Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Nancy Janzen"'
Autor:
Kevin Wyszatko, Nancy Janzen, Luis Rafael Silva, Luke Kwon, Teesha Komal, Manuela Ventura, Chitra Venugopal, Sheila K. Singh, John F. Valliant, Saman Sadeghi
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background Cancer stem cells play an important role in driving tumor growth and treatment resistance, which makes them a promising therapeutic target to prevent cancer recurrence. Emerging cancer stem cell-targeted therapies would benefit fr
Externí odkaz:
https://doaj.org/article/492baa18e4e34a2ca48ac359ab64cdc4
Autor:
Afaf R. Genady, Samantha R. Slikboer, Rowan Swann, Kevin Wyszatko, Nancy Janzen, Luis Rafael Silva, Mohamed E. El-Zaria, Saman Sadeghi, John F. Valliant
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 4, Iss , Pp 100021- (2022)
Photoacoustic (PA) imaging is a nonradioactive and noninvasive imaging modality that can volumetrically map the distribution of photo-absorbing molecules with deeper tissue penetration than optical modalities. Here, we report on a convenient strategy
Externí odkaz:
https://doaj.org/article/90cffabfae8347119f9b42df3ad7963d
Autor:
Alyssa Vito, Hussain Alarabi, Shannon Czorny, Omid Beiraghi, Jeff Kent, Nancy Janzen, Afaf R Genady, Salma A Al-Karmi, Stephanie Rathmann, Zoya Naperstkow, Megan Blacker, Lisset Llano, Paul J Berti, John F Valliant
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171909 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0167425.].
Externí odkaz:
https://doaj.org/article/6fc4cd242af94f67be03c01544ac5bdf
Autor:
Aimen Zlitni, Melissa Yin, Nancy Janzen, Samit Chatterjee, Ala Lisok, Kathleen L Gabrielson, Sridhar Nimmagadda, Martin G Pomper, F Stuart Foster, John F Valliant
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176958 (2017)
Prostate specific membrane antigen (PSMA) targeted microbubbles (MBs) were developed using bioorthogonal chemistry. Streptavidin-labeled MBs were treated with a biotinylated tetrazine (MBTz) and targeted to PSMA expressing cells using trans-cycloocte
Externí odkaz:
https://doaj.org/article/c3c62eb1ab1045c29b8a08142c1d9cc2
Autor:
Alyssa Vito, Hussain Alarabi, Shannon Czorny, Omid Beiraghi, Jeff Kent, Nancy Janzen, Afaf R Genady, Salma A Al-Karmi, Stephanie Rathmann, Zoya Naperstkow, Megan Blacker, Lisset Llano, Paul J Berti, John F Valliant
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167425 (2016)
A convenient strategy to radiolabel a hydrazinonicotonic acid (HYNIC)-derived tetrazine with 99mTc was developed, and its utility for creating probes to image bone metabolism and bacterial infection using both active and pretargeting strategies was d
Externí odkaz:
https://doaj.org/article/869342b574fd4dd2982219fabc8c7142
Autor:
John F. Valliant, Anthony F. Rullo, Saman Sadeghi, Nancy Janzen, Afaf R. Genady, Stephanie M. Rathmann, Shannon Czorny, Varun C. Anipindi
Publikováno v:
Molecular Pharmaceutics. 18:2647-2656
Building on clinical case reports of the abscopal effect, there has been considerable interest in the synergistic effects of radiation and immunotherapies for the treatment of cancer. Here, the first radiolabeled antibody-recruiting small molecule th
Autor:
Mohamed E. El-Zaria, Mojgan Rezvani, Alex Adronov, Darryl Fong, Afaf R. Genady, Saman Sadeghi, Rowan Swann, John F. Valliant, Stuart A. McNelles, Amber Faraday, Samantha R. Slikboer, Nancy Janzen
Publikováno v:
ACS Applied Nano Materials. 3:11819-11824
Tailoring carbon nanotube surface chemistry is essential for biomedical applications. Bisphosphonate–carbon nanotube conjugates were prepared to target regions of active bone metabolism. The conjug...
Autor:
Christine E. M. Demore, Rowan Swann, Zoya Naperstkow, Johann Le Floc'h, Salma Al-Karmi, Kevin Wyszatko, Yohannes Soenjaya, Stuart Foster, Nancy Janzen, Amber Faraday, John F. Valliant, Samantha R. Slikboer
Publikováno v:
Molecular pharmaceutics. 17(9)
A new photoacoustic (PA) dye was developed as a simple-to-use reagent for creating targeted PA imaging agents. The lead molecule was prepared via an efficient two-step synthesis from an inexpensive commercially available starting material. With the d
Autor:
Vincent Bouvet, Nancy Janzen, John F. Valliant, Melinda Wuest, Frank Wuest, Cody Bergman, Justin J. Bailey
Publikováno v:
Molecular Imaging and Biology. 19:923-932
Prostate-specific membrane antigen (PSMA) is an important biomarker expressed in the majority of prostate cancers. The favorable positron emission tomography (PET) imaging profile of the PSMA imaging agent 2-(3-(1-carboxy-5-[(6-[18F]fluoro-pyridine-3
Autor:
Abdolreza Yazdani, John F. Valliant, Nancy Janzen, Tanya Miladinovic, Shannon Czorny, Robert G. Ungard, Gurmit Singh
Publikováno v:
Dalton Transactions. 46:14691-14699
The aim of this work was to synthesize and evaluate [2 + 1] 99mTc(I) polypyridine complexes containing tetrazines, which along with the corresponding Re(I) complexes, represent a new class of isostructural nuclear and turn-on luminescent probes that