Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Nancy C Andrews"'
Autor:
Courtney E. French, Nancy C. Andrews, Alan H. Beggs, Philip M. Boone, Catherine A. Brownstein, Maya Chopra, Janet Chou, Wendy K. Chung, Alissa M. D’Gama, Ryan N. Doan, Darius Ebrahimi-Fakhari, Richard D. Goldstein, Mira Irons, Christina Jacobsen, Margaret Kenna, Ted Lee, Jill A. Madden, Amar J. Majmundar, Nina Mann, Sarah U. Morton, Annapurna Poduri, Adrienne G. Randolph, Amy E. Roberts, Stephanie Roberts, Matthew G. Sampson, Diane D. Shao, Wanqing Shao, Aditi Sharma, Eliot Shearer, Akiko Shimamura, Scott B. Snapper, Siddharth Srivastava, Jay R. Thiagarajah, Mary C. Whitman, Monica H. Wojcik, Shira Rockowitz, Piotr Sliz
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Boston Children’s Hospital has established a genomic sequencing and analysis research initiative to improve clinical care for pediatric rare disease patients. Through the Children’s Rare Disease Collaborative (CRDC), the hospital offers
Externí odkaz:
https://doaj.org/article/cadfa6ccd3c944fa81c99d9a0a2dceb6
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29495 (2012)
The vestibular apparatus of the vertebrate inner ear uses three fluid-filled semicircular canals to sense angular acceleration of the head. Malformation of these canals disrupts the sense of balance and frequently causes circling behavior in mice. Th
Externí odkaz:
https://doaj.org/article/3563563f4033427c8ef32f89d9245b03
Publikováno v:
PLoS Biology, Vol 2, Iss 3, p E50 (2004)
Divalent metal transporter-1 (DMT1/DCT1/Nramp2) is the major Fe(2+) transporter mediating cellular iron uptake in mammals. Phenotypic analyses of animals with spontaneous mutations in DMT1 indicate that it functions at two distinct sites, transportin
Externí odkaz:
https://doaj.org/article/c627a2814d684997be4fe74b72fa2c4c
Autor:
Roderic I. Pettigrew, Sarah A. Teichmann, Nancy C. Andrews, Arlene S. Bierman, Frederick R. Appelbaum, Cameron J. Turtle, Emer Cooke, John P. A. Ioannidis, Susan E. Bates, Joni L. Rutter, Marcela V. Maus, Hans Clevers, Gerhard Bauer, Marina Cavazzana, Adrian R. Krainer, Harvey V. Fineberg, Michael A. Caligiuri, Donald E. Ingber, Donald B. Kohn, George Q. Daley, Stephen Gottschalk, Jedd D. Wolchok, Victor J. Dzau, David R. Williams, Mohamed Abou-El-Enein, Lawrence S.B. Goldstein, Andre Terzic, Mark Lawler, Lee M. Ellis, Fyodor D. Urnov, Margaret A. Hamburg, Christine L. Mummery, Malcolm K. Brenner, Aris Angelis, Peter W. Marks
Publikováno v:
Abou-el-Enein, M, Angelis, A, Appelbaum, F R, Andrews, N C, Bates, S E, Bierman, A S, Brenner, M K, Cavazzana, M, Caligiuri, M A, Clevers, H, Cooke, E, Daley, G Q, Dzau, V J, Ellis, L M, Fineberg, H V, Goldstein, L S B, Gottschalk, S, Hamburg, M A, Ingber, D E, Kohn, D B, Krainer, A R, Maus, M V, Marks, P, Mummery, C L, Pettigrew, R I, Rutter, J L, Teichmann, S A, Terzic, A, Urnov, F D, Williams, D A, Wolchok, J D, Lawler, M, Turtle, C J, Bauer, G & Ioannidis, J P A 2021, ' Evidence generation and reproducibility in cell and gene therapy research : A call to action ', Molecular Therapy-Methods and Clinical Development, vol. 22, pp. 11-14 . https://doi.org/10.1016/j.omtm.2021.06.012
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 11-14 (2021)
Molecular therapy. Methods & clinical development, 22, 11-14. Nature Publishing Group
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 11-14 (2021)
Molecular therapy. Methods & clinical development, 22, 11-14. Nature Publishing Group
Editorial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338aacefe123d43d370d2aa733485eb8
Autor:
Nancy C. Andrews, Tomas Ganz
