Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Nanami Gotoh"'
Autor:
Noriyuki Takahashi, Takayuki Saitoh, Nanami Gotoh, Yasuhiro Nitta, Lobna Alkebsi, Tetsuhiro Kasamatsu, Yusuke Minato, Akihiko Yokohama, Norifumi Tsukamoto, Hiroshi Handa, Hirokazu Murakami
Publikováno v:
BMC Immunology, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background T-helper cell type 1 (Th1) polarization in chronic immune thrombocytopenia (cITP) has been reported at the protein and mRNA levels. We evaluated the impact of Th1/Th2 cytokine and cytokine receptor functional polymorphisms on both
Externí odkaz:
https://doaj.org/article/564407817b7e4265a9a5e4e2eec76701
Autor:
Maaya Awata-Shiraiwa, Akihiko Yokohama, Yukihiro Kanai, Nanami Gotoh, Tetsuhiro Kasamatsu, Hiroshi Handa, Takayuki Saitoh, Hirokazu Murakami, Junko Hirato, Hayato Ikota, Norifumi Tsukamoto
Publikováno v:
Acta Haematologica.
Introduction Waldenström macroglobulinemia (WM) represents a subset of lymphoplasmacytic lymphoma (LPL) with the immunoglobulin (Ig)M paraprotein. MYD88 L265P and CXCR4 mutations are common mutations in WM patients, and mutations in ARID1A and KMT2D
Publikováno v:
Cell Proliferation.
Autor:
Tetsuhiro Kasamatsu, Maaya Awata-Shiraiwa, Rei Ishihara, Yuki Murakami, Yuta Masuda, Nanami Gotoh, Tsukasa Oda, Akihiko Yokohama, Ikuko Matsumura, Hiroshi Handa, Norifumi Tsukamoto, Hirokazu Murakami, Takayuki Saitoh
Cellular senescence refers to a pause in the cell cycle, usually in response to internal and/or external stress, including telomere dysfunction, abnormal cellular growth, and DNA damage. Several chemotherapeutic drugs, such as melphalan (MEL) and dox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b22ab39c17f040e6f75602f9bd14e57
https://doi.org/10.21203/rs.3.rs-2058604/v1
https://doi.org/10.21203/rs.3.rs-2058604/v1
Autor:
Nanami Gotoh, Keiko Okuda, Hiroshi Handa, Takayuki Saitoh, Takayuki Yamashita, Ruri Nakamura, Hirokazu Murakami, Tsukasa Oda, Tetsuhiro Kasamatsu
Publikováno v:
Cancer Gene Therapy. 29:225-240
Major histocompatibility complex class II (MHC II) is important for the adaptive immune response because MHC II presents processed antigens to a cluster of differentiation 4 (CD4)-positive T-cells. Conventional doses of chemotherapeutic agents induce
Autor:
Hirokazu Murakami, Takayuki Saitoh, Yuuju Kanayama, Nanami Gotoh, Rei Ishihara, Yuki Murakami, Maaya Awata, Yuta Masuda, Hiroshi Handa, Tetsuhiro Kasamatsu
Publikováno v:
The Kitakanto Medical Journal. 70:315-323
Autor:
Rei Ishihara, Tsukasa Oda, Yuki Murakami, Ikuko Matsumura, Saki Watanabe, Yuta Asao, Yuta Masuda, Nanami Gotoh, Tetsuhiro Kasamatsu, Hisashi Takei, Nobuhiko Kobayashi, Nobuo Sasaki, Takayuki Saitoh, Hirokazu Murakami, Hiroshi Handa
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2216
Volume 24
Issue 3
Pages: 2216
Tissue inhibitors of metalloproteinases (TIMPs) are endogenous matrix metalloproteinase inhibitors. TIMP1 is produced by cancer cells and has pleiotropic activities. However, its role and source in multiple myeloma (MM) are unclear. Here, we evaluate
Autor:
Yuta Masuda, Rei Ishihara, Yuki Murakami, Saki Watanabe, Yuta Asao, Nanami Gotoh, Tetsuhiro Kasamatsu, Hisashi Takei, Nobuhiko Kobayashi, Takayuki Saitoh, Hirokazu Murakami, Hiroshi Handa
Publikováno v:
International journal of hematology.
Human endogenous retroviruses (HERVs) are retrotransposons that infect human germline cells and occupy 5-8% of the human genome. Their expression, though inhibited by mutation, deletion, and epigenetic mechanisms under normal conditions, is associate
Autor:
Yuki Murakami, Kei Kimura-Masuda, Tsukasa Oda, Ikuko Matsumura, Yuta Masuda, Rei Ishihara, Saki Watanabe, Yuko Kuroda, Tetsuhiro Kasamatsu, Nanami Gotoh, Hisashi Takei, Nobuhiko Kobayashi, Takayuki Saitoh, Hirokazu Murakami, Hiroshi Handa
Publikováno v:
Genes; Volume 14; Issue 1; Pages: 100
MicroRNAs (miRNAs and miRs) are small (19–25 base pairs) non-coding RNAs with the ability to modulate gene expression. Previously, we showed that the miR-34 family is downregulated in multiple myeloma (MM) as the cancer progressed. In this study, w
Autor:
Tetsuhiro, Kasamatsu, Nao, Hashimoto, Nao, Sakaya, Maaya, Awata-Shiraiwa, Rei, Ishihara, Yuki, Murakami, Yuta, Masuda, Nanami, Gotoh, Kazue, Nagai, Tsukasa, Oda, Akihiko, Yokohama, Takayuki, Saitoh, Hiroshi, Handa, Norifumi, Tsukamoto, Kunihiko, Hayashi, Hirokazu, Murakami
Publikováno v:
Clinical and experimental medicine. 21(2)
Single-nucleotide polymorphisms (SNPs) of the IDO1 and IDO2 genes have been associated with some diseases. Here, we investigated the association of IDO1 and IDO2 SNPs with the susceptibility to multiple myeloma (MM) and their relationships with MM cl