Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Nancy Kelley"'
Defluorination of Organofluorine Compounds Using Dehalogenase Enzymes from Delftia acidovorans (D4B)
Autor:
Sanaz Farajollahi, Nina V. Lombardo, Michael D. Crenshaw, Hao-Bo Guo, Megan E. Doherty, Tina R. Davison, Jordan J. Steel, Erin A. Almand, Vanessa A. Varaljay, Chia Suei-Hung, Peter A. Mirau, Rajiv J. Berry, Nancy Kelley-Loughnane, Patrick B. Dennis
Publikováno v:
ACS Omega, Vol 9, Iss 26, Pp 28546-28555 (2024)
Externí odkaz:
https://doaj.org/article/72b19a5b35734eb7bb1d808d21f7e091
Autor:
Claretta J. Sullivan, Kennedy Brown, Chia-Suei Hung, Joseph Kuo-Hsiang Tang, Mark DeSimone, Vincent Chen, Pamela F. Lloyd, Maneesh Gupta, Abby Juhl, Wendy Crookes-Goodson, Milana Vasudev, Patrick B. Dennis, Nancy Kelley-Loughnane
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Nature offers many examples of materials which exhibit exceptional properties due to hierarchical assembly of their constituents. In well-studied multi-cellular systems, such as the morpho butterfly, a visible indication of having ordered su
Externí odkaz:
https://doaj.org/article/8e5a5d221c8846c291a5d21e6e83c903
Autor:
Cassandra E. Gheorghe, Sarah-Jane Leigh, Gabriel S.S. Tofani, Thomaz F.S. Bastiaanssen, Joshua M. Lyte, Elisa Gardellin, Ashokkumar Govindan, Conall Strain, Sonia Martinez-Herrero, Michael S. Goodson, Nancy Kelley-Loughnane, John F. Cryan, Gerard Clarke
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114079- (2024)
Summary: Chronic stress disrupts microbiota-gut-brain axis function and is associated with altered tryptophan metabolism, impaired gut barrier function, and disrupted diurnal rhythms. However, little is known about the effects of acute stress on the
Externí odkaz:
https://doaj.org/article/2451a00d25244e4ea04d5c872d5038b9
Autor:
Hao-Bo Guo, Baxter Huntington, Alexander Perminov, Kenya Smith, Nicholas Hastings, Patrick Dennis, Nancy Kelley-Loughnane, Rajiv Berry
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0301866 (2024)
We use AlphaFold2 (AF2) to model the monomer and dimer structures of an intrinsically disordered protein (IDP), Nvjp-1, assisted by molecular dynamics (MD) simulations. We observe relatively rigid dimeric structures of Nvjp-1 when compared with the m
Externí odkaz:
https://doaj.org/article/416991bfccf24a2ca5f261e28ebb2987
Autor:
Hao-Bo Guo, Vanessa A. Varaljay, Gary Kedziora, Kimberly Taylor, Sanaz Farajollahi, Nina Lombardo, Eric Harper, Chia Hung, Marie Gross, Alexander Perminov, Patrick Dennis, Nancy Kelley-Loughnane, Rajiv Berry
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Despite the success of AlphaFold2 (AF2), it is unclear how AF2 models accommodate for ligand binding. Here, we start with a protein sequence from Acidimicrobiaceae TMED77 (T7RdhA) with potential for catalyzing the degradation of per- and pol
Externí odkaz:
https://doaj.org/article/431950e19a134e218e73e62dcc282d68
Autor:
Zhifeng Kuang, John Luginsland, Robert J. Thomas, Patrick B. Dennis, Nancy Kelley-Loughnane, William P. Roach, Rajesh R. Naik
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its current worldwide spread have caused a pandemic of acute respiratory disease COVID-19. The virus can result in mild to severe, and even to fatal respirator
Externí odkaz:
https://doaj.org/article/9b80fe0c0bcd4db8be553fa1ea39c8c3
Autor:
Hao-Bo Guo, Alexander Perminov, Selemon Bekele, Gary Kedziora, Sanaz Farajollahi, Vanessa Varaljay, Kevin Hinkle, Valeria Molinero, Konrad Meister, Chia Hung, Patrick Dennis, Nancy Kelley-Loughnane, Rajiv Berry
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract AlphaFold 2 (AF2) has placed Molecular Biology in a new era where we can visualize, analyze and interpret the structures and functions of all proteins solely from their primary sequences. We performed AF2 structure predictions for various pr
Externí odkaz:
https://doaj.org/article/4a27d885751d48129fa8912d727ea523
Autor:
Michael S. Goodson, Robyn A. Barbato, J. Philip Karl, Karl Indest, Nancy Kelley-Loughnane, Robert Kokoska, Camilla Mauzy, Kenneth Racicot, Vanessa Varaljay, Jason Soares
Publikováno v:
Environmental Microbiome, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract The Tri-Service Microbiome Consortium (TSMC) was founded to enhance collaboration, coordination, and communication of microbiome research among U.S. Department of Defense (DoD) organizations. The annual TSMC symposium is designed to enable i
Externí odkaz:
https://doaj.org/article/0e5722f1603445e786595691f57dfacb
Autor:
J. Philip Karl, Robyn A. Barbato, Laurel A. Doherty, Aarti Gautam, Sarah M. Glaven, Robert J. Kokoska, Dagmar Leary, Rebecca L. Mickol, Matthew A. Perisin, Andrew J. Hoisington, Edward J. Van Opstal, Vanessa Varaljay, Nancy Kelley-Loughnane, Camilla A. Mauzy, Michael S. Goodson, Jason W. Soares
Publikováno v:
Environmental Microbiome, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract The Tri-Service Microbiome Consortium (TSMC) was founded to enhance collaboration, coordination, and communication of microbiome research among U.S. Department of Defense (DoD) organizations and to facilitate resource, material and informati
Externí odkaz:
https://doaj.org/article/b9d2551d964a4991ae11c515be181505
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Traveler’s diarrhea (TD) is a recurrent and significant issue for many travelers including the military. While many known enteric pathogens exist that are causative agents of diarrhea, our gut microbiome may also play a role in TD susceptibility. T
Externí odkaz:
https://doaj.org/article/583ec325f5fd46f5a32fd2c57e7cef7c