Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Nancy, Wertz"'
Publikováno v:
Annual review of animal biosciences. 5
We describe the domestication of the species, explore its value to agriculture and bioscience, and compare its immunoglobulin (Ig) genes to those of other vertebrates. For encyclopedic information, we cite earlier reviews and chapters. We provide cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643ef4edc6d05caf7d59d2b3ce4466b0
https://pubmed.ncbi.nlm.nih.gov/28199170
https://pubmed.ncbi.nlm.nih.gov/28199170
Publikováno v:
Molecular Immunology. 55:319-328
We characterized 239 lambda rearrangements from fetal and germfree (GF) piglets to: (1) determine if transcripts recovered from the earliest sites of B cell lymphogenesis were unique (2) determine what proportion of the genome is used to form the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a618c8893abfd9cba31c24bf388312
https://doi.org/10.1016/j.molimm.2013.03.012
https://doi.org/10.1016/j.molimm.2013.03.012
Publikováno v:
Immunology. 138:134-144
Infection of germ-free isolator piglets with swine influenza (S-FLU) that generates dsRNA during replication causes elevation of immunoglobulins in serum and bronchoalveolar lavage, a very weak response to trinitrophenyl conjugates but an immune resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128f8cc900e2fbc3a1a3619c7d9859dd
https://doi.org/10.1111/imm.12018
https://doi.org/10.1111/imm.12018
Autor:
David L. Francis, Marek Sinkora, Kristina Santiago-Mateo, Xiu-Zhu Sun, Nancy Wertz, John E. Butler
Publikováno v:
Developmental and comparative immunology. 65
The ileal Peyers patches (IPP) of newborn germfree (GF) piglets were isolated into blind loops and the piglets colonized with a defined probiotic microflora. After 5 weeks, IgA levels in the intestinal lavage (IL) of loop piglets remained at GF level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2bcf4ed8d20cdada8496ca5a0ee24d
https://pubmed.ncbi.nlm.nih.gov/27497872
https://pubmed.ncbi.nlm.nih.gov/27497872
Publikováno v:
Molecular Immunology. 52:97-107
The number of immunoglobulin heavy chain (IGH) constant genes (IGHC) varies among mammals. To annotate the porcine IGHC genes, we sequenced the entire IGHC-containing genomic region from a single porcine haplotype. The resulting contiguous sequence i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ccee2b9f9fa85ce607f5cf4593ac3e
https://doi.org/10.1016/j.molimm.2012.05.010
https://doi.org/10.1016/j.molimm.2012.05.010
Autor:
John E. Butler, Katerina Stepanova, Marek Sinkora, Kelly M. Lager, Nancy Wertz, Xiu-Zhu Sun, Gregory J. Tobin
Publikováno v:
Immunology. 137:149-159
VDJ and VJ rearrangements, expression of RAG-1, Tdt and VpreB, and the presence of signal joint circles (SJC) were used to identify sites of B-cell lymphogenesis. VDJ, VλJλ but not VκJκ rearrangements or SJC were recovered from yolk sac (YS) at 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa165275d3e7f0aa82fb40ca3e4437af
https://doi.org/10.1111/j.1365-2567.2012.03615.x
https://doi.org/10.1111/j.1365-2567.2012.03615.x
Publikováno v:
Immunogenetics. 64:469-473
Six putative subclasses of expressed porcine IgG have been described from gene sequences and allotypic variants for five of these have been proposed. We tested this hypothesis by studying the transcription of these 11 variants in outbred hemizygous f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc3847675da4ea90233080f5471a1fc
https://doi.org/10.1007/s00251-012-0603-7
https://doi.org/10.1007/s00251-012-0603-7
Autor:
Peter L. Nara, Xuizhu Sun, Joseph F. Urban, Kathryn Chaloner, John E. Butler, Kelly M. Lager, Nancy Wertz, Gregory J. Tobin, David L. Francis
Publikováno v:
Molecular Immunology. 49:483-494
Usage of variable region gene segments during development of the antibody repertoire in mammals is unresolved in part because of the complexity of the locus in mice and humans and the difficulty of distinguishing intrinsic from extrinsic influences i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94f8bea8255b05f933ea34438a9c54e0
https://doi.org/10.1016/j.molimm.2011.09.018
https://doi.org/10.1016/j.molimm.2011.09.018
Publikováno v:
Developmental & Comparative Immunology. 35:421-430
Myotis lucifugus populations in Northeastern US are being decimated by a fungal disease. Since almost nothing is known about the immune system of bats, we are characterizing the immunoglobulin genes of bats. We show that M. lucifugus has a diverse V(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bdb3e4f5bdfa263a80631a7cc1681e
https://doi.org/10.1016/j.dci.2010.06.004
https://doi.org/10.1016/j.dci.2010.06.004
Autor:
A. Vance, Todd Vaught, Jeff A. Monahan, Irina A. Polejaeva, Peter M. Jobst, Y. Dai, Jeremy Boone, M. Mendicino, Carol Phelps, Kevin D. Wells, David Ayares, LeRoith T, J. Ramsoondar, Xiu-Zhu Sun, Dandro A, Suyapa Ball, John E. Butler, Nancy Wertz, Bergman Z, S. Chen
Publikováno v:
Transgenic Research
A poly(A)-trap gene targeting strategy was used to disrupt the single functional heavy chain (HC) joining region (J(H)) of swine in primary fibroblasts. Genetically modified piglets were then generated via somatic cell nuclear transfer (SCNT) and bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c4ea951a94f7738e116c018371340d
https://doi.org/10.1007/s11248-010-9444-z
https://doi.org/10.1007/s11248-010-9444-z