Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nancy Funk"'
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114288 (2014)
Here we show that designed transcription activator-like effectors (TALEs) that bind to defined areas of the interferon beta promoter are capable to induce IFN-beta expression and signaling in human cells. Importantly, TALE-mediated IFN-beta signaling
Externí odkaz:
https://doaj.org/article/a619913d851442849c733ed5ab90a026
Autor:
Conny Köhler, Tim Eiseler, Golsa Joodi, Peter Storz, Arsia Jamali, Nancy Funk, Thomas Seufferlein, Subbaiah Chary Nimmagadda
Publikováno v:
Journal of Biological Chemistry. 287:32367-32380
We here identify protein kinase D1 (PKD1) as a major regulator of anchorage-dependent and -independent growth of cancer cells controlled via the transcription factor Snail1. Using FRET, we demonstrate that PKD1, but not PKD2, efficiently interacts wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66709e6a9959736a8cbc913884c093d
https://doi.org/10.1074/jbc.m112.370999
https://doi.org/10.1074/jbc.m112.370999
Autor:
Rene Geissler, Nancy Funk, Jan van Lunzen, Jan Chemnitz, Martina Behrens, Sven-Erik Behrens, Ilona Hauber, Heidi Baum, Ivonne Renner, Helga Hofmann-Sieber, Annekatrin Richter, Jens Boch, Joachim Hauber
Publikováno v:
Virology. 486
The major obstacle to cure infections with human immunodeficiency virus (HIV-1) is integrated proviral genomes, which are not eliminated by antiretroviral therapies (ART). Treatment approaches with latency-reversing agents (LRAs) aim at inducing prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b31461908abb3ae035d2bfb9e1b0fc9
https://pubmed.ncbi.nlm.nih.gov/26474371
https://pubmed.ncbi.nlm.nih.gov/26474371
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114288 (2014)
PLoS ONE
PLoS ONE
Here we show that designed transcription activator-like effectors (TALEs) that bind to defined areas of the interferon beta promoter are capable to induce IFN-beta expression and signaling in human cells. Importantly, TALE-mediated IFN-beta signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038c16db719ac2c34a00343445152384
http://europepmc.org/articles/PMC4255017?pdf=render
http://europepmc.org/articles/PMC4255017?pdf=render