Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Nancy Chiang"'
2
Akademický článek
A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies
Autor: Rajesh Vij, Zhonghua Lin, Nancy Chiang, Jean-Michel Vernes, Kelly M. Storek, Summer Park, Joyce Chan, Y. Gloria Meng, Laetitia Comps-Agrar, Peng Luan, Sophia Lee, Kellen Schneider, Jack Bevers, Inna Zilberleyb, Christine Tam, Christopher M. Koth, Min Xu, Avinash Gill, Marcy R. Auerbach, Peter A. Smith, Steven T. Rutherford, Gerald Nakamura, Dhaya Seshasayee, Jian Payandeh, James T. Koerber
Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Outer membrane proteins (OMPs) in Gram-negative bacteria are essential for a number of cellular functions including nutrient transport and drug efflux. Escherichia coli BamA is an essential component of the OMP β-barrel assembly machinery a
Externí odkaz: https://doaj.org/article/987be71cec3148fcbac3acf988d53af6
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3
Akademický článek
A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action
Autor: Ning Chai, Lee R. Swem, Summer Park, Gerald Nakamura, Nancy Chiang, Alberto Estevez, Rina Fong, Lynn Kamen, Elviza Kho, Mike Reichelt, Zhonghua Lin, Henry Chiu, Elizabeth Skippington, Zora Modrusan, Jeremy Stinson, Min Xu, Patrick Lupardus, Claudio Ciferri, Man-Wah Tan
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Influenza B virus (IBV) co-circulates with influenza A virus to cause annual epidemics. Here, Chaiet al. isolate a human monoclonal antibody that binds to a conserved epitope in the viral HA protein, neutralizes IBV strains in vitro, and protects mic
Externí odkaz: https://doaj.org/article/d697ead9ca194b4d8f53f1f10eadf047
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4
Akademický článek
Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD
Autor: Kelly M Storek, Joyce Chan, Rajesh Vij, Nancy Chiang, Zhonghua Lin, Jack Bevers III, Christopher M Koth, Jean-Michel Vernes, Y Gloria Meng, JianPing Yin, Heidi Wallweber, Olivier Dalmas, Stephanie Shriver, Christine Tam, Kellen Schneider, Dhaya Seshasayee, Gerald Nakamura, Peter A Smith, Jian Payandeh, James T Koerber, Laetitia Comps-Agrar, Steven T Rutherford
Publikováno v: eLife, Vol 8 (2019)
Outer membrane proteins (OMPs) in Gram-negative bacteria dictate permeability of metabolites, antibiotics, and toxins. Elucidating the structure-function relationships governing OMPs within native membrane environments remains challenging. We constru
Externí odkaz: https://doaj.org/article/ce2cff4a5d574858abb6291276ed9aec
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5
Akademický článek
Correction: Corrigendum: A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action
Autor: Ning Chai, Lee R. Swem, Summer Park, Gerald Nakamura, Nancy Chiang, Alberto Estevez, Rina Fong, Lynn Kamen, Elviza Kho, Mike Reichelt, Zhonghua Lin, Henry Chiu, Elizabeth Skippington, Zora Modrusan, Jeremy Stinson, Min Xu, Patrick Lupardus, Claudio Ciferri, Man-Wah Tan
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-2 (2017)
Nature Communications 8: Article number: 14234 (2017); Published: 19 January 2017; Updated: 25 May 2017 This Article contains errors in Fig. 5c. The blue squares should be labelled ‘Water+46B8’ and the green triangles should be labelled ‘Tamifl
Externí odkaz: https://doaj.org/article/fd4f9823a247424798f021121a6f98cd
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6
Modulation of Brain-Derived Neurotrophic Factor (BDNF) Signaling Pathway by Culinary Sage (Salvia officinalis L.)
Autor: Jade Lomax, Shahla Ray, John P. Munafo, Nancy Chiang, Sydney Goertzen, Slavko Komarnytsky, Chi-Tang Ho
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7382, p 7382 (2021)
Culinary sage (Salvia officinalis L.) is a common spice plant in the mint family (Lamiaceae) well known for its distinctive culinary and traditional medicinal uses. Sage tea has been used traditionally as a brain-enhancing tonic and extracts from sag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbe5d69a82e9614f7e6d94a8e42d090
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8
Monoclonal antibody targeting the β-barrel assembly machine of
Autor: Kelly M, Storek, Marcy R, Auerbach, Handuo, Shi, Natalie K, Garcia, Dawei, Sun, Nicholas N, Nickerson, Rajesh, Vij, Zhonghua, Lin, Nancy, Chiang, Kellen, Schneider, Aaron T, Wecksler, Elizabeth, Skippington, Gerald, Nakamura, Dhaya, Seshasayee, James T, Koerber, Jian, Payandeh, Peter A, Smith, Steven T, Rutherford
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 115(14)
The folding and insertion of integral β-barrel membrane proteins into the outer membrane of Gram-negative bacteria is required for viability and bacterial pathogenesis. Unfortunately, the lack of selective and potent modulators to dissect β-barrel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0722df3b236dc0506826ddb05eefe2cf
https://pubmed.ncbi.nlm.nih.gov/29903418
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