Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nancy Everds"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Purpose: Doxorubicin-related heart failure has been recognized as a serious complication of cancer chemotherapy. This paper describes a cardiovascular safety pharmacology study with chronic dosing of doxorubicin in a non-human primate model designed
Externí odkaz:
https://doaj.org/article/e91bf4247f974348b16e7b6b89a12adf
Autor:
Yudong D He, Christine M Karbowski, Jon Werner, Nancy Everds, Chris Di Palma, Yuan Chen, Marnie Higgins-Garn, Sandra Tran, Cynthia A Afshari, Hisham K Hamadeh
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88750 (2014)
Gene expression profiling is a tool to gain mechanistic understanding of adverse effects in response to compound exposure. However, little is known about how the common handling procedures of experimental animals during a preclinical study alter base
Externí odkaz:
https://doaj.org/article/0581c645f0774fb88b78327e2392f38d
Autor:
M Ann Mongan, Robert T Dunn, Steven Vonderfecht, Nancy Everds, Guang Chen, Cheng Su, Marnie Higgins-Garn, Yuan Chen, Cynthia A Afshari, Toni L Williamson, Linda Carlock, Christopher Dipalma, Suzanne Moss, Jeanine Bussiere, Charles Qualls, Yudong D He, Hisham K Hamadeh
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15595 (2010)
Genome-wide gene expression profiling has become standard for assessing potential liabilities as well as for elucidating mechanisms of toxicity of drug candidates under development. Analysis of microarray data is often challenging due to the lack of
Externí odkaz:
https://doaj.org/article/6f64d4f7790f4d45ad6e4ed7980b8a19
Autor:
Matthew Peach, Michelle M Chen, Feng Cai, Joanna Z Peng, Chongren Tang, Clarence Hale, Nancy Everds, V. D Fitzpatrick, Adam J Shaywitz, Mingyue Zhou, Ren Xu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
Introduction: Lecithin cholesterol acyltransferase (LCAT) esterifies free cholesterol to cholesteryl esters on the HDL particle and is considered a key component of reverse cholesterol transport. We have developed a recombinant human LCAT fusion prot