Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nancy Fusco"'
Autor:
Steven E. Waggoner, Nancy Fusco, Deborah A. Smith, Vivian E. von Gruenigen, Susan Eaton, Anne M. Heugel, Robert Debernardo, Heidi Frasure
Publikováno v:
Anti-Cancer Drugs. 23:724-730
The aim of this study was to determine the dose of weekly oral topotecan that allows safe administration and to evaluate the pharmacokinetics of this dose in patients with recurrent gynecologic malignancies. The first cohort of patients received oral
Autor:
Nancy Fusco, Michael W. Sill, Paula M. Fracasso, Aaron H. Wolfson, Amina Ahmed, S. Diane Yamada, Ritu Salani, D. Scott McMeekin, Peter G. Rose
Publikováno v:
Gynecologic Oncology. 125:158-162
To determine the maximum tolerated dose (MTD) and acute dose-limiting toxicities (DLT) of intravenous topotecan administered with weekly cisplatin during pelvic radiation therapy in patients with locally advanced cervical cancer.Patients were treated
Autor:
Elisa Eldermire, Robert Debernardo, Heidi Frasure, Vivian E. von Gruenigen, Nancy Fusco, Susan Eaton, Steven E. Waggoner
Publikováno v:
Cancer. 116:4735-4743
BACKGROUND: The objective of this study was to compare the incidence of hand-foot syndrome (HFS) in patients who received pyridoxine versus placebo during pegylated liposomal doxorubicin (PLD) chemotherapy for recurrent ovarian, breast, or endometria
Publikováno v:
American Journal of Clinical Oncology. 31:476-480
The feasibility, safety, and preliminary efficacy of a second-line combination therapy for oral topotecan and pegylated liposomal doxorubicin in patients with platinum-resistant or refractory epithelial ovarian, peritoneal, or tubal carcinoma were in
Publikováno v:
Gynecologic Oncology. 107:274-279
Purpose To determine the maximum tolerated dose (MTD) of gemcitabine followed by cisplatin that can be administered weekly during pelvic radiation therapy in patients with locally advanced cervical cancer. Methods A phase I and feasibility study with
Publikováno v:
Gynecologic Oncology. 102:236-239
Preclinical models suggest synergy when topoisomerase I and II inhibitors are given sequentially, but not simultaneously. A phase I study was conducted in previously treated ovarian or peritoneal carcinoma to determine the tolerability (maximum numbe
Autor:
Peter G. Rose, Michael Rodriguez, William P. McGuire, Joan L. Walker, Nancy Fusco, Benjamin E. Greer
Publikováno v:
Gynecologic Oncology. 85:136-139
In an effort to explore second-line therapy in ovarian, peritoneal, and tubal carcinoma, a phase I trial combining prolonged oral etoposide and liposomal doxorubicin was conducted by the Gynecologic Oncology Group.Liposomal doxorubicin (20 mg/m(2)) w
Autor:
Anita Schwandt, Steven E. Waggoner, Afshin Dowlati, John Wright, Nancy Fusco, Pingfu Fu, Vivian E. von Gruenigen, Robert M. Wenham, Susan Eaton, Heidi Frasure
Publikováno v:
Investigational new drugs. 32(4)
Background/Purpose This study was designed to evaluate the response and toxicity of sorafenib alone or when combined with carboplatin and paclitaxel in patients with platinum-sensitive, recurrent ovarian cancer, fallopian tube cancer, or primary peri
Publikováno v:
Gynecologic Oncology. 82:323-328
The aim of this study was to evaluate the relative activity and tolerance of liposomal doxorubicin in recurrent ovarian, peritoneal, and tubal carcinoma at an initial dose of 40 or 50 mg/m(2) every 4 weeks.A retrospective single-institution study was