Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nancy J. Linford"'
Re-patterning sleep architecture in Drosophila through gustatory perception and nutritional quality.
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002668 (2012)
Organisms perceive changes in their dietary environment and enact a suite of behavioral and metabolic adaptations that can impact motivational behavior, disease resistance, and longevity. However, the precise nature and mechanism of these dietary res
Externí odkaz:
https://doaj.org/article/50fdc736b2cd4b1992165daae5ae9b28
Publikováno v:
PLoS Biology, Vol 8, Iss 4, p e1000356 (2010)
For nearly all life forms, perceptual systems provide access to a host of environmental cues, including the availability of food and mates as well as the presence of disease and predators. Presumably, individuals use this information to assess the cu
Externí odkaz:
https://doaj.org/article/dcbca9ea4f924387882b73fa79309d53
Publikováno v:
Annual Review of Cell and Developmental Biology. 27:759-785
Sensory systems provide organisms from bacteria to humans with the ability to interact with the world. Numerous senses have evolved that allow animals to detect and decode cues from sources in both their external and internal environments. Recent adv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcffb2ad6091f91556e02da1c2c36b4
https://doi.org/10.1146/annurev-cellbio-092910-154240
https://doi.org/10.1146/annurev-cellbio-092910-154240
Autor:
George M. Martin, Peter S. Rabinovitch, John Morton, Mary J. Emond, Warren C. Ladiges, Sue E. Knoblaugh, Nancy J. Linford, Piper M. Treuting
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 63:813-822
We describe the effects of mitochondrially targeted catalase (MCAT) expression on end-of-life pathology in mice using detailed semiquantitative histopathological evaluation. We previously reported that the median and maximum life spans of MCAT mice w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b2cd5efd342fe703dd0921d6ca1ff5
https://doi.org/10.1093/gerona/63.8.813
https://doi.org/10.1093/gerona/63.8.813
Autor:
Glenna C. Burmer, Nancy J. Linford, Vasiliki Demas, Peter S. Rabinovitch, Richard P. Beyer, Rozlyn A. Krajcik, Virginia L. Malloy, Katherine A. Gollahon
Publikováno v:
Aging Cell. 6:673-688
Sustained caloric restriction (CR) extends lifespan in animal models but the mechanism and primary tissue target(s) have not been identified. Gene expression changes with aging and CR were examined in both heart and white adipose tissue (WAT) of Fisc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae29d56cbcb5852dc6b1125152a3751
https://doi.org/10.1111/j.1474-9726.2007.00319.x
https://doi.org/10.1111/j.1474-9726.2007.00319.x
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(8)
Sleep loss is an adaptive response to nutrient deprivation that alters behavior to maximize the chances of feeding before imminent death. Organisms must maintain systems for detecting the quality of the food source to resume healthy levels of sleep w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec0519ae4cc696a99b92feab1131857
https://pubmed.ncbi.nlm.nih.gov/25675472
https://pubmed.ncbi.nlm.nih.gov/25675472
Autor:
Nancy J. Linford
As we consider the relationship between sleep behavior, human disease, and nutrition, it is interesting to take a step back and ask what one can learn from the other members of the animal kingdom. In terms of comparative biology, it is a bit unfortun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceee5a8606724e11ff33b049ec51161f
https://doi.org/10.1016/b978-0-12-420168-2.00001-6
https://doi.org/10.1016/b978-0-12-420168-2.00001-6
Autor:
Nancy J. Linford, Alexander H. Moskovitz, Richard H. Bell, Peter S. Rabinovitch, Barry E. Storer, Teresa A. Brentnall, John D. Potter, Mary P. Bronner
Publikováno v:
Genes, Chromosomes and Cancer. 37:201-206
Pancreatic adenocarcinoma is a disease with high mortality for which chronic pancreatitis confers a markedly increased risk. We hypothesize that chromosome instability and genomic damage occur in pre-neoplastic pancreatic ductal epithelium, and that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4c4fc6496c809237e2008e5a59cc09
https://doi.org/10.1002/gcc.10189
https://doi.org/10.1002/gcc.10189
Publikováno v:
Journal of Neurocytology. 29:367-374
A review of the literature reveals an impressively broad spectrum of effects of the hormone estrogen in the CNS. One of the more recently documented is the ability of estrogen to protect neurons from cell death associated with a variety of insults. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdce61c60e91944aaea38840f78f2955
https://doi.org/10.1023/a:1007113323582
https://doi.org/10.1023/a:1007113323582
Publikováno v:
Proceedings of the National Academy of Sciences. 95:13947-13952
The voltage-gated sodium channel is the site of action of more than six classes of neurotoxins and drugs that alter its function by interaction with distinct, allosterically coupled receptor sites. Batrachotoxin (BTX) is a steroidal alkaloid that bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd36bfbd02c0afa6a911c6e90789186e
https://doi.org/10.1073/pnas.95.23.13947
https://doi.org/10.1073/pnas.95.23.13947