Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nancy Goebl"'
Autor:
Victor W. Pike, Nancy Goebl, Talakad G. Lohith, Maria Ferraris Araneta, Vanessa N. Barth, Cheryl L. Morse, Johannes Tauscher, Sami S. Zoghbi, Robert B. Innis, Masahiro Fujita
Publikováno v:
Journal of Nuclear Medicine. 53:385-392
Nociceptin/orphanin FQ peptide (NOP) receptor is a new class of opioid receptor that may play a pathophysiologic role in anxiety and drug abuse and is a potential therapeutic target in these disorders. We previously developed a high-affinity PET liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b30bc1e740836c12f6cacd569901d5
https://doi.org/10.2967/jnumed.111.097162
https://doi.org/10.2967/jnumed.111.097162
Publikováno v:
Toxicologic Pathology. 35:541-548
A sensitive method has been developed for the identification and assessment of phosphorothioate oligonucleotide accumulation in dosed animal tissues using an in situ hybridization approach, which is both sequence specific yet adaptable to every antis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d9ec461a7c6e727cdb78beb6385d88
https://doi.org/10.1080/01926230701338958
https://doi.org/10.1080/01926230701338958
Autor:
Nancy Goebl, Maria Ferraris Araneta, Masahiro Fujita, Johannes Tauscher, Victor W. Pike, Sami S. Zoghbi, Vanessa N. Barth, Cheryl L. Morse, Talakad G. Lohith, Robert B. Innis
Publikováno v:
NeuroImage. 87
[11C]NOP-1A is a novel high-affinity PET ligand for imaging nociceptin/orphanin FQ peptide (NOP) receptors. Here, we report reproducibility and reliability measures of binding parameter estimates for [11C]NOP-1A binding in the brain of healthy humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00144774de6bc10288c632af847f6794
https://pubmed.ncbi.nlm.nih.gov/24225488
https://pubmed.ncbi.nlm.nih.gov/24225488
Autor:
John Joseph Masters, Robert B. Innis, Johannes Tauscher, Victor W. Pike, Paolo Zanotti-Fregonara, David T. Clark, Bruce A. Dressman, Emily Rhoads, Debra Luffer-Atlas, Sami S. Zoghbi, Vanessa N. Barth, Nancy Goebl, Beverly A. Heinz, Cheryl L. Morse, Kuklish Steven Lee, Elizabeth M. Joshi, Edward R. Siuda, Jeih San Liow, Matthew J. Fisher, Eric S. Nisenbaum
Two allosteric modulators of the group I metabotropic glutamate receptors (mGluR1 and mGluR5) were evaluated as positron emission tomography (PET) radioligands for mGluR1.LY2428703, a full mGluR1 antagonist (IC(50) 8.9 nM) and partial mGluR5 antagoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c40593c3a7a8e5e4ee3b7ed79ddb0a
https://europepmc.org/articles/PMC3537910/
https://europepmc.org/articles/PMC3537910/
Autor:
Kenneth W. Dunn, Nancy Goebl, Clifford M. Babbey, Derrick R. Witcher, Victor J. Wroblewski, Amita Datta-Mannan
Publikováno v:
Molecular biology of the cell. 19(12)
The neonatal Fc receptor, FcRn mediates an endocytic salvage pathway that prevents degradation of IgG, thus contributing to the homeostasis of circulating IgG. Based on the low affinity of IgG for FcRn at neutral pH, internalization of IgG by endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c47674c20638c650cdcfd279ed09bc
https://pubmed.ncbi.nlm.nih.gov/18843053
https://pubmed.ncbi.nlm.nih.gov/18843053
Autor:
Nancy Goebl, Johannes Tauscher, Shannan Henry, Alexander Neumeister, Henry Huang, Ming Zheng, Beata Planeta-Wilson, Giampaolo Tomasi, Shu-fei Lin, Richard E. Carson
Publikováno v:
NeuroImage. 52:S39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f0c4422e26c355c0f6438d5cc68c0e6
https://doi.org/10.1016/j.neuroimage.2010.04.221
https://doi.org/10.1016/j.neuroimage.2010.04.221