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of 532
pro vyhledávání: '"Nancy Kleckner"'
Autor:
Emeline Dubois, Stéphanie Boisnard, Henri-Marc Bourbon, Kenza Yefsah, Karine Budin, Robert Debuchy, Liangran Zhang, Nancy Kleckner, Denise Zickler, Eric Espagne
Publikováno v:
PLoS Biology, Vol 22, Iss 7, p e3002705 (2024)
We show here that in the fungus Sordaria macrospora, the meiosis-specific HORMA-domain protein Hop1 is not essential for the basic early events of chromosome axis development, recombination initiation, or recombination-mediated homolog coalignment/pa
Externí odkaz:
https://doaj.org/article/c0151538ffce48b6aae48f506b11fcd1
Autor:
Mara Prentiss, Dianzhuo Wang, Jonathan Fu, Chantal Prévost, Veronica Godoy-Carter, Nancy Kleckner, Claudia Danilowicz
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0288611 (2023)
In E. coli, double strand breaks (DSBs) are resected and loaded with RecA protein. The genome is then rapidly searched for a sequence that is homologous to the DNA flanking the DSB. Mismatches in homologous partners are rare, suggesting that RecA sho
Externí odkaz:
https://doaj.org/article/1bcd6cbdcd8f43f0a1c3f713f1e07764
Akademický článek
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Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Chromosome movement is prominent at mid-meiotic prophase and is proposed to enhance the efficiency and/or stringency of homolog pairing and/or to help prevent or resolve topological entanglements. Here, we combine fluorescent repressor operator syste
Externí odkaz:
https://doaj.org/article/d32a1535efb34e5f8ba30c547e1e90d8
RecA balances genomic stability and evolution using many successive mismatch tolerant homology tests
Autor:
Mara Prentiss, John Wang, Jonathan Fu, Chantal Prévost, Veronica Godoy-Carter, Nancy Kleckner, Claudia Danilowicz
A double-strand break (DSB) must usually be repaired with as little alteration to the genome as possible, though some rare alterations provide valuable genomic evolution. InE.coli, a DSB undergoes resection to give 3’ ssDNA tails. These invading st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88d04ead915d39e6408799edd552e54f
https://doi.org/10.1101/2022.12.09.519633
https://doi.org/10.1101/2022.12.09.519633
Publikováno v:
Nature
Meiosis, although essential for reproduction, is also variable and error-prone: rates of chromosome crossover vary among gametes, between the sexes, and among humans of the same sex, and chromosome missegregation leads to abnormal chromosome numbers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61243da54d2586df5496033b0a37b3ef
https://europepmc.org/articles/PMC10032581/
https://europepmc.org/articles/PMC10032581/
Autor:
A. Paul Alivisatos, Justin C. Ondry, Maria V. Mukhina, Nancy Kleckner, Austin Akey, Jason S. Tresback
Publikováno v:
ACS nano, vol 15, iss 3
ACS Nano
ACS Nano
Mechanoluminescent materials, which emit light in response to elastic deformation, are demanded for use as in situ stress sensors. ZnS doped with Mn is known to exhibit one of the lowest reported thresholds for appearance of mechanoluminescence, with
Sister chromatids separate during anaphase in a three-stage program as directed by interaxis bridges
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(10)
During mitosis, from late prophase onward, sister chromatids are connected along their entire lengths by axis-linking chromatin/structure bridges. During prometaphase/metaphase, these bridges ensure that sister chromatids retain a parallel, paranemic