Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nancy Jezyk"'
Publikováno v:
Pharmaceutical Research. 16:519-526
Purpose. The purpose of this study was to determine if the intestinal transport of pregabalin (isobutyl -γ-aminobutyric acid, isobutyl GAB A), a new anticonvulsant drug, was mediated by amino acid carriers with affinity for large neutral amino acids
Publikováno v:
Journal of Drug Targeting. 3:15-21
The in vitro permeabilities of 14C labeled dextrans (10, 40, and 70 kD) were calculated from mass transport across Peyer's patches and non-patch tissues derived from rabbit jejunum, and a human colon cell line (Caco-2) grown as a monolayer on polycar
Publikováno v:
Pharmaceutical Research. 10:113-118
The in vitro permeabilities of Caco-2 monolayers and permeabilities in tissue sections from colon of monkey, rabbit, and dog were compared using a series of compounds. The selected compounds differed in their physicochemical properties, such as octan
Publikováno v:
Pharmaceutical Research. :1580-1586
The in vitro permeability of a series of both hydrophilic and lipophilic compounds, as defined by the octanol/water partition coefficient, was measured in four segments of rabbit, monkey, and dog intestine using a side-by-side diffusion cell. A linea