Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Nancy E. Hynes"'
Autor:
Sabrina A. Vallone, Martín García Solá, Carolina Schere-Levy, Roberto P. Meiss, Gladys N. Hermida, Lewis A. Chodosh, Edith C. Kordon, Nancy E. Hynes, Albana Gattelli
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 3 (2022)
RET is a receptor tyrosine kinase with oncogenic potential in the mammary epithelium. Several receptors with oncogenic activity in the breast are known to participate in specific developmental stages. We found that RET is differentially expressed dur
Externí odkaz:
https://doaj.org/article/f52ccb7806184957a96b202402aab883
Autor:
Alessia Bottos, Dagmar Gotthardt, Jason W. Gill, Albana Gattelli, Anna Frei, Alexandar Tzankov, Veronika Sexl, Aleksandra Wodnar-Filipowicz, Nancy E. Hynes
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
JAK inhibitors are currently undergoing evaluation in clinical trials for advanced breast cancer. Here, the authors show that JAK pathway inhibition increases metastasis in mouse models of breast cancer by impairing NK anti-tumour activity and that t
Externí odkaz:
https://doaj.org/article/86420aae63434acfa4d1039c29037e97
Autor:
Matthias B. Moor, Barbara Haenzi, Finola Legrand, Robert Koesters, Nancy E. Hynes, Olivier Bonny
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Ablation of the Mediator of ErbB2-driven Cell Motility 1 (Memo1) in mice altered calcium homeostasis and renal calcium transporter abundance by an unknown mechanism. Here, we investigated the role of intrarenal Memo in renal calcium handling. We have
Externí odkaz:
https://doaj.org/article/77139af41fe94aa58d899136b0a2998c
Autor:
Jeffrey E. Segall, Carlos L. Arteaga, Nancy E. Hynes, Salvatore J. Coniglio, Pamela J. Boimel, Jeffrey Wyckoff, Dmitriy Kedrin
Purpose: The epidermal growth factor receptor (ERBB1) and related family member HER-2/neu (ERBB2) are often overexpressed in aggressive breast cancers and their overexpression is correlated with poor prognosis. Clinical studies using ERBB inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27293d47116574d0a247190ff31e8022
https://doi.org/10.1158/1078-0432.c.6517755
https://doi.org/10.1158/1078-0432.c.6517755
Autor:
Jeffrey E. Segall, Carlos L. Arteaga, Nancy E. Hynes, Salvatore J. Coniglio, Pamela J. Boimel, Jeffrey Wyckoff, Dmitriy Kedrin
Supplementary Movie S2 from ERBB1 and ERBB2 Have Distinct Functions in Tumor Cell Invasion and Intravasation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060ad3a16ef9408349059cdf2eed4502
https://doi.org/10.1158/1078-0432.22440423
https://doi.org/10.1158/1078-0432.22440423
Autor:
Jeffrey E. Segall, Carlos L. Arteaga, Nancy E. Hynes, Salvatore J. Coniglio, Pamela J. Boimel, Jeffrey Wyckoff, Dmitriy Kedrin
Supplementary Figures S1-S2 from ERBB1 and ERBB2 Have Distinct Functions in Tumor Cell Invasion and Intravasation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6879c6969bf8d26c889fb56dfdbb0dd9
https://doi.org/10.1158/1078-0432.22440429.v1
https://doi.org/10.1158/1078-0432.22440429.v1
Autor:
Nancy E. Hynes, Edward J. Oakeley, Debora Bonenfant, Johannes Voshol, Fabrizio Bianchi, Julien H. Dey
Supplementary Table 6 from Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c35c009911ab88527f67bdc6b7be3a8
https://doi.org/10.1158/0008-5472.22381661.v1
https://doi.org/10.1158/0008-5472.22381661.v1
Autor:
Nancy E. Hynes, Edward J. Oakeley, Debora Bonenfant, Johannes Voshol, Fabrizio Bianchi, Julien H. Dey
Supplementary Methods and Materials from Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::495d7ce74169e4e6f5a9d33d908f37e9
https://doi.org/10.1158/0008-5472.22381682.v1
https://doi.org/10.1158/0008-5472.22381682.v1
Autor:
Nancy E. Hynes, Edward J. Oakeley, Debora Bonenfant, Johannes Voshol, Fabrizio Bianchi, Julien H. Dey
Supplementary Figure 1 from Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a528ee8b4d885e309be521a8716997c7
https://doi.org/10.1158/0008-5472.22381703
https://doi.org/10.1158/0008-5472.22381703
Autor:
Nancy E. Hynes, Edward J. Oakeley, Debora Bonenfant, Johannes Voshol, Fabrizio Bianchi, Julien H. Dey
Supplementary Figure Legends 1-6,Table Legends 1-7 from Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39cf504d5ad808451e49f59e27271cb5
https://doi.org/10.1158/0008-5472.22381685.v1
https://doi.org/10.1158/0008-5472.22381685.v1