Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Nancy J, Rusch"'
Autor:
Rami A. Shahror, Esraa Shosha, Carol Morris, Melissa Wild, Shengyu Mu, Gabor Csanyi, Marjan Boerma, Nancy J. Rusch, Abdelrahman Y. Fouda
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Ischemia-induced retinopathy is a hallmark finding of common visual disorders including diabetic retinopathy (DR) and central retinal artery and vein occlusions. Treatments for ischemic retinopathies fail to improve clinical outcomes and the
Externí odkaz:
https://doaj.org/article/2e407af8ac314c83a3be54573247bc0d
Autor:
Yuet‐Kin Leung, Sung‐Gwon Lee, Jiang Wang, Ponmari Guruvaiah, Nancy J Rusch, Shuk‐Mei Ho, Chungoo Park, Kyounghyun Kim
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract The orphan nuclear receptor NR2E3 (Nuclear receptor subfamily 2 group E, Member 3) is an epigenetic player that modulates chromatin accessibility to activate p53 during liver injury. Nonetheless, a precise tumor suppressive and epigenetic ro
Externí odkaz:
https://doaj.org/article/615de532653f4dd2b82fcc5a847c2d85
Autor:
Rami A. Shahror, Carol A. Morris, Aya A. Mohammed, Melissa Wild, Bushra Zaman, Christian D. Mitchell, Paul H. Phillips, Nancy J. Rusch, Esraa Shosha, Abdelrahman Y. Fouda
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Myeloid cells including microglia and macrophages play crucial roles in retinal homeostasis by clearing cellular debris and regulating inflammation. These cells are activated in several blinding ischemic retinal diseases including diabetic r
Externí odkaz:
https://doaj.org/article/685e6e4a04e44f4d9e6e13c86e8b8049
Autor:
Esraa Shosha, Rami A. Shahror, Carol A. Morris, Zhimin Xu, Rudolf Lucas, Meghan E. McGee-Lawrence, Nancy J. Rusch, Ruth B. Caldwell, Abdelrahman Y. Fouda
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-14 (2023)
Abstract The enzyme arginase 1 (A1) hydrolyzes the amino acid arginine to form L-ornithine and urea. Ornithine is further converted to polyamines by the ornithine decarboxylase (ODC) enzyme. We previously reported that deletion of myeloid A1 in mice
Externí odkaz:
https://doaj.org/article/86d72afde3964ebdb05e33acaea7cc03
Autor:
Amanda J. Stolarz, Shengyu Mu, Huiliang Zhang, Abdelrahman Y. Fouda, Nancy J. Rusch, Zufeng Ding
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/816573a6c8fa42bf9286571479b322ff
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The lymphatic circulation is an important component of the circulatory system in humans, playing a critical role in the transport of lymph fluid containing proteins, white blood cells, and lipids from the interstitial space to the central venous circ
Externí odkaz:
https://doaj.org/article/561f3b66f3414eed9739ca3656497468
Autor:
Serena Van, Soumiya Pal, Brittney R. Garner, Kate Steed, Vijayalakshmi Sridharan, Shengyu Mu, Nancy J. Rusch, Amanda J. Stolarz
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background and Purpose: Doxorubicin (DOX) is a risk factor for arm lymphedema in breast cancer patients. We reported that DOX opens ryanodine receptors (RYRs) to enact “calcium leak,” which disrupts the rhythmic contractions of lymph vessels (LVs
Externí odkaz:
https://doaj.org/article/aa9d2c03b2be4991b7f10452c5d54aac
Autor:
Shijie Liu, Jinzi Wu, Amanda Stolarz, Huiliang Zhang, Marjan Boerma, Stephanie D. Byrum, Nancy J Rusch, Zufeng Ding
Publikováno v:
Theranostics. 13:2914-2929
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::969fcbddd7b46eb4d5a0d292c7935881
https://doi.org/10.7150/thno.83914
https://doi.org/10.7150/thno.83914
Autor:
Xingyun Qi, Nancy J. Rusch, Jiaojiao Fan, Christoph J. Mora, Lixin Xie, Shengyu Mu, Peter S. Rabinovitch, Huiliang Zhang
Publikováno v:
GeroScience.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47a35ec29aeb5a3161c9b5b2dea5765b
https://doi.org/10.1007/s11357-023-00757-x
https://doi.org/10.1007/s11357-023-00757-x
Autor:
Nancy J. Rusch, Daniel Stuckey, Amanda J. Stolarz, Shengyu Mu, Mustafa Sarimollaoglu, Brittney R. Garner, Philip Palade, Yunmeng Liu
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 376:40-50
Pharmacological openers of ATP-sensitive potassium (KATP) channels are effective antihypertensive agents, but off-target effects, including severe peripheral edema, limit their clinical usefulness. It is presumed that the arterial dilation induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5be050d96270c738d6c06f357dfdc795
https://doi.org/10.1124/jpet.120.000121
https://doi.org/10.1124/jpet.120.000121