Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nancy Desroches"'
Autor:
Sudha Bhavanam, Dennis Kunimoto, Rakesh Kumar, Amogh Agrawal, Naveen C. Srivastav, Neeraj Shakya, Nancy Desroches, Chris Tse
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1091-1094
Several 5-alkyl (or halo)-3′-azido (amino or halo) analogs of pyrimidine nucleosides have been synthesized and evaluated against Mycobacterium bovis , Mycobacterium tuberculosis and Mycobacterium avium . Among these compounds, 3′-azido-5-ethyl-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e9b19d23a6c0c0b26bd8e24bfb24b7
https://doi.org/10.1016/j.bmcl.2011.11.114
https://doi.org/10.1016/j.bmcl.2011.11.114
Autor:
Naveen C. Srivastav, Rakesh Kumar, Babita Agrawal, Dennis Kunimoto, Nancy Desroches, Neeraj Shakya
Publikováno v:
Journal of Medicinal Chemistry. 53:4130-4140
Tuberculosis (TB) is a major health problem worldwide. We herein report a new class of pyrimidine nucleosides as potent inhibitors of Mycobacterium tuberculosis (M. tuberculosis). Various 2'- or 3'-halogeno derivatives of pyrimidine nucleosides conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499f3f8fb5e61f38889b32e7a9cc0743
https://doi.org/10.1021/jm100165w
https://doi.org/10.1021/jm100165w
Autor:
Nancy Desroches, Tracey Manning, Rakesh K. Kumar, Monika Johar, Christopher Tse, Dennis Kunimoto, Babita Agrawal
Publikováno v:
Journal of Medicinal Chemistry. 50:3696-3705
The resurgence of tuberculosis and the emergence of multiple-drug-resistant strains of Mycobacteria necessitate the search for new classes of antimycobacterial agents. We synthesized a series of 1-beta-D-2'-arabinofuranosyl and 1-(2'-deoxy-2'-fluoro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bca01aefe0c944393d0b704da3e6166
https://doi.org/10.1021/jm0703901
https://doi.org/10.1021/jm0703901
Autor:
Chris Tse, Neeraj Shakya, Babita Agrawal, Sudha Bhavanam, Naveen C. Srivastav, Rakesh K. Kumar, Nancy Desroches, Dennis Kunimoto
Publikováno v:
Bioorganicmedicinal chemistry. 20(13)
Discovery of novel antimycobacterial compounds that work on distinctive targets and by diverse mechanisms of action is urgently required for the treatment of mycobacterial infections due to the emerging global health threat of tuberculosis. We have i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717a5d750bed87d5f9c5a086bc19bc02
https://pubmed.ncbi.nlm.nih.gov/22664188
https://pubmed.ncbi.nlm.nih.gov/22664188
Autor:
Monika, Johar, Tracey, Manning, Christopher, Tse, Nancy, Desroches, B, Agrawal, Dennis Y, Kunimoto, Rakesh, Kumar
Publikováno v:
Journal of medicinal chemistry. 50(15)
The resurgence of tuberculosis and the emergence of multiple-drug-resistant strains of Mycobacteria necessitate the search for new classes of antimycobacterial agents. We synthesized a series of 1-beta-D-2'-arabinofuranosyl and 1-(2'-deoxy-2'-fluoro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1aa54f34a983033431230c32965a4772
https://pubmed.ncbi.nlm.nih.gov/17602465
https://pubmed.ncbi.nlm.nih.gov/17602465
Autor:
Monika Johar, Tracey Manning, Christopher Tse, Nancy Desroches, B. Agrawal, Dennis Y. Kunimoto, Rakesh Kumar
Publikováno v:
Journal of Medicinal Chemistry; Jul2007, Vol. 50 Issue 15, p3696-3705, 10p