Výsledky vyhledávání - "Nancy Dionne"

Functional organization of anMbpenhancer exposes striking transcriptional regulatory diversity within myelinating glia

Autor: Eric Denarier, Thomas J. Hudson, Bente Finsen, Nancy Dionne, Tanja Kuhlmann, Maia V. Kokoeva, Kathy Siminovitch, Hana Friedman, Régen Drouin, Alan C. Peterson, Samar Dib

Publikováno v: Glia. 64:175-194

In mammals, large caliber axons are ensheathed by myelin, a glial specialization supporting axon integrity and conferring accelerated and energy-efficient action potential conduction. Myelin basic protein (MBP) is required for normal myelin elaborati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e610fd22b76b0868615a612e3db372fe
https://doi.org/10.1002/glia.22923

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Functional organization of an Mbp enhancer exposes striking transcriptional regulatory diversity within myelinating glia

Autor: Nancy, Dionne, Samar, Dib, Bente, Finsen, Eric, Denarier, Tanja, Kuhlmann, Régen, Drouin, Maia, Kokoeva, Thomas J, Hudson, Kathy, Siminovitch, Hana C, Friedman, Alan C, Peterson

Publikováno v: Glia. 64(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30813d9f74e954bd54ba13004981383a
https://pubmed.ncbi.nlm.nih.gov/26507463

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Regulatory modules function in a non-autonomous manner to control transcription of the mbp gene

Autor: Nancy Dionne, Hana H. Friedman, Eric Denarier, Mélissa Beaudoin, Alan C. Peterson, Samar Dib

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2011, 39 (7), pp.2548-58. ⟨10.1093/nar/gkq1160⟩

International audience; Multiple regulatory modules contribute to the complex expression programs realized by many loci. Although long thought of as isolated components, recent studies demonstrate that such regulatory sequences can physically associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340b734e09a0cec5ef8d4c0e75abc532
https://www.hal.inserm.fr/inserm-00638853/file/Dib-Regulatory-_2011-AE.pdf

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Functional organization of a Schwann cell enhancer

Autor: Alan C. Peterson, Hana C. Friedman, Samar Dib, Eric Denarier, Pierre Lepage, Hooman F. Farhadi, Régen Drouin, Thomas J. Hudson, Reza Forghani, Nancy Dionne

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2005, 25 (48), pp.11210-7. ⟨10.1523/JNEUROSCI.2596-05.2005⟩

Myelin basic protein (MBP) gene expression is conferred in oligodendrocytes and Schwann cells by different upstream enhancers. In Schwann cells, expression is controlled by a 422 bp enhancer lying -9 kb from the gene. We show here that it contains 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5eca68cf7bdc1653d4b13477ecc822
https://www.hal.inserm.fr/inserm-00380194

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Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity

Autor: Nancy Dionne, Andras Nagy, Louis Lefebvre, Jana Karaskova, Jeremy A. Squire

Publikováno v: Nature genetics. 27(3)

Embryonic stem cells offer unprecedented opportunities for random or targeted genome alterations in the mouse. We present here an efficient strategy to create chromosome-specific loss of heterozygosity in embryonic stem cells. The combination of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f8322f6e41e408a6a8d689581bdfa4
https://pubmed.ncbi.nlm.nih.gov/11242104

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