Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Nancy K. Mello"'
Autor:
F. Ivy Carroll, Bruce E. Blough, Fernando B. de Moura, Stephen J. Kohut, Claire E. Barkin, Nancy K. Mello
Publikováno v:
Exp Clin Psychopharmacol
Chronic health problems associated with long-term nicotine use are the leading cause of preventable death in the United States. The use of tobacco products is 3-4 times greater among individuals with cocaine use disorder than that observed in the gen
Autor:
Nancy K. Mello, Jack H. Mendelson
Publikováno v:
Learning Mechanisms in Smoking ISBN: 9780203787434
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::900f02bf9b258b4ad5e1453496c813bc
https://doi.org/10.4324/9780203787434-19
https://doi.org/10.4324/9780203787434-19
Autor:
Nancy K. Mello, Nathalie V. Goletiani, Michelle B. Sholar, Jack H. Mendelson, Arthur J. Siegel
Publikováno v:
Pharmacology Biochemistry and Behavior. 91:526-536
Nalbuphine, a mixed micro-/kappa-opioid analgesic, may have potential as a new medication for the treatment of cocaine abuse. Kappa-opioid agonists functionally antagonize some abuse-related and locomotor effects of cocaine, and both kappa-selective
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 329:272-281
Monoamine releasers constitute one class of drugs currently under investigation as potential agonist medications for the treatment of cocaine dependence. The efficacy and safety of monoamine releasers as candidate medications may be influenced in par
Autor:
Heather L. Kimmel, Kristin M. Wilcox, John R. Votaw, S. Stevens Negus, Leonard L. Howell, Nancy K. Mello, Jeffrey S. Stehouwer, F. Ivy Carroll, Sarah B. Ewing, Mark M. Goodman
Publikováno v:
Pharmacology Biochemistry and Behavior. 90:453-462
Although inhibition of dopamine transporters (DAT) and the subsequent increase in dopamine clearly play a role in the effects of psychomotor stimulants, the reinforcing effectiveness of DAT inhibitors varies. Previous studies suggest that pharmacokin
Autor:
Arthur J. Siegel, Nathalie V. Goletiani, Michelle B. Sholar, Alicja Skupny, Jack H. Mendelson, Nancy K. Mello
Publikováno v:
Pharmacology Biochemistry and Behavior. 86:667-677
Nalbuphine (Nubain®) is a mixed action mu–kappa agonist used clinically for the management of pain. Nalbuphine and other mu–kappa agonists decreased cocaine self-administration in preclinical models. Cocaine stimulates the hypothalamic–pituita
Publikováno v:
Neuropsychopharmacology. 32:1956-1966
Fluctuations in ovarian steroid hormones across the menstrual/estrous cycle influence the abuse-related effects of acute cocaine administration in women and chronic cocaine self-administration in rodents, but there have been no comparable studies in
Autor:
S. Stevens Negus, Nancy K. Mello
Publikováno v:
Neuropsychopharmacology. 32:1985-1994
The simultaneous i.v. administration of heroin and cocaine, called a 'speedball,' is often reported clinically, and identification of effective pharmacotherapies is a continuing challenge. We hypothesized that treatment with combinations of a monoami
Publikováno v:
Pharmacology Biochemistry and Behavior. 85:744-751
Cocaine stimulates the rapid release of ACTH, and by inference, CRF in several species, suggesting that the HPA “stress” axis may contribute to the abuse-related effects of cocaine. The effects of a systemically-active CRF 1 receptor antagonist,