Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nancy Aerts"'
Publikováno v:
Psychopharmacology. 232:3911-3920
Paired associates learning (PAL) has been suggested to be predictive of functional outcomes in first episode psychosis and of conversion from mild cognitive impairment to Alzheimer's disease. An automated touch screen-based rodent PAL (rPAL) task has
Publikováno v:
Pharmacology Biochemistry and Behavior. 122:97-106
The use of touch-screen equipped operant boxes is an increasingly popular approach for modeling human cognition in the rodent. However little data is currently available describing the effects of pharmacological manipulations on touch-screen based ta
Autor:
Hassan Rahmoune, Sabine Bahn, Paul C. Guest, Laura W. Harris, Daniel Martins-de-Souza, Nancy Aerts, Ilse Lenaerts, Murtada Alsaif, Bob Amess, Agnes Ernst, Pieter J. Peeters
Publikováno v:
BMC Research Notes, Vol 5, Iss 1, p 146 (2012)
BMC Research Notes
BMC Research Notes
Background: Establishing preclinical models is essential for novel drug discovery in schizophrenia. Most existing models are characterized by abnormalities in behavioral readouts, which are informative, but do not necessarily translate to the symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6dc7ec3cdc29714927d7bddeb8caa7f
https://ora.ox.ac.uk/objects/uuid:d8a5e0f4-4f4b-439e-8c73-c0cc894185e8
https://ora.ox.ac.uk/objects/uuid:d8a5e0f4-4f4b-439e-8c73-c0cc894185e8
Autor:
Nancy Aerts, Anne Simone Josephine Lesage, Ana M.M. Oliveira, Thomas Steckler, Hansfried Van Craenendonck, Anton Megens, Jos Prickaerts, Hilde Lavreysen
Publikováno v:
Psychopharmacology, 179, 198-206. Springer
Group I metabotropic glutamate receptor antagonists, which block both the mGlu1 and mGlu5 receptors, have been shown to have anxiolytic effects in the lick suppression test in rats. The anxiolytic potential of the selective mGlu1 antagonist 3,4-dihyd
Autor:
Anton Megens, Wilhelmus Drinkenburg, Koen A. Hens, Xavier Langlois, Jef Vermeire, Brian Joel Hrupka, John R. Atack, Paul F. Jackson, Kenneth J. Rhodes, Paula te Riele, Annemie L. Y. Wellens, Abdallah Ahnaou, Nancy Aerts, Patrick De Haes, Brian C. Shook, Herman M. R. Hendrickx, Stefanie Rassnick
Publikováno v:
ACS chemical neuroscience. 5(10)
Adenosine A2A antagonists are believed to have therapeutic potential in the treatment of Parkinson’s disease (PD). We have characterized the dual adenosine A2A/A1 receptor antagonist JNJ-40255293 (2-amino-8-[2-(4-morpholinyl)ethoxy]-4-phenyl-5H-ind
Autor:
Javier Fernández, Nancy Aerts, Encarna Matesanz, Thomas Steckler, Andrés A. Trabanco, Shirley Pullan, Rosa M. Alvarez, Inge Boeckx, Antonio Gómez, Frans Eduard Janssens, José Ignacio Andrés, Ana Isabel de Lucas, Leenaerts Joseph Elisabeth
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(14)
Novel 4-phenyl-4-[1H-imidazol-2-yl]-piperidine derivatives have been prepared and their synthesis described herein. In vitro affinities for delta-, micro-, and kappa-opioid receptors are reported. Evaluation of some representative compounds from this
Autor:
Ziv Shkedy, Veerle Vandersmissen, Geert Molenberghs, Hansfried Van Craenendonck, Nancy Aerts, Thomas Steckler, Luc Bijnens
Publikováno v:
Biometrical Journal; Jun2005, Vol. 47 Issue 3, p286-298, 13p