Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nancy E, Phillips"'
Autor:
Aldo A. Rossini M.D., David C. Parker, Nancy E. Phillips, Fiona H. Durie, Randolph J. Noelle, John P. Mordes, Dale L. Greiner
Publikováno v:
Cell Transplantation, Vol 5 (1996)
T-cell dependent activation of resting B cells involves the interaction of gp39 on T cells with its receptor, CD40, on B cells. We administered either a combination of T-cell-depleted splenic lymphocytes and anti-gp39 monoclonal antibody or antibody
Externí odkaz:
https://doaj.org/article/9596d2d3f0274544be998037a7d110f5
Autor:
J Laning, Michael A. Brehm, Nancy E. Phillips, Laurence D. Covassin, Leonard D. Shultz, D L Langevin, R Abdi
Publikováno v:
Clinical and Experimental Immunology. 166:269-280
Summary Graft-versus-host disease (GVHD) is a life-threatening complication of human allogeneic haematopoietic stem cell transplantation. Non-obese diabetic (NOD)-scid IL2rγnull (NSG) mice injected with human peripheral blood mononuclear cells (PBMC
Autor:
Michael P. Czech, Nancy E. Phillips, Aldo A. Rossini, Dale L. Greiner, Kenneth D. Bishop, John P. Mordes, John E. Harris
Publikováno v:
Cellular Immunology. 256:86-91
Recent studies have implicated the cell surface receptor Programmed Death-1 (PD-1) in numerous models of T cell anergy, though the specific mechanisms by which the PD-1 signal maintains tolerance is not clear. We demonstrate that the depletion of PD-
Autor:
Dale L. Greiner, Nancy E. Phillips, Raymond M. Welsh, Evelyn A. Kurt-Jones, John P. Mordes, Thomas B. Thornley, Thomas G. Markees, Leonard D. Shultz, Kapil Bahl, Aldo A. Rossini, Michael A. Brehm, Britte C. Beaudette-Zlatanova
Publikováno v:
The Journal of Immunology. 179:6620-6629
TLR activation of innate immunity prevents the induction of transplantation tolerance and shortens skin allograft survival in mice treated with costimulation blockade. The mechanism by which TLR signaling mediates this effect has not been clear. We n
Autor:
Jean Leif, Aldo A. Rossini, Michael C. Appel, Dale L. Greiner, Scott J. Banuelos, Amy Cuthbert, Nancy E. Phillips, Thomas G. Markees, Leonard D. Shultz, John P. Mordes
Publikováno v:
Transplantation. 78:660-667
Background. Donor-specific transfusion (DST) and a brief course of anti-CD 154 monoclonal antibody (mAb) induces permanent islet and prolonged skin allograft survival in mice. Induction of skin allograft survival requires the presence of CD4 + cells
Autor:
Aldo A. Rossini, Dale L. Greiner, John P. Mordes, Neal N. Iwakoshi, Nicole A. Turgeon, Raymond M. Welsh, Nancy E. Phillips, William C. Meyers
Publikováno v:
Journal of Surgical Research. 93:63-69
Background. Treatment with a single donor-specific transfusion (DST) plus a brief course of anti-CD154 monoclonal antibody (mAb) prolongs skin allograft survival in mice. It is known that prolongation of allograft survival by this method depends in p
Autor:
Bruce A. Woda, Nancy E. Phillips, Thomas G. Markees, Christopher Sorli, David V. Serreze, Dale L. Greiner, Ethel J. Gordon, Aldo A. Rossini, Randolph J. Noelle, Leonard D. Shultz, John P. Mordes
Publikováno v:
Diabetes. 48:967-974
A protocol consisting of a single donor-specific transfusion (DST) plus a brief course of anti-CD154 monoclonal antibody (anti-CD40 ligand mAb) induces permanent islet allograft survival in chemically diabetic mice, but its efficacy in mice with auto
Autor:
Aldo A. Rossini, John P. Mordes, Dale L. Greiner, Nancy E. Phillips, Thomas G. Markees, Ethel J. Gordon
Publikováno v:
Transplantation Proceedings. 31:629-632
Autor:
Thomas G. Markees, Dale L. Greiner, Leonard D. Shultz, Randolph J. Noelle, Aldo A. Rossini, John P. Mordes, Nancy E. Phillips
Publikováno v:
Transplantation. 64:329-335
Combined treatment with antibody against CD40 ligand and one transfusion of donor splenocytes prolonged survival of fully mismatched BALB/c skin allografts on C57BL/6 recipients, with approximately 20% of grafts surviving > 100 days. In vitro allores
Autor:
Michael A. Brehm, Rita Bortell, Rabia Bajwa, Nicole M. Roy, Laurence D. Covassin, Waldemar J. Racki, Dale L. Greiner, Chaoxing Yang, Philip diIorio, Philipp Gut, Kathryn L. Lipson, Didier Y.R. Stainier, Agata Jurczyk, Aldo A. Rossini, Nancy E. Phillips
Publikováno v:
General and comparative endocrinology. 170(2)
Zebrafish embryos are emerging as models of glucose metabolism. However, patterns of endogenous glucose levels, and the role of the islet in glucoregulation, are unknown. We measured absolute glucose levels in zebrafish and mouse embryos, and demonst