Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Nancy H L, Leung"'
Autor:
Carolyn A. Cohen, Nancy H. L. Leung, Prathanporn Kaewpreedee, Kelly W. K. Lee, Janice Zhirong Jia, Alan W. L. Cheung, Samuel M. S. Cheng, Masashi Mori, Dennis K. M. Ip, Leo L. M. Poon, J. S. Malik Peiris, Benjamin J. Cowling, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Whole virion inactivated vaccine CoronaVac (C) and Spike (S) mRNA BNT162b2 (B) vaccines differ greatly in their ability to elicit neutralizing antibodies but have somewhat comparable effectiveness in protecting from severe COVID-19. We condu
Externí odkaz:
https://doaj.org/article/43c352f9d77447a8b416c96995ea3831
Autor:
Zaolan Liang, Xia Lin, Lihong Sun, Kimberly M. Edwards, Wenjun Song, Hailiang Sun, Yanmin Xie, Fangmei Lin, Shiman Ling, Tingting Liang, Biying Xiao, Jiaqi Wang, Min Li, Chin-Yu Leung, Huachen Zhu, Nisha Bhandari, Raghavan Varadarajan, Min Z. Levine, Malik Peiris, Robert Webster, Vijaykrishna Dhanasekaran, Nancy H. L. Leung, Benjamin J. Cowling, Richard J. Webby, Mariette Ducatez, Mark Zanin, Sook-San Wong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was introduced from avian sources during the 1957 pandemic, we investigate the reacti
Externí odkaz:
https://doaj.org/article/222177c2a96944b098415e28af694ad7
Autor:
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cross-reactive antibodies with Fc receptor (FcR) effector functions may mitigate pandemic virus impact in the absence of neutralizing antibodies. In this exploratory study, we use serum from a randomized placebo-controlled trial of seasonal
Externí odkaz:
https://doaj.org/article/c15b260c86f84dffa03009a6bb0b59de
Autor:
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/dbcc812df33143d0a5c9724faf5629b8
Autor:
Janice Zhirong Jia, Chee Wah Tan, Samuel M. S. Cheng, Haogao Gu, Aileen Ying Yan Yeoh, Chris Ka Pun Mok, Yanqun Wang, Jincun Zhao, Nancy H. L. Leung, Benjamin J. Cowling, Leo L. M. Poon, David S. C. Hui, Linfa Wang, Malik Peiris, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Vaccination and infection history determine the breadth of neutralizing antibody response to SARS-CoV-2 variants and other sarbecoviruses with breakthrough or natural infection combined with vaccination or booster vaccination with mRNA vaccine provid
Externí odkaz:
https://doaj.org/article/b945fc7acc44408dababd01fdb84c979
Autor:
Tim K. Tsang, Kwok-Tai Lam, Yinping Liu, Vicky J. Fang, Xiaofeng Mu, Nancy H. L. Leung, J. S. Malik Peiris, Gabriel M. Leung, Benjamin J. Cowling, Wenwei Tu
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The protective effect of T cell-mediated immunity against influenza virus infections in natural settings remains unclear, especially in seasonal epidemics. Methods To explore the potential of such protection, we analyzed the blood
Externí odkaz:
https://doaj.org/article/ce7914eb109b444984597152877d9f03
Autor:
Yun Lin, Bingyi Yang, Sarah Cobey, Eric H. Y. Lau, Dillon C. Adam, Jessica Y. Wong, Helen S. Bond, Justin K. Cheung, Faith Ho, Huizhi Gao, Sheikh Taslim Ali, Nancy H. L. Leung, Tim K. Tsang, Peng Wu, Gabriel M. Leung, Benjamin J. Cowling
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
The time-varying effective reproductive number (Rt) is useful for monitoring transmission of infections such as COVID-19, but reporting delays impact case count-based estimation methods. Here, the authors demonstrate and validate a method for estimat
Externí odkaz:
https://doaj.org/article/ad4acc1e524a40de9d1386d6acf90e13
Autor:
Athena P. Y. Li, Carolyn A. Cohen, Nancy H. L. Leung, Vicky J. Fang, Shivaprakash Gangappa, Suryaprakash Sambhara, Min Z. Levine, A. Danielle Iuliano, Ranawaka A. P. M. Perera, Dennis K. M. Ip, J. S. Malik Peiris, Mark G. Thompson, Benjamin J. Cowling, Sophie A. Valkenburg
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract The vaccine efficacy of standard-dose seasonal inactivated influenza vaccines (S-IIV) can be improved by the use of vaccines with higher antigen content or adjuvants. We conducted a randomized controlled trial in older adults to compare cell
Externí odkaz:
https://doaj.org/article/ff75dec103104784802c673035cff753
Autor:
Benjamin J Cowling, Samuel M S Cheng, Mario Martín-Sánchez, Niki Y M Au, Karl C K Chan, John K C Li, Lison W C Fung, Leo L H Luk, Leo C H Tsang, Dennis K M Ip, Leo L M Poon, Gabriel M Leung, J S Malik Peiris, Nancy H L Leung
Publikováno v:
The Journal of Infectious Diseases. 227:251-255
We administered BNT162b2 as a third dose to 314 adults aged ≥30 years who had previously received 2 doses of inactivated vaccine. We collected blood samples before the third dose and again after 1 month and 6 months, and found robust antibody respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96ba5b0046a1e8e490e0bcb869941996
https://doi.org/10.1093/infdis/jiac380
https://doi.org/10.1093/infdis/jiac380
Autor:
Jeremy Reich, Mark G Thompson, Benjamin J Cowling, A Danielle Iuliano, Carolyn Greene, Yuyun Chen, Rachael Phadnis, Nancy H L Leung, Ying Song, Vicky J Fang, Cuiling Xu, Qigang Dai, Jun Zhang, Hongjun Zhang, Fiona Havers, CARES investigators
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0234698 (2020)
BackgroundBrief assessments of functional status for community-dwelling older adults are needed given expanded interest in the measurement of functional decline.MethodsAs part of a 2015 prospective cohort study of older adults aged 60-89 years in Jia
Externí odkaz:
https://doaj.org/article/10326eb366914da29ca29680f6a73528