Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nancy Hurtado-Ziola"'
Autor:
Sandra L Diaz, Vered Padler-Karavani, Darius Ghaderi, Nancy Hurtado-Ziola, Hai Yu, Xi Chen, Els C M Brinkman-Van der Linden, Ajit Varki, Nissi M Varki
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4241 (2009)
Humans are genetically defective in synthesizing the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc), but can metabolically incorporate it from dietary sources (particularly red meat and milk) into glycoproteins and glycolipids of hum
Externí odkaz:
https://doaj.org/article/334e1e034bbb495c9bc521e341aed29a
Autor:
Richard Schwab, Ajit Varki, Xi Chen, Karen Messer, Yu-Tsueng Liu, Inder M. Verma, Darius Ghaderi, Oded Singer, Dinorah Friedmann-Morvinski, Patrick Secrest, Hongzhi Cao, Harshal A. Chokhawala, Saddam Muthana, Shengshu Huang, Hai Yu, Minya Pu, Nancy Hurtado-Ziola, Vered Padler-Karavani
Supplementary Figures 1-4, Tables 1-2 from Human Xeno-Autoantibodies against a Non-Human Sialic Acid Serve as Novel Serum Biomarkers and Immunotherapeutics in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3e4ac08ea8fef06a087815915a6137
https://doi.org/10.1158/0008-5472.22392473
https://doi.org/10.1158/0008-5472.22392473
Publikováno v:
Biotechnology and Genetic Engineering Reviews. 28:147-176
One of the fastest growing fields in the pharmaceutical industry is the market for therapeutic glycoproteins. Today, these molecules play a major role in the treatment of various diseases, and include several protein classes, i.e., clotting factors,
Publikováno v:
Blood. 114:3668-3676
ABH(O) blood group polymorphisms are based on well-known intraspecies variations in structures of neutral blood cell surface glycans in humans and other primates. Whereas natural antibodies against these glycans can act as barriers to blood transfusi
Autor:
Gunnar Lindahl, Yung-Chi Chang, Ajit Varki, Thomas Areschoug, Victor Nizet, Nancy Hurtado-Ziola, Charles C. King, Aaron F. Carlin
Publikováno v:
The Journal of Experimental Medicine
Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation o
Autor:
Nissi Varki, Toshiyuki Hayakawa, Nancy Hurtado-Ziola, Lisa Wiggleton, Kurt Benirschke, Ajit Varki, Els C. M. Brinkman-Van der Linden
Publikováno v:
Glycobiology. 17:922-931
CD33-related-Siglecs are lectins on immune cells that recognize sialic acids via extracellular domains, and deliver negative signals via cytosolic tyrosine-based regulatory motifs. We report that while Siglec-6/OB-BP1 (which can also bind leptin) is
Autor:
Justin L. Sonnenburg, Andrea Verhagen, Yung-Chi Chang, Takashi Angata, Nancy Hurtado-Ziola, Vered Padler-Karavani, Nissi Varki, Ajit Varki, Arash Ronaghy, Xi Chen, Hai Yu, Victor Nizet
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(3)
Siglecs are sialic acid-binding Ig-like lectins that recognize sialoglycans via amino-terminal V-set domains. CD33-related Siglecs (CD33rSiglecs) on innate immune cells recognize endogenous sialoglycans as “self-associated molecular patterns” (SA
Autor:
Harshal A. Chokhawala, Xi Chen, Patrick Secrest, Karen Messer, Saddam Muthana, Vered Padler-Karavani, Oded Singer, Ajit Varki, Dinorah Friedmann-Morvinski, Richard Schwab, Shengshu Huang, Nancy Hurtado-Ziola, Hai Yu, Inder M. Verma, Yu Tsueng Liu, Darius Ghaderi, Hongzhi Cao, Minya Pu
Publikováno v:
Cancer research. 71(9)
Human carcinomas can metabolically incorporate and present the dietary non-human sialic acid Neu5Gc, which differs from the human sialic acid N-acetylneuraminic acid (Neu5Ac) by 1 oxygen atom. Tumor-associated Neu5Gc can interact with low levels of c
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(8)
Although humans and chimpanzees share >99% identity in alignable protein sequences, they differ surprisingly in the incidence and severity of some common diseases. In general, humans infected with various viruses, such as HIV and hepatitis C virus, a
Autor:
Nissi Varki, Xi Chen, Hai Yu, Sandra Diaz, Ajit Varki, Darius Ghaderi, Nancy Hurtado-Ziola, Vered Padler-Karavani, Els C. M. Brinkman-Van der Linden
Publikováno v:
PloS one, vol 4, iss 1
PLoS ONE, Vol 4, Iss 1, p e4241 (2009)
PLoS ONE
PLoS ONE, Vol 4, Iss 1, p e4241 (2009)
PLoS ONE
Background Humans are genetically defective in synthesizing the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc), but can metabolically incorporate it from dietary sources (particularly red meat and milk) into glycoproteins and glycoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de54d38cdc6423a1b277df1562ce0b02
https://escholarship.org/uc/item/9nq6c875
https://escholarship.org/uc/item/9nq6c875