Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nancy J, Francoeur"'
Autor:
Denis Torre, Nancy J. Francoeur, Yael Kalma, Ilana Gross Carmel, Betsaida S. Melo, Gintaras Deikus, Kimaada Allette, Ron Flohr, Maya Fridrikh, Konstantinos Vlachos, Kent Madrid, Hardik Shah, Ying-Chih Wang, Shwetha H. Sridhar, Melissa L. Smith, Efrat Eliyahu, Foad Azem, Hadar Amir, Yoav Mayshar, Ivan Marazzi, Ernesto Guccione, Eric Schadt, Dalit Ben-Yosef, Robert Sebra
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Human preimplantation development involves extensive remodeling of RNA expression and splicing. However, its transcriptome has been compiled using short-read sequencing data, which fails to capture most full-length mRNAs. Here, we generate a
Externí odkaz:
https://doaj.org/article/c3c20aad7f8e43afbec8ac8c0333cada
Autor:
Noam D. Beckmann, Phillip H. Comella, Esther Cheng, Lauren Lepow, Aviva G. Beckmann, Scott R. Tyler, Konstantinos Mouskas, Nicole W. Simons, Gabriel E. Hoffman, Nancy J. Francoeur, Diane Marie Del Valle, Gurpawan Kang, Anh Do, Emily Moya, Lillian Wilkins, Jessica Le Berichel, Christie Chang, Robert Marvin, Sharlene Calorossi, Alona Lansky, Laura Walker, Nancy Yi, Alex Yu, Jonathan Chung, Matthew Hartnett, Melody Eaton, Sandra Hatem, Hajra Jamal, Alara Akyatan, Alexandra Tabachnikova, Lora E. Liharska, Liam Cotter, Brian Fennessy, Akhil Vaid, Guillermo Barturen, Hardik Shah, Ying-chih Wang, Shwetha Hara Sridhar, Juan Soto, Swaroop Bose, Kent Madrid, Ethan Ellis, Elyze Merzier, Konstantinos Vlachos, Nataly Fishman, Manying Tin, Melissa Smith, Hui Xie, Manishkumar Patel, Kai Nie, Kimberly Argueta, Jocelyn Harris, Neha Karekar, Craig Batchelor, Jose Lacunza, Mahlet Yishak, Kevin Tuballes, Ieisha Scott, Arvind Kumar, Suraj Jaladanki, Charuta Agashe, Ryan Thompson, Evan Clark, Bojan Losic, Lauren Peters, The Mount Sinai COVID-19 Biobank Team, Panagiotis Roussos, Jun Zhu, Wenhui Wang, Andrew Kasarskis, Benjamin S. Glicksberg, Girish Nadkarni, Dusan Bogunovic, Cordelia Elaiho, Sandeep Gangadharan, George Ofori-Amanfo, Kasey Alesso-Carra, Kenan Onel, Karen M. Wilson, Carmen Argmann, Supinda Bunyavanich, Marta E. Alarcón-Riquelme, Thomas U. Marron, Adeeb Rahman, Seunghee Kim-Schulze, Sacha Gnjatic, Bruce D. Gelb, Miriam Merad, Robert Sebra, Eric E. Schadt, Alexander W. Charney
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Multisystem inflammatory syndrome in children (MIS-C) onsets in COVID-19 patients with manifestations similar to Kawasaki disease (KD). Here the author probe the peripheral blood transcriptome of MIS-C patients to find signatures related to natural k
Externí odkaz:
https://doaj.org/article/7233a40d610f443eac2e6011b12c9368
Autor:
Molly Estill, Efrain Ribeiro, Nancy J. Francoeur, Melissa L. Smith, Robert Sebra, Szu-Ying Yeh, Ashley M. Cunningham, Eric J. Nestler, Li Shen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract To better understand the full-length transcriptome of the nucleus accumbens (NAc)—a key brain reward region—in chronic cocaine treatment, we perform the first single molecule, long-read sequencing analysis using the Iso-seq method to det
Externí odkaz:
https://doaj.org/article/63fe549b0c524dd38ff824a5f1b22884
Autor:
Kira L. Tomlinson, Tania Wong Fok Lung, Felix Dach, Medini K. Annavajhala, Stanislaw J. Gabryszewski, Ryan A. Groves, Marija Drikic, Nancy J. Francoeur, Shwetha H. Sridhar, Melissa L. Smith, Sara Khanal, Clemente J. Britto, Robert Sebra, Ian Lewis, Anne-Catrin Uhlemann, Barbara C. Kahl, Alice S. Prince, Sebastián A. Riquelme
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The authors show that the pathogen Staphylococcus aureus induces a distinct airway immunometabolic response, dominated by release of itaconate. This metabolite, in turn, potentiates extracellular polysaccharide synthesis and biofilm formation in S. a
Externí odkaz:
https://doaj.org/article/31b0833e7deb4acab5af4327ac64931d
Autor:
Leonard Schärfen, Dagmar Zigackova, Kirsten A. Reimer, Martha R. Stark, Viktor A. Slat, Nancy J. Francoeur, Melissa L. Wells, Lecong Zhou, Perry J. Blackshear, Karla M. Neugebauer, Stephen D. Rader
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Alternative polyadenylation (APA) is widespread among metazoans and has been shown to have important impacts on mRNA stability and protein expression. Beyond a handful of well-studied organisms, however, its existence and consequences have not been w
Externí odkaz:
https://doaj.org/article/102645cef62646d1ae3cbf4698f7fb79
Autor:
Arpit Dave, Daniel Charytonowicz, Nancy J. Francoeur, Michael Beaumont, Kristin Beaumont, Hank Schmidt, Tizita Zeleke, Jose Silva, Robert Sebra
Publikováno v:
Cellular oncology (Dordrecht).
