Výsledky vyhledávání - "Nancy C. Mcfarland"

Genetic Approaches to the Detection of Contaminants in Escherichia coli Fermentations

Autor: James R. Swartz, Nancy C. Mcfarland

Publikováno v: Biotechnology Progress. 14:88-91

In facilities which cultivate more than one rDNA organism, contamination by the same species is difficult to detect. Since the same species may be producing a different product in an adjacent fermentor or in the same vessel in a subsequent procedure,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080de4ffa0bd78812bcf60ad694fd411
https://doi.org/10.1021/bp970134p

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High-level accumulation of a recombinant antibody fragment in the periplasm of Escherichia coli requires a triple-mutant (degP prc spr) host strain

Autor: Christina Y. Chen, Dana C. Andersen, John C. Joly, John E. Battersby, Kathleen M. Champion, Brad Snedecor, Nancy C. Mcfarland, Julie C. Nishihara

Publikováno v: Biotechnology and bioengineering. 85(5)

During production of a humanized antibody fragment secreted into the periplasm of Escherichia coli, proteolytic degradation of the light chain was observed. In order to determine which protease(s) were responsible for this degradation, we compared ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a89649cea6f4eefb23308668ef46b
https://pubmed.ncbi.nlm.nih.gov/14760686

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