Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Nancy J Hong"'
Autor:
Autumn Brostek, Nancy J. Hong, Ronghao Zhang, Beau R. Forester, Lauren E. Barmore, Lindsey Kaydo, Nicholas Kluge, Corey Smith, Jeffrey L. Garvin, Agustin Gonzalez‐Vicente
Publikováno v:
Physiological Reports, Vol 10, Iss 19, Pp n/a-n/a (2022)
Abstract Proximal tubule fructose metabolism is key to fructose‐induced hypertension, but the roles of sex and stress are unclear. We hypothesized that females are resistant to the salt‐sensitive hypertension caused by low amounts of dietary fruc
Externí odkaz:
https://doaj.org/article/ce6b04dce8884acba616e8aa7eef342c
Autor:
Autumn Brostek, Nancy J Hong, Ronghao Zhang, Lindsey Kaydo, Nicholas Kluge, Corey Smith, Jeffrey Garvin, Agustin Gonzalez-Vicente
Publikováno v:
Hypertension. 79
Proximal tubule fructose metabolism is key to fructose-induced hypertension, but the roles of sex and stress are unclear. We hypothesized that females are resistant to the salt-sensitive hypertension caused by low amounts of dietary fructose compared
Publikováno v:
Am J Physiol Renal Physiol
Angiotensin II (ANG II) stimulates proximal nephron transport via activation of classical protein kinase C (PKC) isoforms. Acute fructose treatment stimulates PKC and dietary fructose enhances ANG II’s ability to stimulate Na+transport, but the mec
Autor:
Agustin Gonzalez-Vicente, Nancy J. Hong, Nianxin Yang, Pablo D. Cabral, Jessica M. Berthiaume, Fernando P. Dominici, Jeffrey L. Garvin
Publikováno v:
Nutrients, Vol 10, Iss 9, p 1244 (2018)
Dietary fructose causes salt-sensitive hypertension. Proximal tubules (PTs) reabsorb 70% of the filtered NaCl. Angiotensin II (Ang II), atrial natriuretic peptide (ANP) and norepinephrine (NE) regulate this process. Although Ang II signaling blockade
Externí odkaz:
https://doaj.org/article/f1d29b66469a47088337c5dbbe3c386f
Publikováno v:
Am J Physiol Renal Physiol
Dahl salt-sensitive (SS) rat kidneys produce less nitric oxide (NO) than those of salt-resistant (SR) rats. Thick ascending limb (TAL) NO synthase 3 (NOS3) is a major source of renal NO, and luminal flow enhances its activity. We hypothesized that fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049c02e78976939540bfce89b98a5ecf
https://europepmc.org/articles/PMC8530749/
https://europepmc.org/articles/PMC8530749/
Autor:
Jessica Asirwatham, Nancy J. Hong, Fara Saez, Jeffrey L. Garvin, Pablo D. Cabral, Agustin Gonzalez-Vicente
Publikováno v:
American Journal of Physiology-Renal Physiology. 316:F473-F480
Fructose consumption has increased because of widespread use of high-fructose corn syrup by the food industry. Renal proximal tubules are thought to reabsorb fructose. However, fructose reabsorption (Jfructose) by proximal tubules has not yet been di
Autor:
Agustin Gonzalez-Vicente, Pablo D. Cabral, Nancy J. Hong, Jessica Asirwatham, Nianxin Yang, Jessica M. Berthiaume, Fernando P. Dominici, Jeffrey L. Garvin
Publikováno v:
Nutrients, Vol 9, Iss 8, p 885 (2017)
Fructose-enriched diets cause salt-sensitive hypertension. Proximal tubules (PTs) reabsorb 70% of the water and salt filtered through the glomerulus. Angiotensin II (Ang II) regulates this process. Normally, dietary salt reduces Ang II allowing the k
Externí odkaz:
https://doaj.org/article/50c5dc2f7c6a47bbb666c7fb2b4d6016
Publikováno v:
Hypertension
Mechanical stretch raises intracellular Ca (Ca(i)) in many cell types. Luminal flow-derived stretch stimulates O(2)(−) production by thick ascending limbs (THALs). Renal O(2)(−) is greater in Dahl salt-sensitive (SS) than salt-resistant (SR) rats
Publikováno v:
Hypertension. 74
Dietary fructose causes salt-sensitive hypertension. This is in part due to increasing the sensitivity of proximal nephron Na reabsorption to angiotensin II (Ang II) such that lower concentrations stimulate transport to a greater extent. Ang II stimu
Publikováno v:
Am J Physiol Renal Physiol
Reactive oxygen species (ROS) play a critical role in regulating nephron transport both via transcellular and paracellular pathways under physiological and pathological circumstances. Here, we review the progress made in the past ~10 yr in understand