Purpose Breast Cancer (BC) is the most diagnosed cancer in women; however, through significant research, relative survival rates have significantly improved. Despite progress, there remains a gap in our understanding of BC subtypes and personalized t
Autor:
Marion Déjosez, Arturo Marin, Graham M. Hughes, Ariadna E. Morales, Carlos Godoy-Parejo, Jonathan Gray, Yiren Qin, Arun A. Singh, Hui Xu, Javier Juste, Carlos Ibáñez, Kris M. White, Romel Rosales, Nancy J. Francoeur, Robert P. Sebra, Dominic Alcock, Sébastien J. Puechmaille, Andrzej Pastusiak, Simon D.W. Frost, Michael Hiller, Richard A. Young, Emma C. Teeling, Adolfo García-Sastre, Thomas P. Zwaka
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Bats have evolved features unique amongst mammals, including flight, laryngeal echolocation, and certain species have been shown to have a unique immune response that may enable them to tolerate viruses such as SARS-CoVs, MERS-CoVs, Nipah, and Marbur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5ff677d6d0a24a155cfd059e23f6a6c
https://doi.org/10.1101/2022.09.23.509261
https://doi.org/10.1101/2022.09.23.509261
Autor:
Marion Déjosez, Arturo Marin, Graham M. Hughes, Ariadna E. Morales, Carlos Godoy-Parejo, Jonathan L. Gray, Yiren Qin, Arun A. Singh, Hui Xu, Javier Juste, Carlos Ibáñez, Kris M. White, Romel Rosales, Nancy J. Francoeur, Robert P. Sebra, Dominic Alcock, Thomas L. Volkert, Sébastien J. Puechmaille, Andrzej Pastusiak, Simon D.W. Frost, Michael Hiller, Richard A. Young, Emma C. Teeling, Adolfo García-Sastre, Thomas P. Zwaka
Publikováno v:
Cell. 186:957-974.e28
Autor:
Leonard, Schärfen, Dagmar, Zigackova, Kirsten A, Reimer, Martha R, Stark, Viktor A, Slat, Nancy J, Francoeur, Melissa L, Wells, Lecong, Zhou, Perry J, Blackshear, Karla M, Neugebauer, Stephen D, Rader
Publikováno v:
Frontiers in genetics. 12
Alternative polyadenylation (APA) is widespread among metazoans and has been shown to have important impacts on mRNA stability and protein expression. Beyond a handful of well-studied organisms, however, its existence and consequences have not been w
Autor:
Ryan C, Thompson, Nicole W, Simons, Lillian, Wilkins, Esther, Cheng, Diane Marie, Del Valle, Gabriel E, Hoffman, Carlo, Cervia, Brian, Fennessy, Konstantinos, Mouskas, Nancy J, Francoeur, Jessica S, Johnson, Lauren, Lepow, Jessica, Le Berichel, Christie, Chang, Aviva G, Beckmann, Ying-Chih, Wang, Kai, Nie, Nicholas, Zaki, Kevin, Tuballes, Vanessa, Barcessat, Mario A, Cedillo, Dan, Yuan, Laura, Huckins, Panos, Roussos, Thomas U, Marron, Benjamin S, Glicksberg, Girish, Nadkarni, James R, Heath, Edgar, Gonzalez-Kozlova, Onur, Boyman, Seunghee, Kim-Schulze, Robert, Sebra, Miriam, Merad, Sacha, Gnjatic, Eric E, Schadt, Alexander W, Charney, Renyuan, Zha
Publikováno v:
Nature medicine.
Post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are debilitating, clinically heterogeneous and of unknown molecular etiology. A transcriptome-wide investigation was performed in 165 acutely infected hospi