Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Nancy D Dalton"'
Autor:
Adam J Pollak, Canzhao Liu, Aparna Gudlur, Joshua E Mayfield, Nancy D Dalton, Yusu Gu, Ju Chen, Joan Heller Brown, Patrick G Hogan, Sandra E Wiley, Kirk L Peterson, Jack E Dixon
Publikováno v:
eLife, Vol 7 (2018)
Ca2+ signaling is important for many cellular and physiological processes, including cardiac function. Although sarcoplasmic reticulum (SR) proteins involved in Ca2+ signaling have been shown to be phosphorylated, the biochemical and physiological ro
Externí odkaz:
https://doaj.org/article/ecc097f1b4894d6997ab24d9a2cc0ed7
Autor:
Angela K Peter, William H Bradford, Nancy D Dalton, Yusu Gu, Chieh-Ju Chao, Kirk L Peterson, Kirk U Knowlton
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159971 (2016)
To address the question as to whether echocardiographic and/or microcomputed tomography (microCT) analysis can be utilized to assess the extent of Coxsackie B virus (CVB) induced myocarditis in the absence of left ventricular dysfunction in the mouse
Externí odkaz:
https://doaj.org/article/baa54f2a2d1b4b05af64babc26054255
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93638 (2014)
Ankrd1/CARP, Ankrd2/Arpp, and Ankrd23/DARP belong to a family of stress inducible ankyrin repeat proteins expressed in striated muscle (MARPs). The MARPs are homologous in structure and localized in the nucleus where they negatively regulate gene exp
Externí odkaz:
https://doaj.org/article/7abcde0b50ed4b8282237dd5338428e7
Autor:
Wilbur Y W Lew, Evelyn Bayna, Erminia Dalle Molle, Nancy D Dalton, N Chin Lai, Valmik Bhargava, Vincent Mendiola, Paul Clopton, Tong Tang
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61057 (2013)
BACKGROUND: Circulating subclinical lipopolysaccharide (LPS) occurs in health and disease. Ingesting high fatty meals increases LPS that cause metabolic endotoxemia. Subclinical LPS in periodontal disease may impair endothelial function. The heart ma
Externí odkaz:
https://doaj.org/article/2f192b2ce77d49b5a53c4524d695e70c
Autor:
Aboli A Rane, Joyce S Chuang, Amul Shah, Diane P Hu, Nancy D Dalton, Yusu Gu, Kirk L Peterson, Jeffrey H Omens, Karen L Christman
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21571 (2011)
Several injectable materials have been shown to preserve or improve cardiac function as well as prevent or slow left ventricular (LV) remodeling post-myocardial infarction (MI). However, it is unclear as to whether it is the structural support or the
Externí odkaz:
https://doaj.org/article/15d4b78546d64eaba501e4add3221a59
Autor:
Shih-hsin Kan, Jeffrey Y. Huang, Jerry Harb, Allisandra Rha, Nancy D. Dalton, Chloe Christensen, Yunghang Chan, Jeremy Davis-Turak, Jonathan Neumann, Raymond Y. Wang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Pompe disease, an autosomal recessive disorder caused by deficient lysosomal acid α-glucosidase (GAA), is characterized by accumulation of intra-lysosomal glycogen in skeletal and oftentimes cardiac muscle. The c.1935C>A (p.Asp645Glu) varia
Externí odkaz:
https://doaj.org/article/23464ddf02a94fbeb809115494e48be1
Autor:
Kyohei Fujita, Patrick Desmond, Jordan Blondelle, Matúš Soták, Meenu Rohini Rajan, Madison Clark, Eric Esteve, Yunghang Chan, Yusu Gu, Valeria Marrocco, Nancy D. Dalton, Majid Ghassemian, Aryanne Do, Matthew Klos, Kirk L. Peterson, Farah Sheikh, Yoshitake Cho, Emma Börgeson, Stephan Lange
Muscle proteins of the obscurin protein family play important roles in sarcomere organization, sarcoplasmic reticulum (SR) and T-tubule architecture and function. However, their precise molecular functions and redundancies between protein family memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b69e46f3c2e8df168bf0d6dd05fec4c
https://doi.org/10.1101/2022.08.24.505098
https://doi.org/10.1101/2022.08.24.505098
Autor:
Yusu Gu, Darren E. Casteel, Shunhui Zhuang, Nancy D. Dalton, Gerburg K. Schwaerzer, Wolfgang H. Dillmann, Renate B. Pilz, Federico Cividini, Hema Kalyanaraman, Kirk L. Peterson, Gerry R. Boss
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: Heart failure is associated with high morbidity and mortality, and new therapeutic targets are needed. Preclinical data suggest that pharmacological activation of protein kinase G (PKG) can reduce maladaptive ventricular remod
Autor:
Andrew D. McCulloch, Angela K. Peter, Debbie Ferng, Kirk U. Knowlton, Yunghang Chan, Selina Manying Huang, Matthew Klos, Hongqiang Cheng, Yusu Gu, Robert S. Ross, Ju Chen, Ruixia Li, Jordan Kelly Towne, Kirk L. Peterson, Jianlin Zhang, Nancy D. Dalton, Kevin P. Vincent
Publikováno v:
Circ Res
Circulation research, vol 127, iss 2
Circulation research, vol 127, iss 2
Rationale: ZO-1 (Zonula occludens-1), a plasma membrane-associated scaffolding protein regulates signal transduction, transcription, and cellular communication. Global deletion of ZO-1 in the mouse is lethal by embryonic day 11.5. The function of ZO-
Autor:
Emilie K. Sandfeld, Shih-hsin Kan, Jeremy Davis-Turak, Nancy D. Dalton, Raymond Y. Wang, Jon Neumann, Jeffrey Y. Huang, Anthony D. Rangel, Yunghang Chan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, vol 10, iss 1
The goal of this study is to generate and characterize a knock-in model of Pompe disease (PD) – a rare, progressive, fatal disorder primarily affecting the cardiac and musculoskeletal systems. While a murine model of PD exists, it bears a Cre/loxP