Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Nancy E. Brutsche"'
Autor:
Annie J. Xu, Mark J. Niciu, Nancy B. Lundin, David A. Luckenbaugh, Dawn F. Ionescu, Erica M. Richards, Jennifer L. Vande Voort, Elizabeth D. Ballard, Nancy E. Brutsche, Rodrigo Machado-Vieira, Carlos A. Zarate
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
Ketamine and lithium both inhibit glycogen synthase kinase 3. In addition, lithium and ketamine have synergistic antidepressant-like effects at individually subeffective doses in rodents. We hypothesized that ketamine’s antidepressant effects would
Externí odkaz:
https://doaj.org/article/f5c2b1156ceb4665afe4763b0eb1e260
Autor:
Dawn F. Ionescu, Rodrigo Machado-Vieira, David A. Luckenbaugh, Nancy E. Brutsche, Lawrence Park, Carlos A. Zarate, Nicolas D. Iadarola, Francis J. McMahon, Marc S. Lener, Minkyung Park, Mark J. Niciu, Nirmala Akula, Dipavo Banerjee, Elizabeth D. Ballard, Allison C. Nugent
Publikováno v:
Journal of Psychopharmacology. 31:1570-1577
This study sought to reproduce, in a larger sample, previous findings of a correlation between smaller raw 3-Tesla (3T) hippocampal volumes and improved antidepressant efficacy of ketamine in individuals with major depressive disorder (MDD). A second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7af447527134e5515c60a5df3d3799
https://doi.org/10.1177/0269881117732514
https://doi.org/10.1177/0269881117732514
Autor:
Jennifer W. Evans, Lawrence Park, Allison C. Nugent, Joanna Szczepanik, Nancy E. Brutsche, Carlos A. Zarate
Background The symptoms of major depressive disorder (MDD) are rapidly alleviated by administration of a single dose of the glutamatergic modulator ketamine. However, few studies have investigated the potential sustained neural effects of this agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69ff8155ddfc22e6f3447d9df629839
https://europepmc.org/articles/PMC6093808/
https://europepmc.org/articles/PMC6093808/
Autor:
Ruin Moaddel, Nancy E. Brutsche, Lawrence Park, Allison C. Nugent, Elizabeth D. Ballard, Carlos A. Zarate, Todd D. Gould
Publikováno v:
Molecular psychiatry
Ketamine’s mechanism of action was assessed using gamma power from magnetoencephalography (MEG) as a proxy measure for homeostatic balance in 35 unmedicated subjects with major depressive disorder (MDD) and 25 healthy controls enrolled in a double-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc9d4df9beba2640bc7c28d81030022
http://europepmc.org/articles/PMC6111001
http://europepmc.org/articles/PMC6111001
Autor:
Lawrence Park, Nancy E. Brutsche, Cristan Farmer, David A. Luckenbaugh, Bridget Shovestul, Brittany A. Jaso, Mark J. Niciu, Elizabeth D. Ballard, Carlos A. Zarate
Publikováno v:
Journal of affective disorders. 232
Background Ketamine induces rapid and robust antidepressant effects, and many patients also describe dissociation, which is associated with antidepressant response. This follow-up study investigated whether antidepressant efficacy is uniquely related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970ef02f03eb33e01d952829b57fc5a2
https://pubmed.ncbi.nlm.nih.gov/29501990
https://pubmed.ncbi.nlm.nih.gov/29501990
Autor:
Erica M. Richards, David A. Luckenbaugh, Annie J. Xu, Mark J. Niciu, Jennifer L. Vande Voort, Nancy E. Brutsche, Dawn F. Ionescu, Rodrigo Machado-Vieira, Elizabeth D. Ballard, Nancy B. Lundin, Carlos A. Zarate
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
Neural Plasticity
Neural Plasticity
Ketamine and lithium both inhibit glycogen synthase kinase 3. In addition, lithium and ketamine have synergistic antidepressant-like effects at individually subeffective doses in rodents. We hypothesized that ketamine’s antidepressant effects would
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52d3586e4d9d03cb1d70eca952b24a0
https://doi.org/10.1155/2015/858251
https://doi.org/10.1155/2015/858251
Autor:
Erica M. Richards, Elizabeth D. Ballard, Lawrence Park, Kathleen E. Wills, Mark J. Niciu, Nancy E. Brutsche, David A. Luckenbaugh, Níall Lally, Tessa L. Walls, Carlos A. Zarate, Rezvan Ameli
Background Identifying clinical correlates associated with reduced suicidal ideation may highlight new avenues for the treatment of suicidal thoughts. Anhedonia occurs across psychiatric diagnoses and has been associated with specific neural circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5856a89783e124de7bcdcac642f11e7a
https://europepmc.org/articles/PMC5515296/
https://europepmc.org/articles/PMC5515296/
Autor:
Coral Barbas, Michel Bernier, Ruin Moaddel, Nancy E. Brutsche, Irving W. Wainer, Alma Villaseñor, Ying Xie, David A. Luckenbaugh, Antonia García, Marc C. Torjman, Carlos A. Zarate, Rodrigo Machado-Vieira, Anuradha Ramamoorthy, María M. Lorenzo
Publikováno v:
Psychopharmacology. 232:399-409
(R,S)-ketamine is a rapid and effective antidepressant drug that produces a response in two thirds of patients with treatment-resistant depression (TRD). The underlying biochemical differences between a (R,S)-ketamine responder (KET-R) and non-respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9eba397d5fc754c7655eef00a8eba2
https://doi.org/10.1007/s00213-014-3669-0
https://doi.org/10.1007/s00213-014-3669-0
Autor:
David A. Luckenbaugh, Neal M. Nolan, Dawn F. Ionescu, Nancy E. Brutsche, Sara Guevara, Erica M. Richards, Rodrigo Machado-Vieira, Mark J. Niciu, Carlos A. Zarate
Publikováno v:
The Journal of Clinical Psychiatry. 75:e417-e423
The N-methyl-D-aspartate receptor antagonist ketamine has rapid antidepressant effects in treatment-resistant major depressive disorder (MDD) and bipolar depression. Clinical predictors may identify those more likely to benefit from ketamine within c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318bcb220982d47b3a46594b929fd97f
https://doi.org/10.4088/jcp.13m08698
https://doi.org/10.4088/jcp.13m08698
Autor:
Wayne C. Drevets, Carlos A. Zarate, Paul J. Carlson, Nancy Diazgranados, Allison C. Nugent, Peter Herscovitch, Husseini K. Manji, Lobna Ibrahim, David A. Luckenbaugh, Nancy E. Brutsche
Publikováno v:
Biological Psychiatry. 73:1213-1221
Background Multiple lines of evidence support a role for the glutamatergic system in the pathophysiology of major depressive disorder (MDD). Ketamine, an N-methyl-D-aspartate antagonist, rapidly improves depressive symptoms in individuals with treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1c29f8c628ff69dfdcbc33acaca6ca3
https://doi.org/10.1016/j.biopsych.2013.02.008
https://doi.org/10.1016/j.biopsych.2013.02.008