Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nancy H, Nabilsi"'
Autor:
Mingqi Zhou, Nancy H. Nabilsi, Anqi Wang, Marie-Pierre L. Gauthier, Kevin O. Murray, Hassan Azari, William S. Owens, Jeremy R. B. Newman, Francisco J. Pardo-Palacios, Ana Conesa, Alberto Riva, Thomas L. Clanton, Brent A. Reynolds, Patrick Concannon, Jason O. Brant, Rhonda Bacher, Michael P. Kladde
Targeted sequencing is an increasingly sought technology. Available methods, however, are often costly and yield high proportions of off-target reads. Here, we present FENGC, a scalable, multiplexed method in which target sequences are assembled into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d6118a3c6e2606ff46c3a0b83c3370e
https://doi.org/10.1101/2022.11.08.515732
https://doi.org/10.1101/2022.11.08.515732
Autor:
Florian A. Siebzehnrubl, Daniel J. Silver, Bugra Tugertimur, Loic P. Deleyrolle, Dorit Siebzehnrubl, Matthew R. Sarkisian, Kelly G. Devers, Antony T. Yachnis, Marius D. Kupper, Daniel Neal, Nancy H. Nabilsi, Michael P. Kladde, Oleg Suslov, Simone Brabletz, Thomas Brabletz, Brent A. Reynolds, Dennis A. Steindler
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 8, Pp 1196-1212 (2013)
Abstract Glioblastoma remains one of the most lethal types of cancer, and is the most common brain tumour in adults. In particular, tumour recurrence after surgical resection and radiation invariably occurs regardless of aggressive chemotherapy. Here
Externí odkaz:
https://doaj.org/article/afc2f0c96da4418490133327b9eb231d
Autor:
Tomoki Sunose, Michael P. Kladde, Kazuhiko Igarashi, Suming Huang, Jared R. Stees, Yasushi Kudo, Carolina E. Pardo, Mir A. Hossain, Nancy H. Nabilsi, Jörg Bungert, Russell P. Darst, Rosha Poudyal
Publikováno v:
Molecular and Cellular Biology. 36:238-250
Enhancers and promoters assemble protein complexes that ultimately regulate the recruitment and activity of RNA polymerases. Previous work has shown that at least some enhancers form stable protein complexes, leading to the formation of enhanceosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bcdb388f320eb4da0da4fdfbb76b8e
https://doi.org/10.1128/mcb.00723-15
https://doi.org/10.1128/mcb.00723-15
Autor:
Michael P. Kladde, Brent A. Reynolds, Alberto Riva, Russell P. Darst, Loic P. Deleyrolle, Nancy H. Nabilsi
Publikováno v:
Genome Research. 24:329-339
Human tumors are comprised of heterogeneous cell populations that display diverse molecular and phenotypic features. To examine the extent to which epigenetic differences contribute to intratumoral cellular heterogeneity, we have developed a high-thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9198e96a7db12b16c2988785c08e90
https://doi.org/10.1101/gr.161737.113
https://doi.org/10.1101/gr.161737.113
Autor:
Matthew R. Sarkisian, Brent A. Reynolds, Marius D. Kupper, Kelly G. Devers, Daniel J. Silver, Thomas Brabletz, Bugra Tugertimur, Oleg Suslov, Antony T. Yachnis, Dorit Siebzehnrubl, Simone Brabletz, Michael P. Kladde, Dennis A. Steindler, Daniel Neal, Florian A. Siebzehnrubl, Loic P. Deleyrolle, Nancy H. Nabilsi
Publikováno v:
EMBO Molecular Medicine
Glioblastoma remains one of the most lethal types of cancer, and is the most common brain tumour in adults. In particular, tumour recurrence after surgical resection and radiation invariably occurs regardless of aggressive chemotherapy. Here, we prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc64ea5805249288c50939175295096
http://europepmc.org/articles/PMC3944461
http://europepmc.org/articles/PMC3944461
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1288
Chromatin limits the accessibility of DNA to trans-acting factors in transcription, replication, and repair. Although transcriptional variation between cells in a population may contribute to survival and disease, most assays of chromatin structure r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::924f60a1e57bdac7daf0bb06a3325354
https://pubmed.ncbi.nlm.nih.gov/25827879
https://pubmed.ncbi.nlm.nih.gov/25827879
Publikováno v:
Methods in Molecular Biology ISBN: 9781493924738
Chromatin limits the accessibility of DNA to trans-acting factors in transcription, replication, and repair. Although transcriptional variation between cells in a population may contribute to survival and disease, most assays of chromatin structure r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc4ff7b695449abab6ec190e965fc1aa
https://doi.org/10.1007/978-1-4939-2474-5_9
https://doi.org/10.1007/978-1-4939-2474-5_9
Autor:
Jennifer Pavlica, Drew Cheney, Leendert Cloete, Nancy H. Nabilsi, Rachel Kasinskas, Ida van Jaarsveld
Publikováno v:
Cancer Research. 77:5411-5411
High resolution RNA analysis using next-generation sequencing (RNA-seq) is a rapidly growing application in cancer research. Formalin-fixed paraffin-embedded (FFPE) tissue is a ubiquitous resource for clinical studies. However, the ability to generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05fa8d2ec96b03f4260da0bb8c9b81ba
https://doi.org/10.1158/1538-7445.am2017-5411
https://doi.org/10.1158/1538-7445.am2017-5411
Autor:
Nancy H. Nabilsi, Jaimin S. Patel, Dennis A. Steindler, Loic P. Deleyrolle, Mark Rohaus, Nick Pasternack, Benjamin Griffith, Brent A. Reynolds, Florian A. Siebzehnrubl, Angus Harding, Kyle Dajac, Michael P. Kladde
Glioblastoma, the most frequent primary malignancy of the central nervous system, is almost universally fatal despite aggressive therapies, such as surgical resection, adjuvant radiation and chemotherapy, which remain largely palliative. With increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d4afd00100876484e8b2bfd90573ed
https://europepmc.org/articles/PMC4217961/
https://europepmc.org/articles/PMC4217961/
Autor:
Daniel J. Ryder, David S. Loose, Ashley C. Peraza-Penton, Rosha Poudyal, Michael P. Kladde, Nancy H. Nabilsi
Genome-scale mapping suggests that the function of DNA methylation varies with genomic context beyond transcriptional repression. However, the use of DNA-demethylating agents (e.g. 5-aza-2'-deoxycytidine (5aza-dC)) to study epigenetic regulation ofte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b766de2ac2f4fc6ad86d87b47fb0a3a2
https://europepmc.org/articles/PMC3861643/
https://europepmc.org/articles/PMC3861643/