Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nancy K. Augenstein"'
Publikováno v:
The Journal of Organic Chemistry. 59:7862-7869
Autor:
David O. Calligaro, David Lodge, Paul L. Ornstein, Arnold Macklin Brian, Jack B. Deeter, Darryle D. Schoepp, Nancy K. Augenstein, J. David Leander
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:2067-2072
We report the synthesis and characterization of the enantiomers of some C-6 epimeric tetrazole- and phosphonic acid-substituted decahydroisoquinoline competitive NMDA antagonists. We found that the absolute stereochemistry of the amino acid center wa
Publikováno v:
ChemInform. 22
Autor:
Jack B. Campbell, John D. Millar, Nancy K. Augenstein, D. M. Zimmerman, Macklin Brian Arnold, Paul L. Ornstein, J. W. Chambers, Jonathan W. Paschal, D D Schoepp, David M. Lodge
Publikováno v:
Journal of Medicinal Chemistry. 35:3547-3560
We have prepared a series of 6-substituted decahydroisoquinoline-3-carboxylic acids, and structurally similar analogs, as potential N-methyl-D-aspartate receptor antagonists. There is a large body of evidence to support the use of such compounds as c
Publikováno v:
The Journal of Organic Chemistry. 56:4388-4392
We have prepared three of the four possible diastereomers of ethyl 6-oxo-2-(methoxycarbonyl) decahydroisoquinoline-3-carboxylic acid (two cis- ring and one trans ring juncture ketones, 3a-c) by a convergent route from (±)-m-tyrosine. These ketones a
Autor:
Paul L. Ornstein, D D Schoepp, Macklin Brian Arnold, J. D. Leander, Nancy K. Augenstein, David M. Lodge
Publikováno v:
Journal of medicinal chemistry. 36(14)