Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Nancy H L Leung"'
Autor:
Jeremy Reich, Mark G Thompson, Benjamin J Cowling, A Danielle Iuliano, Carolyn Greene, Yuyun Chen, Rachael Phadnis, Nancy H L Leung, Ying Song, Vicky J Fang, Cuiling Xu, Qigang Dai, Jun Zhang, Hongjun Zhang, Fiona Havers, CARES investigators
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0234698 (2020)
BackgroundBrief assessments of functional status for community-dwelling older adults are needed given expanded interest in the measurement of functional decline.MethodsAs part of a 2015 prospective cohort study of older adults aged 60-89 years in Jia
Externí odkaz:
https://doaj.org/article/10326eb366914da29ca29680f6a73528
Autor:
Carolyn A. Cohen, Nancy H. L. Leung, Prathanporn Kaewpreedee, Kelly W. K. Lee, Janice Zhirong Jia, Alan W. L. Cheung, Samuel M. S. Cheng, Masashi Mori, Dennis K. M. Ip, Leo L. M. Poon, J. S. Malik Peiris, Benjamin J. Cowling, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Whole virion inactivated vaccine CoronaVac (C) and Spike (S) mRNA BNT162b2 (B) vaccines differ greatly in their ability to elicit neutralizing antibodies but have somewhat comparable effectiveness in protecting from severe COVID-19. We condu
Externí odkaz:
https://doaj.org/article/43c352f9d77447a8b416c96995ea3831
Autor:
Zaolan Liang, Xia Lin, Lihong Sun, Kimberly M. Edwards, Wenjun Song, Hailiang Sun, Yanmin Xie, Fangmei Lin, Shiman Ling, Tingting Liang, Biying Xiao, Jiaqi Wang, Min Li, Chin-Yu Leung, Huachen Zhu, Nisha Bhandari, Raghavan Varadarajan, Min Z. Levine, Malik Peiris, Robert Webster, Vijaykrishna Dhanasekaran, Nancy H. L. Leung, Benjamin J. Cowling, Richard J. Webby, Mariette Ducatez, Mark Zanin, Sook-San Wong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was introduced from avian sources during the 1957 pandemic, we investigate the reacti
Externí odkaz:
https://doaj.org/article/222177c2a96944b098415e28af694ad7
Autor:
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cross-reactive antibodies with Fc receptor (FcR) effector functions may mitigate pandemic virus impact in the absence of neutralizing antibodies. In this exploratory study, we use serum from a randomized placebo-controlled trial of seasonal
Externí odkaz:
https://doaj.org/article/c15b260c86f84dffa03009a6bb0b59de
Autor:
Nancy H L Leung, Jie Zhou, Daniel K W Chu, Han Yu, William G Lindsley, Donald H Beezhold, Hui-Ling Yen, Yuguo Li, Wing-Hong Seto, Joseph S M Peiris, Benjamin J Cowling
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148669 (2016)
The potential for human influenza viruses to spread through fine particle aerosols remains controversial. The objective of our study was to determine whether influenza viruses could be detected in fine particles in hospital rooms.We sampled the air i
Externí odkaz:
https://doaj.org/article/554d5f10d2e1451c907a18ad960a3a37
Autor:
Tim K. Tsang, Kwok-Tai Lam, Yinping Liu, Vicky J. Fang, Xiaofeng Mu, Nancy H. L. Leung, J. S. Malik Peiris, Gabriel M. Leung, Benjamin J. Cowling, Wenwei Tu
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The protective effect of T cell-mediated immunity against influenza virus infections in natural settings remains unclear, especially in seasonal epidemics. Methods To explore the potential of such protection, we analyzed the blood
Externí odkaz:
https://doaj.org/article/ce7914eb109b444984597152877d9f03
Autor:
Benjamin J Cowling, Samuel M S Cheng, Mario Martín-Sánchez, Niki Y M Au, Karl C K Chan, John K C Li, Lison W C Fung, Leo L H Luk, Leo C H Tsang, Dennis K M Ip, Leo L M Poon, Gabriel M Leung, J S Malik Peiris, Nancy H L Leung
Publikováno v:
The Journal of Infectious Diseases. 227:251-255
We administered BNT162b2 as a third dose to 314 adults aged ≥30 years who had previously received 2 doses of inactivated vaccine. We collected blood samples before the third dose and again after 1 month and 6 months, and found robust antibody respo
Autor:
Nancy H L Leung, Samuel M S Cheng, Mario Martín-Sánchez, Niki Y M Au, Yvonne Y Ng, Leo L H Luk, Karl C K Chan, John K C Li, Yonna W Y Leung, Leo C H Tsang, Sara Chaothai, Kelvin K H Kwan, Dennis K M Ip, Leo L M Poon, Gabriel M Leung, J S Malik Peiris, Benjamin J Cowling
Publikováno v:
Clinical Infectious Diseases. 76:e299-e307
Background Limited data exist on antibody responses to mixed vaccination strategies that involve inactivated coronavirus disease 2019 (COVID-19) vaccines, particularly in the context of emerging variants. Methods We conducted an open-label trial of a
Autor:
Janice Zhirong Jia, Chee Wah Tan, Samuel M. S. Cheng, Haogao Gu, Aileen Ying Yan Yeoh, Chris Ka Pun Mok, Yanqun Wang, Jincun Zhao, Nancy H. L. Leung, Benjamin J. Cowling, Leo L. M. Poon, David S. C. Hui, Linfa Wang, Malik Peiris, Sophie A. Valkenburg
Publikováno v:
Nature Communications. 13
Vaccines that are broadly cross-protective against current and future SARS-CoV-2 variants of concern (VoC) or across the sarbecoviruses subgenus remain a priority for public health. Virus neutralization is the best available correlate of protection.
Autor:
Nancy H. L. Leung, Samuel M. S. Cheng, Carolyn A. Cohen, Mario Martín-Sánchez, Niki Y. M. Au, Leo L. H. Luk, Leo C. H. Tsang, Kelvin K. H. Kwan, Sara Chaothai, Lison W. C. Fung, Alan W. L. Cheung, Karl C. K. Chan, John K. C. Li, Yvonne Y. Ng, Prathanporn Kaewpreedee, Janice Z. Jia, Dennis K. M. Ip, Leo L. M. Poon, Gabriel M. Leung, J. S. Malik Peiris, Sophie A. Valkenburg, Benjamin J. Cowling
BackgroundThere are few trials comparing homologous and heterologous third doses of COVID-19 vaccination with inactivated vaccines and mRNA vaccines.MethodsWe conducted an open-label randomized trial in adults >=18 years of age who received two doses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cb3eaba37341c85d2e8e0ba7b3b4fe4
https://doi.org/10.1101/2022.08.25.22279158
https://doi.org/10.1101/2022.08.25.22279158