Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Nancy Gavert"'
Autor:
Shay Golan, Vered Bar, Seth J. Salpeter, Guy Neev, German Creiderman, Daniel Kedar, Sara Aharon, Lubov Turovsky, Adi Zundelevich, Hamutal Shahar, Hagit Shapira, Giuseppe Mallel, Erez Stossel, Nancy Gavert, Ravid Straussman, Zohar Dotan, Raanan Berger, Chani Stossel, Talia Golan, Sharon Halperin, Dan Leibovici, Shani Breuer, Yakir Rottenberg, Liat Applebaum, Ayala Hubert, Hovav Nechushtan, Tamar Peretz, Aviad Zick, Boris Chertin, Dmitry Koulikov, Amir Sonnenblick, Eli Rosenbaum
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionEx vivo organ cultures (EVOC) were recently optimized to sustain cancer tissue for 5 days with its complete microenvironment. We examined the ability of an EVOC platform to predict patient response to cancer therapy.MethodsA multicenter,
Externí odkaz:
https://doaj.org/article/9e606d0806d6437093649828fdd409d0
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13418 (2023)
An induction in the expression of the cell adhesion receptor L1, a Wnt target gene, is a characteristic feature of Wnt/β-catenin activation in colon cancer cells at later stages of the disease. We investigated the proteins secreted following L1 expr
Externí odkaz:
https://doaj.org/article/0c1d3c28290b4dcaa771884f61c65882
Autor:
Rotem Ben-Hamo, Adi Jacob Berger, Nancy Gavert, Mendy Miller, Guy Pines, Roni Oren, Eli Pikarsky, Cyril H. Benes, Tzahi Neuman, Yaara Zwang, Sol Efroni, Gad Getz, Ravid Straussman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Predicting an individual's response to therapy is an important goal for precision medicine. Here, the authors use an algorithm that takes into account the interaction type and directionality of signalling pathways in protein–protein interactions an
Externí odkaz:
https://doaj.org/article/af440b4d64314959a421c75b7dfbd17b
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 445 (2021)
Aberrant activation of Wnt/β-catenin signaling and downstream β-catenin-TCF target genes is a hallmark of colorectal cancer (CRC) development. We identified the immunoglobulin-like cell adhesion receptor L1CAM (L1) as a target of β-catenin-TCF tra
Externí odkaz:
https://doaj.org/article/3c1d1e9bdb454177812f433bcfe7446c
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3552 (2021)
The overactivation of Wnt/β-catenin signaling is a hallmark of colorectal cancer (CRC) development. We identified the cell adhesion molecule L1CAM (L1) as a target of β-catenin-TCF transactivation in CRC cells. The overexpression of L1 in CRC cells
Externí odkaz:
https://doaj.org/article/29780ced58c44e59abb8bea49f37d85b
Autor:
Sylvie Robine, Avri Ben-Ze'ev, Daniel Louvard, Marick Laé, Gloria Jih, Klaus-Peter Janssen, Nancy Gavert, Marie Schoumacher, Danijela Vignjevic
Cancer cells become metastatic by acquiring a motile and invasive phenotype. This step requires remodeling of the actin cytoskeleton and the expression of exploratory, sensory organelles known as filopodia. Aberrant β-catenin-TCF target gene activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0409fa3207ca35dd24b1f8eb76c1193
https://doi.org/10.1158/0008-5472.c.6496059
https://doi.org/10.1158/0008-5472.c.6496059
Autor:
Avri Ben-Ze'ev, Eytan Domany, Daniel Notterman, Phillip Paty, Francis Barany, Thomas Brabletz, Michael Shtutman, Simone Spaderna, Shani Raveh, Michal Sheffer, Nancy Gavert
Supplementary Table 1 from Expression of L1-CAM and ADAM10 in Human Colon Cancer Cells Induces Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4002f615fda890a74b5d66255e5c98f2
https://doi.org/10.1158/0008-5472.22367934
https://doi.org/10.1158/0008-5472.22367934
Autor:
Sylvie Robine, Avri Ben-Ze'ev, Daniel Louvard, Marick Laé, Gloria Jih, Klaus-Peter Janssen, Nancy Gavert, Marie Schoumacher, Danijela Vignjevic
Supplementary Tables 1-2, Figure Legends 1-2, Methods from Fascin, a Novel Target of β-Catenin-TCF Signaling, Is Expressed at the Invasive Front of Human Colon Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0fe40972e5df984092dcb9307aeb01
https://doi.org/10.1158/0008-5472.22368672
https://doi.org/10.1158/0008-5472.22368672
Autor:
Avri Ben-Ze'ev, Eytan Domany, Daniel Notterman, Phillip Paty, Francis Barany, Thomas Brabletz, Michael Shtutman, Simone Spaderna, Shani Raveh, Michal Sheffer, Nancy Gavert
L1-CAM, a neuronal cell adhesion receptor, is also expressed in a variety of cancer cells. Recent studies identified L1-CAM as a target gene of β-catenin-T-cell factor (TCF) signaling expressed at the invasive front of human colon cancer tissue. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c253d67280030e824843c982bd5b305
https://doi.org/10.1158/0008-5472.c.6495744.v1
https://doi.org/10.1158/0008-5472.c.6495744.v1
Autor:
Sylvie Robine, Avri Ben-Ze'ev, Daniel Louvard, Marick Laé, Gloria Jih, Klaus-Peter Janssen, Nancy Gavert, Marie Schoumacher, Danijela Vignjevic
Supplementary Figure 2 from Fascin, a Novel Target of β-Catenin-TCF Signaling, Is Expressed at the Invasive Front of Human Colon Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e30201c62eb86701ed123b582e30387
https://doi.org/10.1158/0008-5472.22368675
https://doi.org/10.1158/0008-5472.22368675