Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nancy E. LePard"'
Autor:
Momir Bosiljcic, Rachel A. Cederberg, Melisa J. Hamilton, Nancy E. LePard, Bryant T. Harbourne, Jenna L. Collier, Elizabeth C. Halvorsen, Rocky Shi, S. Elizabeth Franks, Ada Y. Kim, Judit P. Banáth, Mark Hamer, Fabio M. Rossi, Kevin L. Bennewith
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Abstract Background Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various tissues, and these cells can enhance metastatic tumor growth by several mechanisms. 4T1 murine mammary tumors are known to prod
Externí odkaz:
https://doaj.org/article/27a7a3ac6dc84010a63536a5241f3077
Autor:
James Jabalee, James Lawson, Cathie Garnis, Sara A. MacLellan, Christopher Td Dickman, Kevin L. Bennewith, Nancy E. LePard
Publikováno v:
Oncotarget
// Christopher T.D. Dickman 1 , James Lawson 1 , James Jabalee 1 , Sara A. MacLellan 1 , Nancy E. LePard 1 , Kevin L. Bennewith 1, 2 , Cathie Garnis 1, 3 1 Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Ca
Autor:
Mark Hamer, Fabio M.V. Rossi, Ada Y. Kim, Judit P. Banáth, Nancy E. LePard, Momir Bosiljcic, Jenna L. Collier, Bryant T. Harbourne, Rocky Shi, Melisa J. Hamilton, S. Elizabeth Franks, Rachel A. Cederberg, Kevin L. Bennewith, Elizabeth C. Halvorsen
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Breast Cancer Research, Vol 21, Iss 1, Pp 1-16 (2019)
Background Solid tumors produce proteins that can induce the accumulation of bone marrow-derived cells in various tissues, and these cells can enhance metastatic tumor growth by several mechanisms. 4T1 murine mammary tumors are known to produce granu
Autor:
Steven McKinney, Cristina E. Tognon, Thomas G. P. Grunewald, Nancy E. LePard, Debjit Khan, Franck Tirode, Olivier Delattre, Shamil Hajee, Gabriel Leprivier, Hongwei Cheng, Andrew I. Minchinton, Alastair H. Kyle, Jason N. Berman, Joan Mathers, Momir Bosiljcic, Poul H. Sorensen, Dale Corkery, Yuzhuo Wang, Graham Dellaire, Amal El-Naggar, Jennifer H.E. Baker, Kevin L. Bennewith, Gian Luca Negri, Syam Prakash Somasekharan, Chansey J. Veinotte
Publikováno v:
Cancer Cell. 27(5):682-697
SummaryMetastatic dissemination is the leading cause of death in cancer patients, which is particularly evident for high-risk sarcomas such as Ewing sarcoma, osteosarcoma, and rhabdomyosarcoma. Previous research identified a crucial role for YB-1 in
Autor:
Kevin L. Bennewith, Nancy E. LePard, Brennan J. Wadsworth, H. N. Lee, A.H. Young, Melisa J. Hamilton, Elizabeth C. Halvorsen, Jenna L. Collier, Natalie S. Firmino
Publikováno v:
Oncoimmunology. 5(6)
Regulatory T cells (Tregs) play a crucial physiological role in the regulation of immune homeostasis, although recent data suggest Tregs can contribute to primary tumor growth by suppressing antitumor immune responses. Tregs may also influence the de
Autor:
Nancy E. LePard, Melisa J. Hamilton, Elizabeth C. Halvorsen, Judit P. Banáth, Kevin L. Bennewith, Momir Bosiljcic, Victor W. Ho, Vivian Lam, Gerald Krystal
Publikováno v:
Oncotarget
SH2-containing-inositol-5'-phosphatase (SHIP) is a negative regulator of the phosphatidylinositol-3-kinase pathway in hematopoietic cells and limits the development of leukemias and lymphomas. The potential role of SHIP in solid tumor development and
Autor:
Ralph E. Durand, Nancy E. LePard
Publikováno v:
Radiotherapy and Oncology. 56:245-252
Background and purpose : Mitomycin C was one of the first chemotherapeutic agents to be shown to have preferential cytotoxicity toward hypoxic cells in vitro. Consequently, it has been used clinically with radiotherapy, and has stimulated considerabl
Autor:
Victor W. Ho, Judit P. Banáth, Nancy E. LePard, Kevin L. Bennewith, Momir Bosiljcic, Gerald Krystal, Elizabeth C. Halvorsen, Melisa J. Hamilton
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(1)
Myeloid-derived suppressor cells (MDSCs) are emerging as potential promoters of metastatic tumor growth, and there is interest in targeting immature MDSCs by inducing their differentiation into more mature myeloid cells. We used all-trans retinoic ac
Autor:
Judit P. Banáth, Gerald Krystal, Momir Bosiljcic, Melisa J. Hamilton, Denise C. McDougal, Jessica X. Jia, Nancy E. LePard, Kevin L. Bennewith
Publikováno v:
Cancer research. 71(14)
4T1 murine mammary carcinoma cells implanted in syngeneic Balb/c mice are increasingly being used in metastasis research, with some groups using this model to study tumor-induced accumulation of bone marrow–derived cells in metastatic target organs
Autor:
Ralph E. Durand, Nancy E LePard
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 42(2)
Background and purpose : Doxorubicin is usually an effective radiosensitizer in vitro, but in vivo reports have been more variable. We have examined potential explanations for those observations by comprehensively evaluating doxorubicin and radiation