Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nancie Archin"'
Autor:
Lijun Ling, Manse Kim, Andrew Soper, Martina Kovarova, Rae Ann Spagnuolo, Nurjahan Begum, Jennifer Kirchherr, Nancie Archin, Diana Battaglia, Dave Cleveland, Angela Wahl, David M. Margolis, Edward P. Browne, J. Victor Garcia
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT The HIV reservoir is more dynamic than previously thought with around 70% of the latent reservoir originating from viruses circulating within 1 year of the initiation of antiretroviral therapy (ART). In an ex vivo model system of HIV latency
Externí odkaz:
https://doaj.org/article/11242e5bc7854ce8b4f92e9d3644d4a7
Autor:
Lesia Semenova, Yingfan Wang, Shane Falcinelli, Nancie Archin, Alicia D Cooper-Volkheimer, David M Margolis, Nilu Goonetilleke, David M Murdoch, Cynthia D Rudin, Edward P Browne
Publikováno v:
eLife, Vol 13 (2024)
Understanding the interplay between the HIV reservoir and the host immune system may yield insights into HIV persistence during antiretroviral therapy (ART) and inform strategies for a cure. Here, we applied machine learning (ML) approaches to cross-
Externí odkaz:
https://doaj.org/article/920a8415331d4a749444f904e83bf7e9
Autor:
Yinyan Xu, Ann Marie Weideman, Maria Abad-Fernandez, Katie R. Mollan, Sallay Kallon, Shahryar Samir, Joanna A. Warren, Genevieve Clutton, Nadia R. Roan, Adaora A. Adimora, Nancie Archin, JoAnn Kuruc, Cynthia Gay, Michael G. Hudgens, Nilu Goonetilleke
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/e9b7bccce8f04b7282b4fa07b74dfa63
Autor:
Yinyan Xu, Ann Weideman, Maria Abad-Fernandez, Katie Mollan, Sallay Kallon, Shahryar Samir, Joanna Warren, Genevieve Clutton, Nadia Roan, Adaora Adimora, Nancie Archin, JoAnn Kuruc, Cindy Gay, Michael Hudgens, Nilu Goonetilleke
Publikováno v:
Bio-Protocol, Vol 12, Iss 6 (2022)
The human immunodeficiency virus (HIV)-1 viral inhibition assay (VIA) measures CD8+ T cell-mediated inhibition of HIV replication in CD4+ T cells and is increasingly used for clinical testing of HIV vaccines and immunotherapies. Different VIAs that d
Externí odkaz:
https://doaj.org/article/4fcbd10f8f5a4634b53247bab58fbb0e
Autor:
Yinyan Xu, Ann Marie Weideman, Maria Abad-Fernandez, Katie R. Mollan, Sallay Kallon, Shahryar Samir, Joanna A. Warren, Genevieve Clutton, Nadia R. Roan, Adaora A. Adimora, Nancie Archin, JoAnn Kuruc, Cynthia Gay, Michael G. Hudgens, Nilu Goonetilleke
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The HIV-1 viral inhibition assay (VIA) measures CD8 T cell-mediated inhibition of HIV replication in CD4 T cells and is increasingly used for clinical testing of HIV vaccines and immunotherapies. The VIA has multiple sources of variability arising fr
Externí odkaz:
https://doaj.org/article/32e8175645234885b292b56eb63175ad
Autor:
Joanna A Warren, Shuntai Zhou, Yinyan Xu, Matthew J Moeser, Daniel R MacMillan, Olivia Council, Jennifer Kirchherr, Julia M Sung, Nadia R Roan, Adaora A Adimora, Sarah Joseph, JoAnn D Kuruc, Cynthia L Gay, David M Margolis, Nancie Archin, Zabrina L Brumme, Ronald Swanstrom, Nilu Goonetilleke
Publikováno v:
eLife, Vol 9 (2020)
HIV-1-specific CD8+ T cells are an important component of HIV-1 curative strategies. Viral variants in the HIV-1 reservoir may limit the capacity of T cells to detect and clear virus-infected cells. We investigated the patterns of T cell escape varia
Externí odkaz:
https://doaj.org/article/a3918d4bf49a4fd09760d0e0944dc9eb
Autor:
Julia M. Sung, JoAnnD Kuruc, Matthew Clohosey, Amanda Crooks, Shabnum Patel, Lauren Roesch, Patrick Hanley, CRussell Cruz, Nancie Archin, JosephJ Eron, Nilu Goonetilleke, Cliona M. Rooney, Catherine M. Bollard, David M. Margolis, Cynthia L. Gay
Publikováno v:
Journal of Virus Eradication, Vol 3, Iss , Pp 15- (2017)
Externí odkaz:
https://doaj.org/article/be8b7e2ce506452db31baefed756b7f7
Autor:
Steven G, Deeks, Nancie, Archin, Paula, Cannon, Simon, Collins, R Brad, Jones, Marein A W P, de Jong, Olivier, Lambotte, Rosanne, Lamplough, Thumbi, Ndung'u, Jeremy, Sugarman, Caroline T, Tiemessen, Linos, Vandekerckhove, Sharon R, Lewin, Edward Nelson, Kankaka
Publikováno v:
Nature medicine. 27(12)
Despite the success of antiretroviral therapy (ART) for people living with HIV, lifelong treatment is required and there is no cure. HIV can integrate in the host genome and persist for the life span of the infected cell. These latently infected cell
Autor:
Joanna A Warren, Shuntai Zhou, Yinyan Xu, Matthew J Moeser, Daniel R MacMillan, Olivia Council, Jennifer Kirchherr, Julia M Sung, Nadia R Roan, Adaora A Adimora, Sarah Joseph, JoAnn D Kuruc, Cynthia L Gay, David M Margolis, Nancie Archin, Zabrina L Brumme, Ronald Swanstrom, Nilu Goonetilleke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::064b045a0938f1920bb2b5dee62c7db6
https://doi.org/10.7554/elife.57246.sa2
https://doi.org/10.7554/elife.57246.sa2
Autor:
Julia A. Sung, Shabnum Patel, Matthew L. Clohosey, Lauren Roesch, Tamara Tripic, JoAnn D. Kuruc, Nancie Archin, Patrick J. Hanley, C. Russell Cruz, Nilu Goonetilleke, Joseph J. Eron, Clio M. Rooney, Cynthia L. Gay, Catherine M. Bollard, David M. Margolis
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 26(10)
Adoptive T cell therapy has had dramatic successes in the treatment of virus-related malignancies and infections following hematopoietic stem cell transplantation. We adapted this method to produce ex vivo expanded HIV-specific T cells (HXTCs), with