Publikováno v:
Molecular Hematology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42f8e5d0057c21156e24648246a3fb08
https://doi.org/10.1002/9781119252863.ch13
https://doi.org/10.1002/9781119252863.ch13
Autor:
Michael Bonadonna, Ferran Celma Nos, Gael Palais, Tomasa Barrientos, Elisabeth Tybl, Sanjay Gupta, Zoubida Karim, Nancy C. Andrews, Mayka Sanchez, Bruno Galy, Hiromi Gunshin
Publikováno v:
HemaSphere
HemaSphere, Lippincott, Williams & Wilkins, 2020, 4 (5), pp.e459. ⟨10.1097/HS9.0000000000000459⟩
HemaSphere, Vol 4, Iss 5, p e459 (2020)
HemaSphere, Lippincott, Williams & Wilkins, 2020, 4 (5), pp.e459. ⟨10.1097/HS9.0000000000000459⟩
HemaSphere, Vol 4, Iss 5, p e459 (2020)
Divalent metal transporter 1 (DMT1) is essential for dietary iron assimilation and erythroid iron acquisition. The 3’ untranslated region of the murine DMT1 mRNA contains an iron responsive element (IRE) that is conserved in humans but whose functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151cd9b7b7ad670f4c63d74902ab502f
http://europepmc.org/articles/PMC7523796
http://europepmc.org/articles/PMC7523796
Autor:
Olivier D. Prince, Jacqueline M. Langdon, Andrew J. Layman, Ian C. Prince, Miguel Sabogal, Howard H. Mak, Alan E. Berger, Chris Cheadle, Francis J. Chrest, Qilu Yu, Nancy C. Andrews, Qian-Li Xue, Curt I. Civin, Jeremy D. Walston, Cindy N. Roy
Publikováno v:
Haematologica, Vol 97, Iss 11 (2012)
Background We and others have shown previously that over-expression of hepcidin antimicrobial peptide, independently of inflammation, induces several features of anemia of inflammation and chronic disease, including hypoferremia, sequestration of iro
Externí odkaz:
https://doaj.org/article/3a08fab1eb3940f9a378f57c43dd5c90
Autor:
Sijin Liu, Rajasekhar N.V.S. Suragani, Anping Han, Wanting Zhao, Nancy C. Andrews, Jane-Jane Chen
Publikováno v:
Haematologica, Vol 93, Iss 5 (2008)
Heme-regulated eIF2α kinase (HRI) is essential for regulating globin translation in iron deficiency and in β-thalassemia. We investigated the role of heme-regulated eIF2α kinase in hemoglobin and red blood cell production as well as in iron homeos
Externí odkaz:
https://doaj.org/article/b2f0a563d865439b8d286e8b21f86837
Autor:
Anant Vatsayan, Fedik Rahimov, Waleed Al-Herz, Colin A. Sieff, Mark D. Fleming, Basel K. al-Ramadi, E. Graham Davies, Michel J. Massaad, Martha Sola-Visner, Raif S. Geha, Narayanaswamy Ramesh, Haifa H. Jabara, Nancy C. Andrews, Wayne Bainter, Eli Silver, David Fraulino, Steven E. Boyden, Rand Arnaout, Salem H. Alshemmari, Sanjay P Ahuja, Louis M. Kunkel, Hasan Al-Dhekri, Mohammad Abu-Shukair, Zhi-Jian Liu, Janet Chou, Toshiro K. Ohsumi, Halli Benson, Luigi D. Notarangelo
Publikováno v:
Nature Genetics. 48:74-78
Patients with a combined immunodeficiency characterized by normal numbers but impaired function of T and B cells had a homozygous p.Tyr20His substitution in transferrin receptor 1 (TfR1), encoded by TFRC. The substitution disrupts the TfR1 internaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554a57ef01a1e625821aeae18c7a69a3
https://doi.org/10.1038/ng.3465
https://doi.org/10.1038/ng.3465
Publikováno v:
Proceedings of the National Academy of Sciences. 112:11714-11719
Transferrin receptor 1 (Tfr1) facilitates cellular iron uptake through receptor-mediated endocytosis of iron-loaded transferrin. It is expressed in the intestinal epithelium but not involved in dietary iron absorption. To investigate its role, we ina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85dae91b20316ac8e5002a9eab65af0
https://doi.org/10.1073/pnas.1511701112
https://doi.org/10.1073/pnas.1511701112