Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nancy B. Wehr"'
Autor:
Michael J Daly, Elena K Gaidamakova, Vera Y Matrosova, Juliann G Kiang, Risaku Fukumoto, Duck-Yeon Lee, Nancy B Wehr, Gabriela A Viteri, Barbara S Berlett, Rodney L Levine
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12570 (2010)
For Deinococcus radiodurans and other bacteria which are extremely resistant to ionizing radiation, ultraviolet radiation, and desiccation, a mechanistic link exists between resistance, manganese accumulation, and protein protection. We show that ult
Externí odkaz:
https://doaj.org/article/1c254163d01c4fb49c698ee02e183923
Autor:
Daniel S. Chertow, Rolf E. Kuestner, Kathie-Anne Walters, Jeffery K. Taubenberger, Rosalind A. Rosenthal, Karl Huffman, Rebecca L. Dunfee, Louis M. Schwartzman, Brett W. Jagger, John C. Kash, Adrian Ozinsky, Rodney L. Levine, Susan R. Doctrow, Judith D. Easterbrook, Nancy B. Wehr, Yongli Xiao, A. Sally Davis, Aline Sandouk
Publikováno v:
Free Radical Biology and Medicine. 67:235-247
The 1918 influenza pandemic caused over 40 million deaths worldwide, with 675,000 deaths in the United States alone. Studies in several experimental animal models showed that 1918 influenza virus infection resulted in severe lung pathology associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d944a50e0632e348df94faa5f2e8c78
https://doi.org/10.1016/j.freeradbiomed.2013.10.014
https://doi.org/10.1016/j.freeradbiomed.2013.10.014
Autor:
Christina Curtis, Gary N Landis, Donna Folk, Nancy B Wehr, Nicholas Hoe, Morris Waskar, Diana Abdueva, Dmitriy Skvortsov, Daniel Ford, Allan Luu, Ananth Badrinath, Rodney L. Levine, Timothy J. Bradley, Simon Tavaré, John Tower
Publikováno v:
Genome Biology
Several interventions increase lifespan in model organisms, including reduced insulin/insulin-like growth factor-like signaling (IIS), FOXO transcription factor activation, dietary restriction, and superoxide dismutase (SOD) over-expression. One ques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ce69407bb45c5b32e45d750ce8d6cf
https://doi.org/10.1186/s13059-016-0959-3
https://doi.org/10.1186/s13059-016-0959-3
Autor:
Nancy B. Wehr, Rodney L. Levine
Publikováno v:
Free Radical Biology and Medicine. 53:1222-1225
Methionine residues in protein can be oxidized by reactive oxygen or nitrogen species to generate methionine sulfoxide. This covalent modification has been implicated in processes ranging from normal cell signaling to neurodegenerative diseases. A ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420c792f543177c9bb206c3e057eba87
https://doi.org/10.1016/j.freeradbiomed.2012.06.036
https://doi.org/10.1016/j.freeradbiomed.2012.06.036
Publikováno v:
Journal of Perinatology. 31:S24-S28
Group B Streptococcus is the most common cause of bacterial infection in the newborn. Our aim was to purify and identify molecules produced by the bacterium, which cause pulmonary hypertension. Guided by bioassays performed in neonatal lambs, we util
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2001039d7f7c7f9bb0522c36d2cadd8
https://doi.org/10.1038/jp.2010.168
https://doi.org/10.1038/jp.2010.168
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1703:135-140
It is well established that many amino acid residues of proteins are susceptible to oxidation by various forms of reactive oxygen species (ROS), and that oxidatively modified proteins accumulate during aging, oxidative stress, and in a number of age-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d374cfa9baa3829bb174c37195a6f73
https://doi.org/10.1016/j.bbapap.2004.08.010
https://doi.org/10.1016/j.bbapap.2004.08.010
Autor:
Rodney L. Levine, Michael W. Eckhaus, Petra Wetzel, Timothy G. Myers, Tae Hoon Lee, Geumsoo Kim, Anthony Wynshaw-Boris, Cornelia Geers, Gerolf Gros, Nancy B. Wehr, Mary Ann Robinson, Jennie W. Owens
Publikováno v:
Molecular and Cellular Biology. 24:9942-9947
Carbonic anhydrase III is a cytosolic protein which is particularly abundant in skeletal muscle, adipocytes, and liver. The specific activity of this isozyme is quite low, suggesting that its physiological function is not that of hydrating carbon dio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902d17ff29a37f8dc104b03983eb7ce5
https://doi.org/10.1128/mcb.24.22.9942-9947.2004
https://doi.org/10.1128/mcb.24.22.9942-9947.2004
Publikováno v:
Proceedings of the National Academy of Sciences. 100:5087-5090
Group B Streptococcus is the most common cause of bacterial infection in the newborn. Infection in many cases causes persistent pulmonary hypertension, which impairs gas exchange in the lung. We purified the bacterial components causing pulmonary hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16dc82c529be4d21aee41169764317e
https://doi.org/10.1073/pnas.0931493100
https://doi.org/10.1073/pnas.0931493100
Autor:
Nancy B. Wehr, Dae-Kyung Kang, Tracey A. Rouault, Rodney L. Levine, Steven K. Drake, Jinsook Jeong
Publikováno v:
Journal of Biological Chemistry. 278:14857-14864
Iron regulatory protein 2 coordinates cellular regulation of iron metabolism by binding to iron responsive elements in mRNA. The protein is synthesized constitutively but is rapidly degraded when iron stores are replete. This iron-dependent degradati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19cf44773d42874fe2d33b5e9c546cf8
https://doi.org/10.1074/jbc.m300616200
https://doi.org/10.1074/jbc.m300616200
Autor:
Raj Hari, Nancy B. Wehr, Vasanti Burde, Ashesh A. Saraiya, Elliot Feldman, Steven Buck, Rodney L. Levine, Aaron Zeevi, John Vettraino, Robert Arking, Kalpana Sathrasala, Sherif Soliman, Kevin Graves
Publikováno v:
Experimental Gerontology. 35:167-185
Patterns of antioxidant gene expression and of oxidative damage were measured throughout the adult life span of a selected long-lived strain (La) of Drosophila melanogaster and compared to that of their normal-lived progenitor strain (Ra). Extended l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654671ef794c12d6eeea3e83cf7a3e49
https://doi.org/10.1016/s0531-5565(99)00094-7
https://doi.org/10.1016/s0531-5565(99)00094-7