Zobrazeno 1 - 10 of 75 pro vyhledávání: '"Nancy, Standart"'
1
Akademický článek
Dual RNA Processing Roles of Pat1b via Cytoplasmic Lsm1-7 and Nuclear Lsm2-8 Complexes
Autor: Caroline Vindry, Aline Marnef, Helen Broomhead, Laure Twyffels, Sevim Ozgur, Georg Stoecklin, Miriam Llorian, Christopher W. Smith, Juan Mata, Dominique Weil, Nancy Standart
Publikováno v: Cell Reports, Vol 20, Iss 5, Pp 1187-1200 (2017)
Summary: Pat1 RNA-binding proteins, enriched in processing bodies (P bodies), are key players in cytoplasmic 5′ to 3′ mRNA decay, activating decapping of mRNA in complex with the Lsm1-7 heptamer. Using co-immunoprecipitation and immunofluorescenc
Externí odkaz: https://doaj.org/article/2f6fe9b5367b4152b16ee47c95180113
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2
Akademický článek
GC content shapes mRNA storage and decay in human cells
Autor: Maïté Courel, Yves Clément, Clémentine Bossevain, Dominika Foretek, Olivia Vidal Cruchez, Zhou Yi, Marianne Bénard, Marie-Noëlle Benassy, Michel Kress, Caroline Vindry, Michèle Ernoult-Lange, Christophe Antoniewski, Antonin Morillon, Patrick Brest, Arnaud Hubstenberger, Hugues Roest Crollius, Nancy Standart, Dominique Weil
Publikováno v: eLife, Vol 8 (2019)
mRNA translation and decay appear often intimately linked although the rules of this interplay are poorly understood. In this study, we combined our recent P-body transcriptome with transcriptomes obtained following silencing of broadly acting mRNA d
Externí odkaz: https://doaj.org/article/984956c05d1a4d48923e9135c8f90307
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3
Akademický článek
Structure of a Human 4E-T/DDX6/CNOT1 Complex Reveals the Different Interplay of DDX6-Binding Proteins with the CCR4-NOT Complex
Autor: Sevim Ozgur, Jérôme Basquin, Anastasiia Kamenska, Witold Filipowicz, Nancy Standart, Elena Conti
Publikováno v: Cell Reports, Vol 13, Iss 4, Pp 703-711 (2015)
The DEAD-box protein DDX6 is a central component of translational repression mechanisms in maternal mRNA storage in oocytes and microRNA-mediated silencing in somatic cells. DDX6 interacts with the CCR4-NOT complex and functions in concert with sever
Externí odkaz: https://doaj.org/article/903d595b890a412ea3653c5abc93bf5d
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4
Akademický článek
CPEB and miR-15/16 Co-Regulate Translation of Cyclin E1 mRNA during Xenopus Oocyte Maturation.
Autor: Ania Wilczynska, Anna Git, Joanna Argasinska, Eulàlia Belloc, Nancy Standart
Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0146792 (2016)
Cell cycle transitions spanning meiotic maturation of the Xenopus oocyte and early embryogenesis are tightly regulated at the level of stored inactive maternal mRNA. We investigated here the translational control of cyclin E1, required for metaphase
Externí odkaz: https://doaj.org/article/6678fd25bde74d9f9216efdc54c66d5d
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7
Akademický článek
Investigating the consequences of eIF4E2 (4EHP) interaction with 4E-transporter on its cellular distribution in HeLa cells.
Autor: Dorota Kubacka, Anastasiia Kamenska, Helen Broomhead, Nicola Minshall, Edward Darzynkiewicz, Nancy Standart
Publikováno v: PLoS ONE, Vol 8, Iss 8, p e72761 (2013)
In addition to the canonical eIF4E cap-binding protein, eukaryotes have evolved sequence-related variants with distinct features, some of which have been shown to negatively regulate translation of particular mRNAs, but which remain poorly characteri
Externí odkaz: https://doaj.org/article/124348df34a54d1da0266382bd79e231
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8
Mutations in genes encoding regulators of mRNA decapping and translation initiation: links to intellectual disability
Autor: Nancy Standart, Dominique Weil, Davor Lessel, Amélie Piton
Publikováno v: Biochemical Society Transactions
Biochemical Society Transactions, 2020, 48 (3), pp.1199-1211. ⟨10.1042/BST20200109⟩
Biochemical Society Transactions, Portland Press, 2020, 48 (3), pp.1199-1211. ⟨10.1042/BST20200109⟩
International audience; Intellectual disability (ID) affects at least 1% of the population, and typically presents in the first few years of life. ID is characterized by impairments in cognition and adaptive behavior and is often accompanied by furth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6a9b5595df6a22ab487f97df1159fc
https://hal.sorbonne-universite.fr/hal-02934276
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9
GC content shapes mRNA storage and decay in human cells
Autor: Caroline Vindry, Michèle Ernoult-Lange, Hugues Roest Crollius, Michel Kress, Dominique Weil, Zhou Yi, Clémentine Bossevain, Antonin Morillon, Marie-Noëlle Benassy, Yves Clément, Nancy Standart, Maïté Courel, Marianne Bénard, Arnaud Hubstenberger, Patrick Brest, Christophe Antoniewski, Olivia Vidal Cruchez, Dominika Foretek
Publikováno v: eLife
eLife, eLife Sciences Publication, 2019
eLife, Vol 8 (2019)
eLife, eLife Sciences Publication, 2019, 8, pp.e49708. ⟨10.7554/elife.49708⟩
eLife, eLife Sciences Publication, 2019, 8, ⟨10.7554/eLife.49708⟩
eLife, 2019, 8, pp.e49708. ⟨10.7554/elife.49708⟩
International audience; mRNA translation and decay appear often intimately linked although the rules of this interplay are poorly understood. In this study, we combined our recent P-body transcriptome with transcriptomes obtained following silencing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273caaeb21d90d33938bbbfaebe17979
https://hal.archives-ouvertes.fr/hal-03023372
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