Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Nancy Claude"'
Autor:
Joel P. Bercu, Melisa Masuda-Herrera, Alejandra Trejo-Martin, Priyanka Sura, Robert Jolly, Michelle Kenyon, Rob Thomas, David J. Ponting, David Snodin, Gregor Tuschl, Stephanie Simon, Kathleen De Vlieger, Richard Hutchinson, Andreas Czich, Susanne Glowienke, M. Vijayaraj Reddy, Sandra Johanssen, Esther Vock, Nancy Claude, Richard J. Weaver
Publikováno v:
Regulatory Toxicology and Pharmacology. :105415
Autor:
Alexandra Rogue, Carine Lambert, Rozenn Jossé, Sebastien Antherieu, Catherine Spire, Nancy Claude, André Guillouzo
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18816 (2011)
BACKGROUND: Several glitazones (PPARγ agonists) and glitazars (dual PPARα/γ agonists) have been developed to treat hyperglycemia and, simultaneously, hyperglycemia and dyslipidemia, respectively. However, most have caused idiosyncratic hepatic or
Externí odkaz:
https://doaj.org/article/265dc064bc09471885fd9c19bde63a86
Publikováno v:
PPAR Research, Vol 2010 (2010)
Thiazolidinediones are a class of Peroxisome Proliferator Activated Receptor γ (PPARγ) agonists that reduce insulin resistance in type 2 diabetic patients. Although no detectable hepatic toxicity has been evidenced in animal studies during preclini
Externí odkaz:
https://doaj.org/article/e9bb426ae4a94c31ba93dac129512ba8
Genotoxicity of tungsten carbide–cobalt (WC–Co) nanoparticles in vitro: Mechanisms-of-action studies
Publikováno v:
Mutation Research-Reviews
Mutation Research-Reviews, Elsevier, 2015, 779, pp.15-22. ⟨10.1016/j.mrgentox.2015.02.002⟩
Mutation Research-Reviews, 2015, 779, pp.15-22. ⟨10.1016/j.mrgentox.2015.02.002⟩
Mutation Research-Reviews, Elsevier, 2015, 779, pp.15-22. ⟨10.1016/j.mrgentox.2015.02.002⟩
Mutation Research-Reviews, 2015, 779, pp.15-22. ⟨10.1016/j.mrgentox.2015.02.002⟩
We showed previously that tungsten carbide–cobalt (WC–Co) nanoparticles (NP) can be used as a nanoparticulate positive control in some in vitro mammalian genotoxicity assays. Here, we investigate the mechanisms of action involved in WC–Co NP ge
Autor:
Nancy Claude, Brigitte Lindeman, Werner Brueller, Helen Håkansson, Isabelle Leconte, Jyrki Liesivuori, Corrado L. Galli, Leda Kovatsi, Joana P. Miranda, Rolf Schulte-Hermann, Emma Martínez-López, Lesley A. Stanley, Bas J. Blaauboer, Cécile Michel, Aristidis Tsatsakis, Martin F. Wilks, Philippe Bourrinet, Vesna Matović, Marek Murias, Eva Cecilie Bonefeld-Jørgensen, Johanna Zilliacus, Ursula Gundert-Remy, Heather M. Wallace, Dominique Lison, Paul T.J. Scheepers, João Paulo Teixeira, Marie Haag-Grönlund, Nurşen Başaran
Publikováno v:
Toxicology Letters, 259, 151-5
Toxicology Letters, 259, pp. 151-5
Wilks, M F, Blaauboer, B J, Schulte-Hermann, R, Wallace, H M, Galli, C L, Haag-Grönlund, M, Matović, V, Teixeira, J P, Zilliacus, J, Basaran, N, Bonefeld-Jørgensen, E C, Bourrinet, P, Brueller, W, Claude, N, Miranda, J P, Gundert-Remy, U, Håkansson, H, Kovatsi, L, Liesivuori, J, Lindeman, B, Lison, D, Leconte, I, Martínez-López, E, Murias, M, Michel, C, Scheepers, P T J, Stanley, L & Tsatsakis, A 2016, ' The European Registered Toxicologist (ERT) : Current status and prospects for advancement ', Toxicology Letters, vol. 259, pp. 151-5 . https://doi.org/10.1016/j.toxlet.2016.06.014
Toxicology Letters, 259, pp. 151-5
Wilks, M F, Blaauboer, B J, Schulte-Hermann, R, Wallace, H M, Galli, C L, Haag-Grönlund, M, Matović, V, Teixeira, J P, Zilliacus, J, Basaran, N, Bonefeld-Jørgensen, E C, Bourrinet, P, Brueller, W, Claude, N, Miranda, J P, Gundert-Remy, U, Håkansson, H, Kovatsi, L, Liesivuori, J, Lindeman, B, Lison, D, Leconte, I, Martínez-López, E, Murias, M, Michel, C, Scheepers, P T J, Stanley, L & Tsatsakis, A 2016, ' The European Registered Toxicologist (ERT) : Current status and prospects for advancement ', Toxicology Letters, vol. 259, pp. 151-5 . https://doi.org/10.1016/j.toxlet.2016.06.014
Item does not contain fulltext Following its inception in 1994, the certification of European Registered Toxicologists (ERT) by EUROTOX has been recognized as ensuring professional competence as well as scientific integrity and credibility. Criteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628c04a88a36dff4a313042b7e4afdf1
https://hdl.handle.net/10400.18/4070
https://hdl.handle.net/10400.18/4070
Autor:
N. Bécourt-Lhote, Jean Marie Girard, N. Rogez, A. Dekeyne, N. Ribeiro-Palha, Nancy Claude, Véronique Gervais
Publikováno v:
Toxicology Letters. 295:S111
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 689:21-49
During the last decade, there has been clear progress in using threshold in risk assessment but its acceptance by scientists is still under debate. Contrary to indirect DNA-damaging agents, DNA-reactive agents have been assumed to have a non-threshol
Autor:
Nancy Claude
Publikováno v:
Bulletin de l'Académie Nationale de Médecine. 193:1767-1772
RESUME La reduction du recours a l’animal de laboratoire est une des preoccupations essentielles de la communaute scientifique depuis la definition de la regle des « 3 Rs » (Reduction, Raffinement, Remplacement) dans les annees 60. Ce principe, i
Publikováno v:
Toxicology in Vitro. 23:466-475
The use of in vitro human liver cell models is an attractive approach in toxicogenomic studies designed to analyze gene expression changes induced by a toxic chemical. However, in such studies, reliability, reproducibility and interlaboratory concord
Publikováno v:
médecine/sciences. 25:105-110
Pour assurer la securite du patient lors des etudes cliniques ou de la mise sur le marche d’un medicament, la toxicologie a beneficie ces dernieres annees de l’essor des nouvelles connaissances qu’elles soient scientifiques, techniques ou bio-i