Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Nancy J Wandersee"'
Autor:
Jonathan R Lindner, Todd Belcik, Michael Widlansky, Leanne M Harmann, Matthew S Karafin, Nancy J Wandersee, Maneka Puligandla, Donna Neuberg, Joel Linden, Joshua J Field
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218783 (2019)
In patients with sickle cell disease (SCD), poor outcome measures compromise the potential success of clinical trials. Contrast-enhanced ultrasound (CEUS) is a technique that can non-invasively quantify deep tissue microvascular blood flow. We tested
Externí odkaz:
https://doaj.org/article/8234e52dd95d4e378069350cb83bfcde
Autor:
Matthew S Karafin, Guangyu Chen, Nancy J Wandersee, Amanda M Brandow, Robert W Hurley, Pippa Simpson, Doug Ward, Shi-Jiang Li, Joshua J Field
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216994 (2019)
Chronic pain affects 50% of adults with sickle cell disease (SCD). Although central sensitization is thought to contribute to the pathogenesis of this chronic pain, no studies have examined differences in functional connectivity of the brain between
Externí odkaz:
https://doaj.org/article/0d8fb1279f8244e993baeff2631b55f0
Autor:
Borna Mehrad, Marie D. Burdick, Nancy J. Wandersee, Kaushik S. Shahir, Liyun Zhang, Pippa M. Simpson, Robert M. Strieter, Joshua J. Field
Publikováno v:
Blood Advances, Vol 1, Iss 24, Pp 2217-2224 (2017)
Abstract: Lung injury and fibrosis are common in patients with sickle cell disease (SCD). Fibrocytes, a population of circulating, bone marrow–derived cells, have been linked to development and progression of tissue fibrogenesis and have been impli
Externí odkaz:
https://doaj.org/article/b57fbf4423ce4aa4b698775bba895871
Autor:
Jawad Hussain, Thomas W. Heinrich, Liyun Zhang, Matthew S. Karafin, Pippa Simpson, Nancy J. Wandersee, Robert W. Hurley, Joshua J. Field, Arun K Singavi
Publikováno v:
Hematology. 23:856-863
In adults with sickle cell disease (SCD), pain often necessitates opioid use. Few studies have examined the relationship between opioid use and health-related quality of life (HRQOL) in adults with SCD. We tested the hypothesis that higher doses of o
Autor:
Robert M. Strieter, Liyun Zhang, Marie D. Burdick, Borna Mehrad, Kaushik Shahir, Pippa Simpson, Joshua J. Field, Nancy J. Wandersee
Publikováno v:
Blood Advances. 1:2217-2224
Lung injury and fibrosis are common in patients with sickle cell disease (SCD). Fibrocytes, a population of circulating, bone marrow-derived cells, have been linked to development and progression of tissue fibrogenesis and have been implicated in the
Autor:
Cheryl A. Hillery, Cheryl L. Stucky, Yihe Guo, Katherine J. Zappia, Dawn Retherford, Nancy J. Wandersee
Publikováno v:
British Journal of Haematology. 179:657-666
Sickle cell trait (SCT) has classically been categorized as a benign condition except in rare cases or upon exposure to severe physical conditions. However, several lines of evidence indicate that individuals with SCT are not always asymptomatic, and
Autor:
Pippa Simpson, Shi-Jiang Li, Matthew S. Karafin, Joshua J. Field, Guangyu Chen, Nancy J. Wandersee, Amanda M. Brandow, Robert W. Hurley, Doug Ward
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216994 (2019)
PLoS ONE, Vol 14, Iss 5, p e0216994 (2019)
Chronic pain affects 50% of adults with sickle cell disease (SCD). Although central sensitization is thought to contribute to the pathogenesis of this chronic pain, no studies have examined differences in functional connectivity of the brain between
Autor:
Julie A. Panepinto, Cheryl L. Stucky, Raymond G. Hoffmann, Mahua Dasgupta, Cheryl A. Hillery, Amanda M. Brandow, Nancy J. Wandersee
Publikováno v:
British journal of haematology. 175(2)
Summary Sickle cell disease (SCD) pain transitions from acute to chronic for unknown reasons. Chronic elevation of the pain neurotransmitter substance P (SP) sensitizes pain nociceptors. We evaluated SP levels in controls and SCD patients during base
Autor:
Cheryl A. Hillery, Cheryl L. Stucky, Daniel Vilceanu, Patrick C. Kerstein, Dawn Retherford, Nancy J. Wandersee, Marie E. Barabas, Amanda M. Brandow
Publikováno v:
Blood. 118:3376-3383
Pain is the leading cause of emergency department visits, hospitalizations, and daily suffering in individuals with sickle cell disease (SCD). The pathologic mechanisms leading to the perception of pain during acute RBC sickling episodes and developm
Publikováno v:
British Journal of Haematology. 144:434-445
Ca2+-calmodulin (Ca2+-CaM) activates erythrocyte adenosine monophosphate deaminase (AMPD) in conditions of disturbed calcium homeostasis, prompting us to investigate adenine nucleotide metabolic dysregulation in sickle cell disease (SCD). However, hi