Zobrazeno 1 - 10
of 592
pro vyhledávání: '"Nancy E Lane"'
Autor:
Sita M A Bierma-Zeinstra, Stefan Kluzek, David Felson, Graeme Jones, Rintje Agricola, Nigel K Arden, Joshua Heerey, Andrea B Mosler, Flavia Cicuttini, Jos Runhaar, M Nevitt, Nancy E Lane, John A Lynch, Harrie Weinans, Timothy F Cootes, Kay Crossley, Cindy G Boer, Willem Paul Gielis, Edwin Oei, Michiel M A van Buuren, Noortje S Riedstra, Myrthe A van den Berg, Fleur D E M Boel, Harbeer Ahedi, Vahid Arbabi, Claudia Lindner, J Van Meurs, Amanda E Nelson, Jinchi Tang
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Purpose Hip osteoarthritis (OA) is a major cause of pain and disability worldwide. Lack of effective therapies may reflect poor knowledge on its aetiology and risk factors, and result in the management of end-stage hip OA with costly joint replacemen
Externí odkaz:
https://doaj.org/article/2950d568396a49abbc5b2d988c32ccbe
Autor:
Alanna M. Dubrovsky, Jeffrey S. Nyman, Sasidhar Uppuganti, Kenneth J. Chmiel, Donald B. Kimmel, Nancy E Lane
Publikováno v:
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
ABSTRACT Glucocorticoids increase bone fragility in patients in a manner that is underestimated by bone mass measurement. This study aimed to determine if the adult mouse could model this bone strength/bone mass discrepancy. Forty‐two 13‐week‐o
Externí odkaz:
https://doaj.org/article/6a6b8e471d804f48b92330ae0c960cc9
Autor:
Christopher N Kaufmann, Jian Shen, Gina N Woods, Nancy E Lane, Katie L Stone, Deborah M Kado, Osteoporotic Fractures in Men (MrOS) Study Research Group
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228638 (2020)
ObjectivesHyperkyphosis is associated with restricted pulmonary function and posture, potentially contributing to poor sleep. A previous study reported older women with hyperkyphosis had worse self-reported sleep quality, but it is less clear if this
Externí odkaz:
https://doaj.org/article/3ebb2fcdf84e4bd49827f471fd8d830c
Autor:
Pradeep Suri, Melody R Palmer, Yakov A Tsepilov, Maxim B Freidin, Cindy G Boer, Michelle S Yau, Daniel S Evans, Andrea Gelemanovic, Traci M Bartz, Maria Nethander, Liubov Arbeeva, Lennart Karssen, Tuhina Neogi, Archie Campbell, Dan Mellstrom, Claes Ohlsson, Lynn M Marshall, Eric Orwoll, Andre Uitterlinden, Jerome I Rotter, Gordan Lauc, Bruce M Psaty, Magnus K Karlsson, Nancy E Lane, Gail P Jarvik, Ozren Polasek, Marc Hochberg, Joanne M Jordan, Joyce B J Van Meurs, Rebecca Jackson, Carrie M Nielson, Braxton D Mitchell, Blair H Smith, Caroline Hayward, Nicholas L Smith, Yurii S Aulchenko, Frances M K Williams
Publikováno v:
PLoS Genetics, Vol 14, Iss 9, p e1007601 (2018)
Back pain is the #1 cause of years lived with disability worldwide, yet surprisingly little is known regarding the biology underlying this symptom. We conducted a genome-wide association study (GWAS) meta-analysis of chronic back pain (CBP). Adults o
Externí odkaz:
https://doaj.org/article/e7405eec3ba84a9f9ddf6c053f265a3f
Autor:
Kwanghoon Lee, Marina Banuls-Mirete, Alecio F. Lombardi, Alexander I.B. Posis, Eric Y. Chang, Nancy E. Lane, Monica Guma
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-9 (2024)
Abstract Objectives Adipose tissue has been associated with knee osteoarthritis (KOA) pathogenesis, but the longitudinal changes in adipose tissue with KOA progression have not been carefully evaluated. This study aimed to determine if longitudinal c
Externí odkaz:
https://doaj.org/article/ef9f80152e8140819338a8102365dfad
Autor:
Anjum Shaik, Kristoffer Larsen, Nancy E. Lane, Chen Zhao, Kuan-Jui Su, Joyce H. Keyak, Qing Tian, Qiuying Sha, Hui Shen, Hong-Wen Deng, Weihua Zhou
Publikováno v:
Bone Reports, Vol 22, Iss , Pp 101805- (2024)
Hip fractures present a significant healthcare challenge, especially within aging populations, where they are often caused by falls. These fractures lead to substantial morbidity and mortality, emphasizing the need for timely surgical intervention. D
Externí odkaz:
https://doaj.org/article/72ff07d14f2343cf963820df19849a0d
Autor:
Martha C Castaño-Betancourt, Dan S Evans, Yolande F M Ramos, Cindy G Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B Kraus, Michelle S Yau, Braxton D Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A Maciewicz, Nigel Arden, Rob G H H Nelissen, Margreet Kloppenburg, Joanne M Jordan, Michael C Nevitt, Eline P Slagboom, Deborah J Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D Spector, Andre G Uitterlinden, Nancy E Lane, Ingrid Meulenbelt, Ana M Valdes, Joyce B J van Meurs
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006260 (2016)
Osteoarthritis is one of the most frequent and disabling diseases of the elderly. Only few genetic variants have been identified for osteoarthritis, which is partly due to large phenotype heterogeneity. To reduce heterogeneity, we here examined carti
Externí odkaz:
https://doaj.org/article/346cded1a0c64f81b7b42090748bb1f4
Autor:
Pia M Jungmann, Thomas Baum, Michael C Nevitt, Lorenzo Nardo, Alexandra S Gersing, Nancy E Lane, Charles E McCulloch, Ernst J Rummeny, Thomas M Link
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0166865 (2016)
Anterior cruciate ligaments (ACL) injuries represent a major risk factor for early osteoarthritis (OA).To evaluate the prevalence and 4-year progression of knee OA measured with 3T MR-imaging in individuals with ruptured, reconstructed or normal ACL
Externí odkaz:
https://doaj.org/article/c37e8163633243ed95f892aa974c3867
Autor:
Wei Yao, Weiwei Dai, Mohammad Shahnazari, Aaron Pham, Zhiqiang Chen, Haiyan Chen, Min Guan, Nancy E Lane
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11410 (2010)
Augmentation of the peak bone mass (PBM) may be one of the most effective interventions to reduce the risk of developing osteoporosis later in life; however treatments to augment PBM are currently limited. Our study evaluated whether a greater PBM co
Externí odkaz:
https://doaj.org/article/be00cb330d9147798888044dafa9e095
Autor:
Yalei Wu, James Torchia, Wei Yao, Nancy E Lane, Lewis L Lanier, Mary C Nakamura, Mary Beth Humphrey
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e586 (2007)
Immunoreceptor tyrosine-based activation motif (ITAM) signaling mediated by DAP12 or Fcepsilon receptor Igamma chain (FcRgamma) have been shown to be critical for osteoclast differentiation and maturation under normal physiological conditions. Their
Externí odkaz:
https://doaj.org/article/b27c95a9156d4aa4a063810e82357031