleckner, Claudia Danilowicz
A double-strand break (DSB) must usually be repaired with as little alteration to the genome as possible, though some rare alterations provide valuable genomic evolution. InE.coli, a DSB undergoes resection to give 3’ ssDNA tails. These invading st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88d04ead915d39e6408799edd552e54f
https://doi.org/10.1101/2022.12.09.519633
https://doi.org/10.1101/2022.12.09.519633
